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ConclusionF022 from Radix Isatidis can not only destroy the structure of endotoxin, but also obstruct the signal transduction pathways of LPS. F022 may be a strong antiendotoxin fraction in drugs research and development.

结论F022部位不仅直接破坏内毒素结构,且阻断内毒素引起的信号传导通路,从而抑制机体炎性因子的过度释放、抑制膜结构伸展刺突蛋白和丝裂原活化蛋白激酶的表达,从分子水平阐明了板蓝根中活性部位F022抗内毒素的分子机理。

Overall, these factors affected the crispness of pickled cowpea directly or indirectly.

总体来说,各因子可能均对豇豆脆度有直接或间接的影响。

In conclusion, HCV-specific CD8+ cells inhibit viral RNA replication by cytokine-mediated and direct cytolytic effects.

总之,HCV特异性CD8+细胞通过细胞因子介导和直接溶细胞效应抑制了病毒RNA的复制。

But its limitation of invasive technique and high cost made the noninvasive and low cost brachioankle pulse wave velocity became a new possible predictor of ventricular arrhythmias on patient under hemodialysis. But no study had been done for the correlation of baPWV and ventricular arrhythmias directively on the patients under hemodialysis.

但是因其为侵入性技术且成本偏高的限制,使得非侵袭性且低成本的上臂足踝脉波速率,成为接受血液透析患者发生心律不整的一个可能预测因子,但是未曾直接探讨过彼此之间的关联。

Recent studies onfish revealed the neuroendocrine interactions between the gonadotropic axis and the somatotropic axis.

在生长激素对性腺的作用方面,发现生长激素能促进鱼类性腺发育和成熟;在鱼类性腺有直接结合生长激素以及传递生长激素作用的胰岛素样生长因子的作用位点,对性腺产生作用。

Methods Granulocyte/macrophage colony stimulating factors and interleukin 4 were used to cultivate DC from peripheral blood of hepatocellular carcinoma patients.Tumor associated antigen extracted from human liver cancer HepG2 cell line was used to activate the DC,which will initiate homogenic T lymphocyte to form cytotoxic T lymphocyte.HepG2 cells were transplanted to the nude mice and were treated with CTL.Expression of PCNA in tumor cells was evaluated.

联合应用粒/巨细胞集落刺激因子及白介素-4(IL-4)直接从肝癌患者外周血中培养出DC;以源于人肝癌细胞系HepG2细胞的肿瘤抗原粗提物刺激DC;DC激活同源的T淋巴细胞产生细胞毒性T淋巴细胞;建立人肝癌细胞系HepG2裸鼠移植瘤模型;CTL治疗人肝癌细胞系HepG2裸鼠移植瘤;检测移植瘤标本肿瘤细胞PCNA表达水平。

TSPG has the similar effect as HGFs, can directly or/and indirected effect and regulate proliferation and differentiation of CD34〓 HSC/HPC to bring into full play in"invigorating qi"of Panax ginseng. 2. During the process of the extensive proliferation, orderly differentiation, functional activation and gene transfer of hematopoietic stem/progenitor cells in ex vivo culture systems, TSPG may be used to regulate the proliferation and differentiation of hematopoietic cells to perform potential application in the domain of hematpoietic stem cell engineering.

我们的研究结果提示:1、TSPG具有类似造血生长因子的功效,能直接或间接影响和调控造血干/祖细胞的增殖与分化,促进血细胞的生成,从而发挥人参&补气生血&之功效。2、在进行对造血干/祖细胞的扩增与诱导分化,功能激活,基因转染等造血干细胞工程研究中可利用人参皂甙的药理作用来调控细胞的增殖分化,发挥其在造血干细胞工程领域的潜在应用价值。

Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats. Pain 2000;86:185-194.[16]Knox RJ, Isaac L. Effects of selective and non-selective kappa-opioid receptor agonists on cutaneous C-fiber-evoked responses of rat dorsal horn neurons.

在慢性炎症及神经损伤或过敏等引起的伤害性感受中,大量的Dyn A生成,通过NMDA 受体直接或间接地产生一些炎性介质或细胞因子,从而加强神经病理性疼痛的形成,其作用机制有待于我们进一步去探讨。

The directly computed theoretical harmonic force field was scaled with a set of scaling factors transferred from related molecules to obtain a prediction of fundamental frequencies. The mean deviation between prediction and experimental IR spectrum of γ-picolinic acid in solid phase was 20cm^-^1(23cm^-^1 for in-plane modes, 11cm^-^1 for out-of-plane ones).

直接理论计算的谐性力场经由相关分子转移来的校正因子校正后,得到的振动基频的预测值和固体样品红外光谱实验值之间的平均偏差为20cm^-^1(面内振动23cm^-^1,面外振动11cm^-^1)。

The mechanism may be it can interference the thermotaxic center, descend the level of plasma cellular factor TNF - one of the endogenous pyrogens, inhibit the synthesis and release of central febril media PGE〓 and cAMP.

其机理可能与直接干扰体温调节中枢作用,降低血浆中作为内生致热原之一的细胞因子TNF水平,抑制中枢发热介质PGE〓、cAMP的合成释放等有关。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。