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盐酸普鲁卡因

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Aim To study the influence of light and heat on the stability of procaine hydrochloride injection.

目的研究盐酸普鲁卡因注射液在光和热同时作用下的稳定性。

Objective: to establish a fast identification method of procaine hydrochloride injection according to the need of marketplace.

目的:为适应市场需求,建立盐酸普鲁卡因注射液的快速鉴别方法。

What are the principles of the identification of Procaine Hydrochloride.

盐酸普鲁卡因的鉴别原理是什么?

Characteristics of the fluorescence reaction between procaine and BSA protein were investigated.

目的研究了盐酸普鲁卡因在血清蛋白环境中的荧光特征,建立了一种灵敏的盐酸普鲁卡因荧光分析技术。

Methods: identification of procaine hydrochloride injection was carried out by chemical reaction and tlc.

采用化学反应和薄层色谱法对盐酸普鲁卡因注射液进行检测。

To compare the methods for the determination of the stability and validity duration of procaine hydrochloride injection.

比较考察盐酸普鲁卡因注射液稳定性及有效期不同方法的优越性。

OBJECTIVE To prepare compound injection of procaine hydrochloride in order to overcome the short comings of single injection of procaine hydrochloride.

目的:研制一种复方盐酸普鲁卡因注射液以解决单方普鲁卡因注射液存在的缺点和不足。

Aminobenzoic acid in procaine hydrochlorid compound injections was determined by differential spectrophotometry and Glenn's method of orthogonal function.

复方盐酸普鲁卜因注射液是盐酸普鲁卡因和对氨基苯甲酸为主要成份的注射剂,一用重氮化法必须分离后进行测定〔'〕。

Methods: By using microelectrode technique the action potentials on guinea pig papillary muscle AP(subscript PM and AP on sinuatrial node AP(subscript SN were induced and the effects of Zaoboniug granula on AP and AP were observed.

豚鼠20只分为早搏宁冲剂组(n=10)与盐酸普鲁卡因胺组(n=10), 2组均采用累积浓度给药法给药,常规微电极技术引导豚鼠心室乳头肌快反应动作电位AP(下标 PM。另取豚鼠16只分为早搏宁冲剂组(n=10)与盐酸普鲁卡因胺组(n=6),同法给药、引导窦房结优势起搏细胞动作电位AP

Results: Zaoboning granula at different doses could inhibit the action potential amplitude and maximal upstroke velocity, prolong the action potential duration, ERP /APD90 of AP, and suppress the diastole depolarization rate, prolong the sinuatrial circle length of AP.

示波器照像记录实验结果。观察早搏宁冲剂低、中、高浓度0.1gL^(-1, 0.2gL^(-1), 0.3gL^(-1)对AP及AP各指标的影响,并与盐酸普鲁卡因胺比较。结果:早搏宁冲剂可降低豚鼠AP的动作电位幅值及0期最大除极速率v(下标 max,延长动作电位时程,同时降低AP的4期除极速率,延长窦性周长。

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