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Addison's disease, also known as hypoadrenocorticism, is a reduction of production of glucocorticoids and mineralocorticoids by the adrenal glands.

阿狄森氏病,又名肾上腺皮质功能减退,是肾上腺分泌的糖皮质激素和盐皮质激素减少。

The effects of zinc deficiency on the serum cortisol and adrenocorticotrophic hormone concentration,and the cerebrum nitric oxide synthase activity in rats were studied.

就缺锌对大鼠血液皮质醇和促肾上腺皮质激素含量以及大脑皮质NO合酶活性的影响进行了研究。

To evaluate the effect of cold stress on hypothalamic-pituitary-adrenal HPA axis in chic-kens,15-day-old male Isa chickens were subjected to acute(for 15min,1h,3h,6h,12h and 24h,respectively) and chronic(for 5d,10d and 20d,respectively) cold stress at 12℃±1℃.The level of expression of corticotropin releasing hormone mRNA in hypothalami and the contents of adrenocorticotrophic hormone,aldosterone and cortisol in serum of the chickens were detected.

为探明冷应激对雏鸡下丘脑-垂体-肾上腺皮质轴的影响,对15日龄公雏鸡进行了急性(15min、1h、3h、6h、12h和24h)与慢性(5d、10d和20d)冷应激处理(12℃±1℃),检测了雏鸡下丘脑促肾上腺皮质激素释放激素mRNA的表达水平及血清促肾上腺皮质激素、醛固酮及皮质醇的含量。

METHODS: Measurement of palatal raphe area first three-dimensional reconstruction of images at up to nasion plane centerline, whichever was determined as a reference surface plane, selection one point on incisor cervix in this line, to measurement of the available palatal bone height; sagittal views were selected at 6 mm dorsally from the incisive canal. The available bone height was defined as the distance from the palatal baseline (lower cortical border of the palate) to the nasal cavity (upper cortical border of the nasal cavity).

先在三维重建图像上以鼻根为准确定面中线平面为参考平面,在此线上选择1个位于中切牙牙颈部的点,在其矢状位图像上,选取位于口腔内侧骨皮质上距切牙孔后缘6 mm处为标测点,通过此点向硬腭做垂线确定腭骨厚度,测量范围自口腔内腭部骨皮质外侧边缘至鼻腔侧骨皮质外侧边缘。

Abstract] objective to improve the diagnosis of non-ossifying fiboma by analysing its x-ray feature.methods plain x-ray films was performed in all patients.x-ray finding in 8 cases with pathologically-confirmed non-ossifying were analyzed.results the clinical symptom was mild,the lesions occurred usually at the metaphysis of the long bones,the affected bones included femur(n=4),tibia(n=3),humerus(n=1).cortical type was seen in 5 cases,presenting as unilocular or multilacular transparent areas with in the cortex or tightly beneath the cortex,the lesion had a sclerotic margin.which was more obvious at the marrow side.medullary type was seen in 2 cases.the lesion was located at the center of the bone and grew centrally.the tumor was manifested as unilocular or multilocular.tramsparent area with sclerotic border and the bone cortex became thinner with slightly expanding on 11 sides.conclusion plain radiography is the elementally means to detect this disease.based on the typical x-ray signs of non-ossifying fibroma combined with clinical data,correct preoperative diagnosis can be made in most cases.

目的 探讨非骨化性纤维瘤的x线表现以提高诊断水平。方法所有病例均摄有x线平片,分析经病理证实的8例非骨化性纤维瘤。结果临床症状轻,好发于下肢长骨干骺端或骨干,股骨4例,胫骨3例,肱骨1例。皮质型5例,表现为皮质内或紧贴皮质下的单层或多层透亮区,病变向骨内发展进入髓腔,周围有致密硬化带环绕,以髓腔侧明显;髓质型2例,病灶在骨内中央发展,显示为单房或多房透亮区,边缘有硬化,骨皮质菲薄,轻微向周围膨隆。结论 x线为最基本的检查方法,典型病例x线平片结合临床症状即可明确诊断。

RESULTS: Cortisol and adrenocorticotropic hormone measurementsdemonstrated effective manipulation of in vivo cortisol.

结果:皮质醇和促肾上腺皮质激素的测量证明有效控制体内皮质醇。

The posterior cingulated gyrus of patients with Alzheimers disease is impaired and the extent of damage should has a strong correlation with rCMRglc. The selective impairment might reflect the cortico-cortical and cortico-subcortical disconnections in the pathomechanism of Alzheimer's disease. DTI technique should be used to monitor the disease progression and as a surrogate marker for evaluation of drug efficacy in vivo.

AD患者表现为扣带回后部各向异性损害,且损害程度与葡萄糖代谢率呈负相关;这种损害反应了AD病理机制中皮质-皮质及皮质-皮质下联系的丢失;扣带回后部FA、MD值可以用来监测疾病的进展情况及评价AD治疗药物的临床疗效。

Expression of nNOS mRNA, eNOS mRNA and iNOS mRNA in the E 20 cerebral cortex: There were no obvious changes of expression of nNOS mRNA in ETU-injected and control groups. Expression of eNOS mRNA increased significantly in cerebral cortex of the encephalocoele group, And there were no obvious changes of expression of eNOS mRNA in cerebral cortex of the control group and the other ETU-injection groups.

六、不同组E20胎鼠大脑皮质中nNOS mRNA、eNOS mRNA和iNOS mRNA的表达 1、实时定量PCR检测发现对照组、给药无畸形组、脊柱裂组和脑膨出组E20胎鼠大脑皮质中nNOS mRNA表达无明显改变; 2、给药无畸形组、脊柱裂组和对照组胎鼠大脑皮质中eNOSmRNA表达无明显改变,而脑膨出组胎鼠大脑皮质中eNOS mRNA表达明显增多; 3、在各组未检测到iNOSmRNA表达。

Abstract] objective to discuss radiological findings of parosteal osteosarcoma on emphasis combined with clinical pathology and literature.methods 4 cases of parosteal osteosarcoma proved by operation and pathology were analyzed retrospectively.results female was 3 cases,male was 1 case,average age was 30.5 years old,these tumors were arised on posterior border of distal femur and popliteal cavity,presented as lobular dense ossified mass,defined lesion.one case had villose margin.a thin narrow lucent zone separated the mass from the cortex at two cases.one case underwent angiography,there was no malignant feature.conclusion parosteal osteosarcoma may be divided into low-grade type and high-grade type.radiological manifestations of early stage possess character,early diagnosis conduces to establish rational treating plan and evaluate prognosis.

目的 结合临床病理学特征和文献资料,重点讨论皮质旁骨肉瘤的x线特征。方法收集经手术、病理证实的皮质旁骨肉瘤病例4例,对其进行回顾性分析。结果 4例患者女3例,男1例,平均年龄30.5岁,肿瘤均发生于股骨远端后侧和腘窝处,表现为分叶状致密骨化肿块,边界清晰,其中1例边缘呈绒毛状改变,2例有细窄透亮带与骨皮质相隔,1例行血管造影,未见血管池等恶性征象。结论皮质旁骨肉瘤分为低度恶性和高度恶性两种,早期影像学表现有特征性,早期诊断有助于制订相应的治疗方案和评估预后。

Methods: Forty-four specimens of renal tissues were harvested from urolithic patients,control tissues were harvested from non-urolithic patients (6 specimens) and renal tumorpatients performing nephrectomy (21 specimens). Immunohistochemical technique wasestablished to study the location of VKORC1 in renal tissues. Western blot technique wasused to detect the differential expression of VKORC1 protein in renal tissues.

方法收集肾脏皮质组织标本71例,其中草酸钙结石组44例,对照组27例(肾盂输尿管交界处狭窄和输尿管结核组6例,皮质厚度小于1.0cm;肾肿瘤皮质组21例,皮质厚度大于1.0cm),应用免疫组织化学法检测VKORC1在组织中的表达部位,应用免疫印迹蛋白半定量法,检测各组VKORC1蛋白的表达,并分析其表达与肾脏积水及皮质厚度等因素的关系。

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I can still vividly recall the impressive scenes you gave. You were among my friends and relatives who accompanied me from my house to the seaport and when the porters were slow to show up, you obligingly carried my suitcase for me.

你对我的种种感人情意,使我记忆犹新,那天你随着我的亲友从家里送我上轮船,搬运工迟迟不来,你毅然替我提着皮箱上船。

St. Nicholas became the patron saint of Russia, where he was famous for his red cape, flowing white beard, and bishop's mitre.

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Long periods of seeming invincibility. Though some industries or lines of business exhibit characteristics that endow leaders with virtually insurmountable advantages, and that tend to establish Survival of the Fattest as almost a natural law, most do not. Thus, for every Inevitable, there are dozens of Impostors, companies now riding high but vulnerable to competitive attacks. Considering what it takes to be an Inevitable, Charlie and I recognize that we will never be able to come up with a Nifty Fifty or even a Twinkling Twenty. To the Inevitables in our portfolio, therefore, we add a few "Highly Probables."

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