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ConclusionGR mRNA upregulation in lung tissue could be one of the mechanism of glucocorticoid's effective cure for pulmonary fibrosis,and GR mRNA downregulation in lung tissue in renalyang asthenia syndrome could be one of cause of glucocorticoid's noneffective therapy for pulmonary fibrosis,in addition,the Chinese traditional medicine with warming Yang effect could be effective therapy for pulmonary fibrosis.

结论肺组织GRmRNA表达的上调是糖皮质激素防治肺纤维化之所以有效的机理之一,而肾阳虚状态下肺纤维化肺组织GRmRNA表达下调是临床上许多肺纤维化病人对糖皮质激素不敏感的原因之一,同时,温阳药也极可能具有防治肺纤维化的作用。

Brain injury in rat activated NF-κB for long time. During the first 1-2hours after injury, activated NF-κB existed mainly in axon, and then appeared inastrocyte in the next 24 hours, lasted for 1 year in pallium.

鼠脑损伤后可致NF-κB的长时间激活,创伤后1~2小时内,激活的NF-κB主要存在于轴突,在创伤24小时后激活的NF-κB主要存在于受伤皮质内的小神经细胞和星形胶质细胞内,这种激活可在脑皮质中至少持续1年。

Autoimmunity hypothesis of schizophrenia figures schizophrene has a certain degree of immunological functional disturbance,Hypothalmu- pituitary- adrenal axis can produceimmunosuppression. Hydrocortisone,the production of HPA axis,serve as important medium of immunosuppression, so we presume that hydrocortisone possibly induce immunological dysfunction of schizophrene.

精神分裂症的自身免疫假说认为精神分裂症患者存在一定程度的免疫功能低下,而下丘脑-垂体-肾上腺轴功能紊乱被认为是引起免疫抑制作用的主要机制之一,其中皮质醇是免疫抑制作用的重要介质,因此我们推测精神分裂症患者可能存在有皮质醇含量增高有关。

In the whole process of clinical observation, poor memory appeared the highest incidence, and hemiplegia, numbness and slightly purplish tongue were presented all the way round. 7. It was shown in the results of MRI data for the 23 cases in preserved Dongzhimen hospital that the brain lesions were distributed in cortex and the extensive structure of subcortex in the cases of motor aphasia after stroke.

7东直门医院留存的23例MRI图像数据叠加结果显示:卒中后运动性失语的脑损伤部位涉及到皮层及皮层下的广泛结构,以左侧基底节出现的频次最高,其次是颞叶皮质,再次是额、顶叶皮质,右侧基底节区也有损伤。

Using of matrix assisted laser desorption/ionization time of flight mass spectrometry coupled with carboxypeptidase Y digestion for the analysis of C terminal peptide ladder by direct determination of the mixture of truncated peptide, the sequence of C terminus can be read out simplely from the mass differences between adjacent peptide peaks on the mass spectrum.

用羧肽酶Y水解蛋白质和多肽,结合飞行时间质谱测定酶解后缩短肽的质量,根据相邻两肽峰的质量差别读出蛋白质和多肽的C端序列,在pmol水平下测定了人促肾上腺皮质激素片段以及人血管紧张肽片段,其中人促肾上腺皮质激素片段测到了C端 15个氨基酸残基的顺序

objective to study gastrodia elata blume to effect tau protein,sod,mda expression in gyrus hippocampi and cerebral cortex of experimental mice.methods to inject okadaic acid to mice ventriculus lateralis and to measure tau protein level,sod activity and lipid superoxide mda content of sod control group,oa injection group,oa and gastiodia elata injection solution group.results tau protein of experimental group(p<0.05/p>0.05),sod was lower than model group(p<0.001) and was higher than control group(p<0.05).conclusion gastrodia elata blume can increase sod activity and reduce tau protein expression and superoxide lipid forming in brain tissue of experimental dementia mice caused by oa.it can prevent and treat ad.

目的 观察天麻对痴呆模型大鼠海马、皮质神经元微管相关蛋白、超氧化物歧化酶和脂质过氧化物丙二醛表达的影响,探讨其治疗阿尔茨海默病(alzheimer disease,ad)的作用机制。方法用冈田酸(okadaic acid,oa)注射大鼠侧脑室造模,测定模型组、实验组、对照组海马和皮质tau蛋白、sod、mda的含量。结果实验组tau蛋白低于模型组(p<0.001),高于对照组(p<0.05);sod高于模型组(p<0.001)和对照组(p<0.05);mda低于模型组(p<0.001),高于对照组(p<0.05)。结论天麻可增强oa致实验性痴呆大鼠脑组织sod活性,降低mda蓄积和tau蛋白生成,具有防治阿尔茨海默病的作用。

The sexual sweat, but not the normal sweat, activated the right orbitofrontal cortex and the right fusiform cortex, brain areas that help us recognize emotions and perceive things, respectively.

女性的大脑中帮助我们了解情感和感知东西的右眶额皮质和右梭状皮质都对男性性致高时产生的汗液反应强烈,而对普通的含液就没有。

The regulatory effect of corticosteroids treatment on growth factors is mainly at early stage of tendon healing, but hyaluronic acid works at early and late stages. Corticosteroids always facilitate the expression of the growth factor, whereas hyaluronic acid not only promote but also inhibit the expression of growth factor.

皮质激素在肩袖损伤修复过程中对4种因子的调控主要在早期;透明质酸在修复早期、后期均有不同程度的作用;皮质激素的调控作用主要是促进生长因子的表达,而透明质酸存在双向调控作用。

because the sugar cortical hormone class medicine has very strong anti-function and so on inflammation, anti-allergy, antitoxin, anti-shock, immunity suppression, thus caused it to become the basic unit medical establishment certain doctors' multi-purpose panaceas, no matter any got sick all uses, thus created the sugar cortical hormone class medicine in basic unit abusing.light creates the nonessential pain and the economic loss for the basic unit patient; heavy endangers the patient life.

由于糖皮质激素类药物具有很强的抗炎、抗过敏、抗毒素、抗休克、免疫抑制等作用,因而使其成了基层医疗机构某些医生的万能灵丹妙药,不管什么病都用上,从而造成糖皮质激素类药物在基层的滥用。轻者给基层患者造成不必要的痛苦和经济损失;重者则危及病人生命。

Methods We detected the adrenocorticotropic hormone and cortisol in the 37 SARS patients from April to June 2003,through the radio-immunity examination in the 9th and 12th month after SARS onset,and investigated the correlation between the levels of plasma adrenocorticotropic hormone , serum cortisol and the glucocorticoid usage.

方法分别对2003年4月至6月天津武警医学院附属医院收治的37例SARS康复患者发病后9、12个月,使用放射免疫的方法随访检测SARS康复患者血浆中促肾上腺皮质激素及血清中皮质醇的质量浓度变化,并与25名正常人比较,观察与发病期间激素总量的关系。

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I can still vividly recall the impressive scenes you gave. You were among my friends and relatives who accompanied me from my house to the seaport and when the porters were slow to show up, you obligingly carried my suitcase for me.

你对我的种种感人情意,使我记忆犹新,那天你随着我的亲友从家里送我上轮船,搬运工迟迟不来,你毅然替我提着皮箱上船。

St. Nicholas became the patron saint of Russia, where he was famous for his red cape, flowing white beard, and bishop's mitre.

圣尼古拉成了俄罗斯人的守护神,在那里,他以身披红斗篷,留着飘逸的白胡须,戴着主教法冠而闻名。

Long periods of seeming invincibility. Though some industries or lines of business exhibit characteristics that endow leaders with virtually insurmountable advantages, and that tend to establish Survival of the Fattest as almost a natural law, most do not. Thus, for every Inevitable, there are dozens of Impostors, companies now riding high but vulnerable to competitive attacks. Considering what it takes to be an Inevitable, Charlie and I recognize that we will never be able to come up with a Nifty Fifty or even a Twinkling Twenty. To the Inevitables in our portfolio, therefore, we add a few "Highly Probables."

在所属的产业都被赋予其无可取代的优势地位,大者恒存的自然定律似乎牢不可破,但实际结果却不然,也因此在找到真正的真命天子之前,旁边可能还有好几打假冒者,这些公司虽然曾经红极一时,但却完全经不起竞争的考验,换个角度来看,既然能够被称为永恒的持股,查理跟我早就有心理准备,其数量绝对不可能超过五十家或甚至是不到二十家,所以就我们的投资组合来说,除了几家真正够格的公司之外,还有另外几家则是属于极有可能的潜在候选人。