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皮质激素

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Methods: fifteen sd rats were randomly divided into five groups (n=3), and adrenalectomy was performed and anterior pituitary specimens were obtained after a week. anti gap 43 antibody and anti adrenocorticotrophic hormone, thyroid stimulating hormone, luteinizing hormone, prolactin and growth hormone antibodies were used in the double immunohistochemical staining.

将成年雄性sd大鼠15只随机分为5组(n=3),手术切除大鼠双侧肾上腺,1 wk后取垂体前叶标本分别进行抗gap 43与抗促肾上腺皮质激素、促甲状腺激素、黄体生成素、催乳素、生长激素抗体的免疫组织化学双标染色,观察gap 43 li神经纤维与各腺细胞之间的关系。

AIM: To observe the effect of Nourishing Yin Antitoxic Capsule 2 (YC2) on the expression of glucocorticoid receptor proteins in Yin deficiency rats induced by hydrocortisone, and to investigate how the YC2 relieves the side effects of Glucocorticoid.

目的:观察养阴抗毒胶囊2号(YC2)对阴虚大鼠模型肝组织糖皮质激素受体蛋白表达的和对减轻激素副作用机理。

The concen-trations of these two componentes in ECM of decidua might be related by progesterone and corticosteroid.

早孕蜕膜组织中这两种ECM成分可能受孕激素及糖皮质激素的调控。

OBJECTIVE: To probe into the regulatory effects of CRH on CREB secretion in hypothalamic neurons.

目的:探讨促肾上腺皮质激素释放激素对下丘脑神经元内CREB含量变化的调节作用。

Results: The changes following hydrocortisone intervention of rats could be identified by PCA, and the kidney deficiency syndrome rats entered a state of "hyperfunction", involving a series of changes in metabolic pathway and metabolic network. The response integral area of lactic acid (δ 1.37) increased, indicating the accumulation of metabolites of lactic acid. The amount of dimethylamine (δ 2.72) also increased, indicating that the disorder of kidney function was related to kidney-deficiency syndrome. The response of creatinine (δ 3.87), asparaginic acid (δ 2.83), taurine (δ 3.44, 3.28), and hippurate (δ 7.84, 7.56, 7.64, 3.97) all decreased significantly, indicating that the hydrocortisone might cause adrenal cortex excretion injury. The response integral area of succinate (δ 2.41) and citric acid (δ 2.53, 2.68) decreased, which was usually caused by disorder of the mitochondrial function.

结果:PCA方法处理肾虚证和空白对照大鼠尿液数据显示,两组大鼠的数据可以在得分图实现分类,与对照组比较肾虚组大鼠由于氢化可的松诱导,大鼠机体进入一个过消耗后衰弱的状态,相关代谢发生显著变化,乳酸(δ 1.37)代谢发生堆积;二甲胺(δ 2.72)的含量增加,提示肾虚与肾功能异常是密切相关的;天冬氨酸(δ 2.83),牛磺酸(δ 3.44, 3.25),马尿酸(δ 7.84, 7.56, 7.64, 3.97),肌氨酸(δ 3.87)等的相对积分面积明显下降,这预示糖皮质激素可能引起了肾上腺皮质分泌功能的损害;琥珀酸(δ 2.41)和柠檬酸(δ 2.53, 2.68)是三羧酸循环能量代谢及糖酵解的中间产物,其含量的降低,通常是由于线粒体功能紊乱所引起。

There was no difference between the two groups withregard to plasmatic levels of norepinephrine, epinephrine, cortisol,or ACTH at any sample time, although the blood level of thesehormones significantly increased in each group with surgicalstimulation.

血中肾上腺素,去甲肾上腺素,皮质醇和促肾上腺皮质激素的值虽然由於手术刺激而增高,但是两组间没有差异。

Special attention is given to Cushing's disease (hypercortisolism secondary to an adrenocorticotropic hormone-secreting adenoma), acromegaly (secondary to a growth hormone-secreting adenoma), and hyperthyroidism in the setting of thyrotropic adenomas.

对于库兴综合症(肾上腺皮质激素分泌型腺瘤引起的皮质醇增多症)、肢端肥大症(生长激素分泌型腺瘤引起的)和促甲状腺腺瘤引起的甲状腺机能亢进我们要给于特别地注意。

Ouabain-LI chiefly exist in the zone reticularis of adrenal cortex of SD rat and Macaca mulattas. The morphological evidence shows that EO is a novel adrenocortical steroid hormone.

哇巴因免疫反应阳性物质主要存在于SD大鼠和恒河猴的肾上腺皮质网状带,为EO作为一种新的肾上腺皮质激素提供了形态学依据。

The cord blood levels of cortisal, adrenocorticotropic hormone, and dehydroepiandrosterone sulfate were measured by the radioimmunity technique in normal neonates immediately after birth.

在新生儿娩出后即刻收集脐静脉血,记录出生结局,并用放射免疫法检测脐血中皮质醇、促肾上腺皮质激素和硫酸脱氢表雄酮的含量。

Objective: To explore the difference of clinical features and biochemical indices of hypercortisolism among male and female patients with Cushing's disease. Methods: Eighty-one patients (56 females and 25 males)with CD were selected.

手术确诊的库欣病患者81例,根据性别分为男性组25例,女性组56例,比较2组临床症状、影像学检查结果,血、尿皮质醇,血促肾上腺皮质激素,小剂量(1 mg和/或2 mg)及大剂量(8 mg)地塞米松抑制试验的结果。

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曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。