皮脂瘤

Result:The content of cholesteatoma tissues and postauricular skin specimens are a normal euploid.

结果：胆脂瘤上皮细胞和外耳道上皮细胞的核型均为二倍体，未见异倍体。

Result of HE and special dye1.1 result of HE More cells are found in subsequent cholesteatoma. Cholesterol crystal, both sequestrum and neogenesis bone , gland metaplasia, Polykaryocyte are found in subepidermis of subsequent cholesteatoma.

结果1、HE染色结果：可见后天性胆脂瘤上皮的细胞层次增多，上皮内及上皮下有不同程度的急性、慢性炎细胞浸涧；上皮下有时可见胆固醇肉芽肿、死骨与新骨形成、腺体化生等病理改变。

Objective:To compare the DNA character with in cholesteatoma tissues with that in normal skin.

目的：采用流式细胞术分析胆脂瘤上皮细胞的DNA特征，探讨胆脂瘤的病理学属性。

Recent reports have shown that the inhibition of cholesteatoma epithelial cell apoptosis plays an important role in the formation and development of cholesteatoma.

最新研究表明胆脂瘤上皮细胞凋亡受到抑制在中耳胆脂瘤的发生和发展中起着重要作用。

Correlations between the above indexes and between the above indexes and the degree of ossicular destruction were investigated.

二者在胆脂瘤上皮的表达有一定的相关性，P＜0.05；与中耳胆脂瘤听小骨骨质破坏程度之间无明显相关性，P＞0.05。

HPV infection can arouse the cleavage and proliferation of cholesteatoma epithelium and may play certain role in the occurrence and development of middle ear cholesteatoma. Aggressive, papillomatous growth and koilocytes can be served as the initial proof of HPV infection in cholesteatoma of the middle ear.

HPV感染可能激发中耳胆脂瘤上皮的分裂增殖，在中耳胆脂瘤发生发展中起一定的作用；侵蚀性乳头瘤样生长和空晕细胞改变可以作为中耳胆脂瘤组织中HPV感染的病理学证据。

Result 1. CDK4, P16 were expressed in parabasal layers and the upper layer, mainly in the prickle and granular layers of cholesteatoma epithelium. Their positive rates were 68.6% and 88.6% respectively. Statistical analysis showed that there was a significant difference in positive rates between

CDK4与P16在中耳胆脂瘤上皮中均过度表达且有一定程度的正相关性，表明它们在疾病发生中是共同而非单独起作用的，从细胞周期的角度可反映胆脂瘤上皮细胞过度增殖的同时也增强负调控因子来抑制增殖，使凋亡同时加快而达到新的平

Result: CDK4 and P16 were expressed in parabasal layers and the upper layer, mainly in the prickle and granular layers of cholesteatoma epithelium.

CDK4与P16在中耳胆脂瘤发生中是共同而非单独起作用的，从细胞周期的角度可反映胆脂瘤上皮细胞过度增殖的同时也增强负调控因子来抑制增殖，使凋亡同时加快而达到新的平衡。

DNA content within 25 cholesteatoma tissues and 10 normal postauricular skin was measured with flow cytometry.

利用机械捣碎法将新鲜的胆脂瘤和外耳道上皮制成单细胞悬液；采用PI法，对25例胆脂瘤上皮和10例正常外耳道细胞上皮的DNA进行流式细胞术分析。

Middle ear cholesteatoma is destructive to auditory ossicles and temporal bone, and treatment usually requires surgical removal of all epithelial content.

中耳胆脂瘤在临床上对於中耳裂具有相当的破坏性，而治疗上通常必须藉手术清除中耳腔所有的胆脂瘤上皮成分。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。