皮肤静脉炎

MEBO was applied in treating 18 cases of skin injury and phlebitis caused by extravasation of drugs.

摘 要］目的：探讨临床化疗药物渗漏所致患者皮肤损害及静脉炎的有效治疗方法。

Such as inflammation of joints, the lower leg, such as chronic venous insufficiency lead to long-term sustainability of the skin caused by congestive hairy; hyperthyroidism in Pretibial myxedema patch Department often long acuminatum out; hypothyroidism and limbs of children in the back outside a large number of hair growth; children with viral encephalitis and inter-brain barrier after mumps-induced systemic hairy; head injury, especially after the children more prone to hair; children with primary malnutrition or enteropathy, or other malabsorption, or severe infections caused by malnutrition could rise to a large number of multi-body hair; anorexia nervosa patients in the face, trunk and upper limbs have more hair grow; infant limb pain patients in the limbs, face, trunk and more hair; dermatomyositis patients, mainly in children can be located hairy forearm, leg and temporal, but also a broader scope; Berordinelli syndrome, that is, growth and maturity accelerated from an early age, and accompanied by malnutrition and intestinal muscle atrophy, common hepatomegaly and high blood fat, the skin of patients with rough, often hairy; addition of certain drugs such as streptomycin, such as cortisone can cause iatrogenic hairy; some women as a result of adrenal, ovarian and other diseases caused by increased androgen can also result in more hair.

如炎症性关节，小腿慢性静脉机能不全等导致长期持续的皮肤充血造成多毛；甲状腺机能亢进者在胫前粘液性水肿的斑块处常有粗毛长出；甲状腺机能减退的儿童背部和四肢外侧有大量毛发生长；儿童在病毒性脑炎及流行性腮腺炎后间脑障碍所致的全身性多毛；头部外伤后特别是儿童易发生多毛；儿童原发性营养不良或肠病，或其他吸收不良，或严重感染引起的营养不良均可引起大量全身性多毛；神经性厌食症患者可在面部、躯干和上肢有较多的毛发长出；婴儿肢痛病患者可在四肢、面部、躯干部多毛；皮肌炎患者，主要发生于儿童中，多毛可位于前臂、小腿和颞部，但范围也更广泛；Berordinelli综合征，即生长和成熟从小就加速，并伴有肠营养不良和肌肉萎缩，常见肝肿大和高血脂，其患者皮肤粗糙，常多毛；此外某些药物如链霉素、可的松等可造成医源性多毛；某些妇女因肾上腺、卵巢等疾病致雄性激素增多也可造成多毛。

Only 3 cases found in the skin burns, there are 16 cases of phlebitis performance, 3 months, have returned to normal.

仅3例发现皮肤灼伤，16例有静脉炎表现，3个月都恢复正常。

Changes in Red Cell Enzyme Activity in Relation to Red Cell Survival in Infancy Antibody Deficiency Syndrome with Increased Gamma1 M(B2M) Globulins and Absent Gamma1 A(B2A) Globulins and Gamma2 Globulins. Needle Biopsy of the Liver in Various Forms of Childhood Tuberculosis Jaundice Associated with Severe Bacterial Infection in Young Infants Effectt of Hypoxia on Newborn Animals Renal Amyloidosis Resulting From a Chronically Infected Burn. Skin Testing of Allergic and Normal Children with Purified Milk Proteins. Pericarditis in Juvenile Rheumatoid Arthritis Cardiac Complication of Diphtheria Adenovirus Complement-fixing Titers from Birth through First Year Congenital Coronary A-V Fistula Narcotic and Methamphetamine Use During Pregnancy Purulent Pericarditis Transfer of Bilirubin-C^4 Across Monkey Placenta Plasma Antidiuretic Hormone in Nephrogenic Diabetes Insipidus Studies of Anabolic Steroids:Ⅰ.

红血球酵素活性度之变化与婴儿红血球生存期之关系 Gamma1 M(B2M)球蛋白增加而无Gamma1 A(B2A)球蛋白与Gamma2球蛋白之抗体缺乏症候羣儿童期各型结核病之肝藏针管活体切片检查幼儿细菌严重感染并发之黄疸缺氧对於新生动物之影响及其与肺玻璃膜病之关系烧伤处慢性感染引起之肾性淀粉样变性以精制奶粉蛋白对过敏症与正常小儿作皮肤试验年幼性类风湿性关节为合并的心包炎白喉之心脏合并症自出生至一岁之腺病毒补体结合滴定度先天性冠状动静脉瘻管怀孕时使用麻醉剂与Methamphetamine之结果化脓性心囊炎胆红素C^14标猴子胎盘之转送肾因性尿崩症患儿之血清抗利尿荷尔蒙之证明同化类固醇之研究Ⅰ。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

Chronic venous insufficiency can lead to skin discolouration, inflammatory dermatitis, recurrent or chronic cellulitis and ulceration.

下肢慢性静脉功能不全，可导致皮肤变色，炎症性皮肤炎，经常性或慢性蜂窝组织炎及溃疡。

Patients could discharged 3~5 days later. Long-term complication included shin numbness or paraesthesia, thrombophlebitis, residual varicose, recanalization of GSV.

随访211例，随访率86.5%，随访6个月至52个月，中远期并发症包括1、皮肤感觉异常、针刺或麻木感：8.6%(24/278)；2、皮下硬结合并血栓性静脉炎：12.6%(35/278)：3、局部曲张静脉残留或复发：6.8%(19/278)；4、大隐静脉再通：6.1%(17/278)。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。