皮肤肿瘤

Tumor associated protein n35 was located on the centriole of the chromosomal domain at the s-g2 phage.conclusions the tumor associated protein n35 might be a tumor cell growth regulator, expressed only it's the cancer cells and related with the proliferation of cancer cells.

结果 肿瘤相关蛋白n35不存在于正常人淋巴细胞、正常肺细胞及人皮肤纤维细胞中，而存在于肺癌细胞蛋白中，在亚细胞结构中主要分布于胞核，在肿瘤细胞有丝分裂进入g2至m期时明确地定位于中心粒结构上。

It distributed in the live lung cancer cell GLC-82, but not in the protein ingredient of the normal human lymphocyte, the normal human lung cell and human skin fibroblasts, Tumor associated protein N3S was located on the centriole of the chromosomal domain at the S-G2 phage.

结果：肿瘤相关蛋白N35不存在于正常肺细胞、人淋巴细胞及人皮肤纤维细胞中，而存在于肺癌细胞蛋白中，在亚细胞结构中主要分布于胞核，在肿瘤细胞有丝分裂进入S至G_2期时明确地定位于中心粒结构上。

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

MULBERRY ETHNOBOTANICAL USES has been proved in long human history as safe and effective medicine in numerical health conditions such of Antiphlogistic, Antitussive, Asthma, Bactericide, Bronchitis, Cachexia, Circulation, Cold, Cough, Edema, Emollient, Expectorant, Fever, Hair-Tonic, Hair black Hyperglycemia, Hypertension, Inflammation, Insomnia, Intestine, Laxative, Melancholy, Nervine, Neurasthenia, Ophthalmia, Pectoral, Perspiration, Phthisis, Preventitive, Psoriasis, Purgative, Roborant, Sedative, Senility, Skin, Sore, Stomatitis, Thirst, Throat, Tonic, Tumor, Tumor, Vertigo, Wound.

桑树利用民族植物学人类历史已证明安全有效长医药卫生等条件的数值消炎、止咳、哮喘、杀菌剂、支气管炎、恶、流通、冷、咳嗽、水肿、润肤、祛痰、发烧、毛发补品、黑头发高血糖、高血压、炎症、失眠、小肠、泻药、忧郁、nervine、神经衰弱、结膜炎、胸肌、排汗、肺病、preventitive，银屑病、泻、健壮、镇静、衰老、皮肤疮口腔炎、口渴、喉咙、补品、肿瘤、肿瘤、眩晕、伤口。

Topical application of cold substances to tumors was first reportedin treatment of superficial tumors of skin, oropharynx and gynecologic systems.

最早对肿瘤局部应用制冷物质的报道是对浅表皮肤，口咽部，和妇科肿瘤进行的治疗。

These indicates bioactive peptides in Chinese forest frog skins have great potential for the exploitation and utilization. S_(180) cells were inoculated hypodermically at the concentration of 1×10~6 cells per mouse and the bioactive peptides in Chinese forest frog skins were resolved into aseptically distilled water to make injection liquid. After injected continuously 15 days, the inhibition rate of tumor was calculated. The induction of tumor cell apoptosis of active peptides in Chinese forest frog skins could be detected by morphological

将S_(180)胃肉瘤细胞接种至小鼠皮下，选取中国林蛙皮肤生物活性肽不同浓度样品液，连续注射种瘤小鼠15天后，计算抑瘤率；采用透射电镜观察细胞形态学变化、DNA梯度琼脂糖凝胶电泳技术、MTT比色法、流式细胞检测等技术观察中国林蛙皮肤生物活性肽对K562肿瘤细胞凋亡过程的诱导。

As it is also helpful in observing vascular structures that are invisible to naked eyes, dermoscopy has been applied for the differential diagnosis of some nonpigmented skin disorders, including tumors, inflammatory and infectious diseases.

由于皮肤镜可以显示肉眼观察不到的血管等结构，近年来皮肤镜技术正被越来越多地应用于非色素性疾病，包括肿瘤、炎症及感染性疾病的鉴别诊断。

Several terms, such as cutaneous collision tumor, cutaneous mixed tumor and biphasic sarcomatoid carcinoma have been described.

其他如皮肤碰撞性或混合性肿瘤或是双相性类肉瘤性癌都曾被提出来描述此类肿瘤。

After HOM-Mel-40 was serologically identified as a tumor associated antigen from melanoma patients, it confirmed that cancer patients contained immunity against their own tumors.

自从HOM-Mel-40抗原在皮肤黑色素瘤的病患中，以血清学方法被鉴定为肿瘤相关抗原之后，更加肯定在癌症病人体内具有对抗自体肿瘤的免疫力。

In an in vivo tumor model, direct MSC inoculation into subcutaneous melanomas induced apoptosis and abrogated tumor growth.

在活体肿瘤模型中，直接接种MSC到皮肤黑色素瘤中诱导细胞凋亡和抑制肿瘤的生长。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。