皮肤形成

Algin, Atelocollagen, Serine film can form a layer of moisture, increasing skin moisture degrees, to maintain long-lasting skin moisturizing effect, improving the skin is not easy on the makeup Fufen phenomenon.

Algin， Atelocollagen， Serine能形成一层保湿膜，增加肌肤含水度，维持皮肤长效保湿效果，改善肌肤不易上妆、浮粉的现象。

It is rich in a variety of amino acids and vitamins necessary to humans, has with its close relatives - the same aloe cosmetic results, as well as prevention of constipation, the promotion of eye health care, increase bone density, helping to form cell membranes, prevent anemia and anti-neuritis , angular cheilitis, lower cholesterol, skin whitening anti-black spot, lift the heavy metal poisoning, anti-free radical, anti-old age disease, inhibit tumor and other effects, is one of the human ideal health food.

它富含多种氨基酸和人体必需的维生素，有着与它的近亲--芦荟相同的美容效果，还有预防便秘、促进眼睛保健、增加骨质密度、帮助细胞膜形成、预防贫血和抗神经炎、口角炎、降低胆固醇、皮肤美白防黑斑、解除重金属中毒、抗自由基、防老年病变、抑制肿瘤等多种功效，是人类理想的保健食品之一。

Objective To explore the effect of sodium arsenite(NaAsO2) on antioxidative ability in human keratinocytes.

目的 研究亚砷酸钠(NaAsO2)对人皮肤角质形成细胞抗氧化能力的影响。

Arterialization of the outflow venous system may induce this condition, and result in impairment of arteriovenous access function, disabling upper extremity edema, violaceous discoloration and hyperpigmentation, ulceration of the skin, and in advanced cases, gangrene formation of the fingers and neuralgia.

原因可由前臂与手掌回流静脉产生动脉化而造成，同时动静脉管失去透析功能，上肢肿胀呈蓝紫色或色素沈著的变化，有时会形成皮肤溃疡，在严重的病例甚至会造成手指坏疽变化与神经痛。

The product has passed the test of National Institute for the Control of Pharmaceutical and Biological Products and is about to get clinic use certification. The product has many advantages such as perfect physical characteristics, biotical compatibility, safety, accelerating wound healing, simplifying operation, having the antibacterial ability and etc.

已形成稳定的生产技术路线，已通过国家检测，即将获得临床试用批文，进入临床观察试验阶段，是目前唯一一个具有自主抗感染能力的组织工程皮肤产品，物理特性好，生物相容性好，安全性高，能够覆盖创面，促进伤口愈合。

Results 8 days after intracutaneous injection,fully developed pigmented hair follicle formed.2 weeks later,skin surface of injection site became black and evlevated, a grey sac formed lined with keratinized epithelium,lots of hair follicles formed with black hair shafts and fully developed sebaceous glands.

结果皮内移植后8天可见有完整的黑色毛囊形成，2周见移植区皮肤呈黑色隆起，移植物形成一个灰白色囊，内衬角化上皮，周围见大量新生毛囊及黑色毛干，新生毛囊呈向心性排列，伴发育良好的皮脂腺。

The mesenchyma stem cell is the multi-potential stem cell, and become the important seed cells in skin tissue engineering due to its unique biology characteristics.

组织工程化皮肤的血管构建技术涉及多个方面，如接种血管形成的种子细胞，进而促进血管结构的形成。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

One solution to the deficiency problem is the vitamin D supplement - but how much can we safely take without overdosing and risking liver damage?

一次形成在皮肤之下形成的维生素D通过激活它的肝脏和肾脏。然后搬入它控制钙的水平下进而进入身体组织和血液细胞。

At skin sites destined to have apocrine units, a third epithelial bud develops from the opposite side of the follicle above the level of the sebaceous gland anlage.

在形成顶泌汗腺单位的皮肤部位还有第三个上皮胚芽形成，它发生于皮脂腺始基之上与毛囊相对的位置。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。