皮硬化病

Radiographic signs of the disease are increase in density of bilateral bones, osteosclerosis with thickening of the cortex and stricture or obliteration of the medull...

本病的X线征为双侧骨骼的密度增高和骨质硬化，骨皮质变厚，骨髓腔变窄甚至闭塞。

However, overall, a lobulated architecture is preserved.

所以，形态学特点是符合乳头部腺瘤伴有旺炽上皮增生和硬化性腺病改变的。

In this review data on the use of rituximab is presented from 92 studies involving 1197 patients with the following diseases: systemic lupus erythematosus, idiopathic thrombocytopenic purpura, anti-neutrophil cytoplasmic antibody associated vasculitis, Grave's disease, autoimmune hemolytic anemia, pemphigus vulgaris, hemophilia A, cold agglutinin disease, Sjogren's syndrome, graft vs. host disease, thrombotic thrombocytopenic purpura, cryoglobulinemia, IgM mediated neuropathy, multiple sclerosis, neuromyelitis optica, idiopathic membranous nephropathy, dermatomyositis, and opsoclonus myoclonus.

本综述资料总结了92项共1197例患者应用利妥昔的研究，包括系统性红斑狼疮、特发性血栓性血小板减少性紫癜，抗中性粒细胞抗体相关性血管炎、甲状腺功能亢进、自身免疫性溶血性贫血、寻常型天疱疮、甲型血友病、冷凝集素病、干燥综合征、移植抗宿主疾病、血栓性血小板减少性紫癜、IgM介导性神经病、多发性硬化、视神经脊髓炎、特发性膜性肾病、皮肌炎和眼肌阵挛性肌阵挛。

Imageological methods, such as ultrasound and molybdenum tarsget are not sensitive for the diagnosis of breast sclerosing adenosis. IHC staining of myoepithelium is an important for the diagnosis of breast sclerosing adenosis demarcated with breast cancer. Non-palpable lesion of breast sclerosing adenosis can be surgically exsected with the guide wire localization under molybdenum target.

B超、钼靶等影像学方法对于诊断硬化性腺病的敏感性较差；免疫组化染色肌上皮标记SMA、P63是鉴别乳腺硬化性腺病与乳腺癌的重要指标；对于不能触及病变的硬化性腺病可采用钼靶摄片下钢丝定位后外科切除。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。