皮真菌病

Blastomycosis is a fungal disease caused by Blastomyces dermatitidis that affects both dogs and humans.

芽生菌病是一种真菌感染性疾病，由皮炎芽生菌引起，为人犬共患病。

A preparation that is derived from a culture of the fungus Blastomyces dermatitidis and is injected intracutaneously as a diagnostic test for blastomycosis.

芽生霉素从皮炎芽生菌真菌的培养中获得的制剂，作为芽生菌病的皮内诊治

In 21 cases of hand dermatitis the aeroallergen role was investigated with, serv-ing as a control,21 cases of urticaria,11 cases of eczema and 8 cases of dermatomycosis,In con-trast to urticaria,eczema and dermatomycosis,the result displayed a·significant increase of thepositive rates and an enlarged wheal diameter for polyvalent mold II and polyvalent in-sects(P.05,P.01)in hand dermatitis .

对21例手部皮炎患者进行了吸入变应原的研究，以21例荨麻疹、11例湿疹、8例皮肤癣病作为对照。结果发现手部皮炎与荨麻疹、湿疹、表皮癣菌病相比，多价真菌Ⅱ、多价昆虫变应原阳性率明显增高

And 25.3%(419/1653 ) of canine clinical cases are caused by these diseases. The occurrence of canine ectoparasite disease and dermatosis depends on dog"s breeds and age, the local climate, physical environment around the dog field, dog"s breeding and management, dogs self-immunity ability, and so on.

调查发现，2001年该犬场主要存在犬虱侵染、犬蜱侵染、犬疥螨病、犬蠕形螨病、犬真菌性皮肤病、犬湿疹和犬化脓性皮炎7种体外寄生虫和皮肤病，占疾病总发生率的25.3％(419／1653)。

Methods One hundred and fifty strains of Malassezia yeasts from pityriasis versicolor (29 strains), Malassezia folliculitis (16 strains), seborrheic dermatitis (49 strains), onychomycosis (33 strains), and healthy individuals(23 strains) were studied, according to physiological and morphological features in culture, and compared to standard strains.

方法以标准株作对照，用生理生化学及形态学方法将150株来源于花斑癣（29株）、马拉色菌毛囊炎（16株）、脂溢性皮炎（49株）、甲真菌病（33株）及正常人皮肤（23株）的马拉色菌进行分类及描述，并分析了各菌种在一些皮肤病的分布情况。

Indications: for quick treatment of localized mycosis, dermatophytes, Athlete's foot, Candidiasis, Fungal Infection, Labial moniliasis, Vulvitis, genital, anal and peri-anal mushrooms, Erythrasma, Ingrown and nail Fungal infection

适应症：快速治疗局部霉菌病、皮霉菌、运动员脚、念珠菌、真菌皮肤感染、唇念珠菌病、外阴炎、生殖器、肛门及肛门周围蘑菇形增生。红藓，指甲长入肌肉以及指甲霉菌感染。

MTT assay FAK signaling pathway inhibitor genistein on human corneal epithelial cell cytotoxicity;RT-PCR detection of human corneal epithelial cells adhesion to fungus at different times,extracellular matrix protein including laminin,fibronectin,FN glass,Ⅳcollagen,transmembrane protein integrinαⅤ,integrinβ1(ITGβ1),as well as the FAK signaling pathway FAK1,FAK2 and Paxillin gene expression;Western blot detection of the signal transduction pathway adhesion-associated protein ITGβ1,FAK and PAX expression and the inhibition of genistein. Immunocytochemical method was used to observe the LN,FN and FAK expression in human corneal epithelial cells during interaction with the fungues;Laser scanning confocal microscope had a cell positioning on FN,FAK and PAX,observed the changing of the human corneal epithelial cytoskeleton after stimulated by fungues;Quantitatived by flow cytometry to detect of human corneal epithelial cells with PAX at ITGβ1 fungal expression after adhesion;Optical microscopy quantitied the fungues and human corneal epithelial cell adhesion and recorded to determination the integral optical density afrer adhesion;Scanning and transmitted electron microscope observed the changing of cell ultrastructure after fungues and human corneal epithelial cell adhesion.

第一部分真菌激活人角膜上皮细胞FAK信号转导通路的体外实验研究将三种常见致病真菌(白色念珠菌、烟曲霉菌和茄病镰刀菌)分别与人角膜上皮细胞共孵育，MTT法检测FAK信号通路抑制剂染料木黄酮的对人角膜上皮细胞的细胞毒性作用；RT-PCR检测真菌黏附人角膜上皮细胞后不同时间细胞外基质层连蛋白、纤连蛋白、玻连蛋白、Ⅳ型胶原、跨膜蛋白整合素αV、整合素β1(ITGβ1)，以及FAK信号通路中FAK1、FAK2和桩蛋白基因的表达情况；Western blot的方法检测黏附信号转导途径相关蛋白ITGβ1、FAK和PAX的表达，以及染料木黄酮对真菌刺激人角膜上皮细胞FAK信息通路活化的抑制作用；免疫细胞化学方法观察人角膜上皮细胞与真菌相互作用过程中LN、FN和FAK的表达；激光共聚焦显微镜对FN、FAK和PAX进行了细胞定位，并观察真菌刺激后人角膜上皮细胞骨架的变化；流式细胞仪定量检测人角膜上皮细胞ITGβ1与PAX在真菌黏附后表达的改变；光学显微镜观察真菌与人角膜上皮细胞黏附数量，记录并测定了黏附后积分光密度值OD扫描及投射电镜观察了真菌与人角膜上皮细胞黏附后，细胞超微结构的改变。

These include a bacterial infection called Pierce 's disease , fungal infections such as mildews and rots , and viral diseases such as grape fanleaf virus and corky bark .

地，比如细菌致病的皮尔斯病，真菌感染的霉病和腐败，以及病毒性疾病如圆叶病毒和树皮干枯等。

The reason is that the state is home to diseases that clobber wine grapes. These include a bacterial infection called Pierce's disease, fungal infections such as mildews and rots, and viral diseases such as grape fanleaf virus and corky bark.

原因在于，这个州是葡萄树多种疾病的发源地，比如细菌致病的皮尔斯病，真菌感染的霉病和腐败，以及病毒性疾病如圆叶病毒和树皮干枯等。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！