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The HPLC method is simple, accurate and reproducible, and it can be used for the quality control standard of paeonol in Compound Cortex Moutan Decoction.

运用高效液相色谱法检测复方丹皮汤中丹皮酚的含量简便、准确、重复性好,可作为复方丹皮汤的一种质量控制方法。

Study on the Effect of Azone on Percutaneous Absorption of Clindamycin Hydrochloride in Cream;2. OBJECTIVE To observe the effects of three transdermal enhancers( azone ,isopropyl myristate,oleic acid) in vitro under the condition of iontophoresis with diclofenac sodium as the model drug.

方法选择聚乙烯醇、聚乙烯吡咯烷酮、羟丙甲基纤维素为基质,制备了分别含有月桂氮酮、肉豆蔻酸异丙酯和油酸的双氯芬酸钠经皮离子导入凝胶,采用改良Franz纵向释放池,以人体皮肤为透皮屏障,进行药物凝胶的离子导入经皮试验。

In the preformulation study, the ultraviolet spectrum and HPLC methods for the assay of α-asarone were established firstly and then the physicochemical properties, especially the octanol/water partition coefficient and the solubility in various solvent systems such as alcohol, PEG 400, IPM, octanol were examined. The prediction permeability was then compared with actual transdermal parameters obtained from the in-vitro diffusion study , and feasibility of drug transdermal absorption was then analyzed.

在制剂开发的处方前研究工作中,首先建立了α-细辛醚的紫外及HPLC分析方法,测定了药物的油水分配系数及在生理盐水、各系列浓度的乙醇、PEG400、肉豆蔻酸异丙酯、正辛醇等溶媒中溶解度;其次,确立了药物体外经皮渗透研究的方法,并考察溶媒及促渗剂(乙醇、丙二醇、肉豆蔻酸异丙酯等)对药物体外经皮渗透性能的影响,计算药物经皮渗透的各参数,根据药物的药物动力学参数,分析了药物经皮吸收的可行性。

ConclusionThe content of quercitroside in different preparations varies with temperature. Quercitroside in the carbon is decompounded partially to be quercetin which enhances possibly the hemostatic effect.

结论随着炮制温度的升高,槲皮苷的含量逐渐减少;炒炭后止血作用增强,推测与炭品中槲皮苷部分分解生成槲皮素有关。

Results: in contrast with model group, SSM can (1) increase the survival rate of ARF in rats, cut down Scr and BUN at 24hr, improve renal function, slightly surpass Vp in its therapeutic effect;(2) mitigate the extent of renal pathologicchanges, decrease the numbers of renal tubule necroses and casts;(3) protect renal ultrastructure such as microvilli, mitochondria, endoplasmic reticulum of TEC, podocytic process of glomerulus epithelial cell,endothelial cell etc, better than Vp;(4) enhance SOD activity, lower MDA contents in renal cortex;(5) enhance NO contents in serum, reduce ET levels in plasma;(6) evidently cut down TNF- a contents in serum, superior to Vp;(7) antagonize calcium overload in TEC;(8) alleviate renal pathological changes in ARF metaphase (at 3d), advance regeneration and recovery of TEC, restore renal structure in ARF convalescence (at 5d), and better than Vp;(9) increase the expression of TEC PCNA and prepro EGFmRNA in ARF metaphase.

结果:与模型组相比,SSM能(1)提高ARF大鼠的存活率,降低24hr时Scr及BUN,改善肾功能,其疗效略优于维拉帕米;(2)减轻ARF肾脏病变程度,减少24hr肾小管坏死数及管腔内管型数;(3)对肾脏的超微结构如肾小管上皮细胞微绒毛、线粒体、内质网、肾小球上皮细胞足突、内皮细胞等形态结构均有一定的保护作用,其疗效略优于维拉帕米;(4)提高肾皮质SOD活性,降低MDA含量;(5)提高血清NO水平,同时降低血浆ET含量;(6)显著降低血清TNF-α的水平,疗效明显优于维拉帕米;(7)拮抗小管上皮细胞[Ca~(2+)]_i的升高;(8)使ARF中期(第3d时)肾组织病变较同期其它两组明显减轻,并使肾小管细胞再生修复提前,至ARF恢复期(第5d时)肾组织结构恢复重建良好;作用明显优于维拉帕米;(9)促进ARF中期肾小管上皮细胞PCNA的表达及EGF前体mRNA的合成,从而增加EGF的合成释放,而维拉帕米无此作用。

After years of unremitting efforts, we have initially developed with the combination of tradition and the technology the Crispy Three-flavored Fruit Fudge, Crispy Chocolate Fudge, Crispy Corn Fudge, Dry Milk Sticks and many other independent products which won the favor of vast consumers once launched.

经过多年不懈努力,传统与技术结合自行开发了脆皮三味果软糖、脆皮巧克力软糖、脆皮玉米软糖、干吃奶棒、等多款自主产品,一经上市就受到了广大消费者的喜爱。我们一直抱着技术求精、质量求严、作风求实、经营求信,提倡优良服务,满足各大客户的需求,树造名牌形象。

By using standard addition method and standard curve method, the quantity of aesculin in Cortex Fraxini was determined to be 0.10% and the aesculetin was 0.36%, respectively.

利用标准曲线法和标准加入法对秦皮药材中秦皮甲素的含量进行测定,结果为0.10%,对秦皮乙素的测定结果为0.36%。

According to the fluorescence differences of aesculin and aesculetin at different pH values, a fluorescence method was developed for the determination of aesculin and aesculetin in Cortex Fraxini.

利用秦皮甲素和秦皮乙素在不同pH条件下荧光性质的差异性,制定了秦皮药材中二者分别测定的荧光分析方法。

A soft, grayish-yellow leather usually having a suede finish, once made from deerskins but now generally made from sheepskins.

鹿皮一种柔软的,黄灰色的革,常有一层麂皮抛光,以前多由鹿皮制成,但现在多由羊皮制成

Itplayed a role in the morphogenesis and ductal migration of mammary epithelial cells, promoted theresponsiveness of these cells to lactogenic hormones in vitro and induced the differentiation ofmammary epithelium into secretory lobuloalveoli.

Heregulin-α是细胞间信号蛋白,它可增强体外培养的乳腺上皮细胞对催乳素的敏感性,在乳腺上皮细胞形态发生、导管形成,以及诱导乳腺上皮细胞分化成分泌腺泡中扮演了重要角色,对乳腺发育和乳腺功能调控具有重要作用。

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。