皮炎

Methods: We searched the data base of National Taiwan University Hospital between 1989 and 2006 for DM/PM patients with ILD. The medical records were reviewed.

我们搜寻台大医院资料库中，从西元1989年到2006年中符合皮肌炎或多发性肌炎并发间质性肺炎的病例，并分析其病历。

Inflammatory model of Kunming mice ear edema induced by croton oil and determination combined with the LC-MS-MS-guided fractionation and isolation were used.

以巴豆油引起小鼠耳肿胀模型做为抗炎筛选模型，同时，在LC-MS-MS分析的导向下，寻找合欢皮抗炎活性部位。

Cutaneous infections in dogs, including skin fold pyoderma impetigo, folliculitis, furunculosis and cellulitis.

的犬，包括皮肤皱褶皮肤感染性脓皮病脓疱疮，毛囊炎，疖和蜂窝组织炎。

Tru-cut specimens of thyroid tissue from 37 cases of autoimmune thyroiditis, 23 cases of hyperthyroidism and 13 cases of thyrotoxicosis with thyroiditis were analyzed by immunohistochemistry using monodonal antibody specific for HIA-DR antigen.

本文应用单克隆抗体及免疫组化技术对37例自身免疫性甲状腺炎，23例甲亢及13例甲亢伴甲状腺炎甲状腺上皮细胞DR抗原异常表达进行原位研究。

Methods The acute edematous pancreatitis and hemorrhagic necrotizing pancreatitis model of rats were induced by cerulein and dextran-110 and endothelin-1 was administered on AEP rats via intravenous injection. Serum amylase, plasma ET and 6-Keto-PGF1α, pancreas hostologic observation were determined.

应用蛙皮素及高分子右旋糖酐造成大鼠急性水肿性和出血坏死性胰腺炎模型，观察血浆内皮素水平及其它相关指标，同时观察外源性内皮素对水肿性胰腺炎大鼠血清淀粉酶、6-Keto-PGF1α及胰腺组织病理形态等的影响。

Mirror infiltrating the cancer vagina the image is that the blood vessel is abnormal mainly,original place cancer vagina mirror visible image acetic acid white epithellum,major partners the shape blood vessei,heterotype blood vessel,mosaic and floccosoids wait a little bit;CIN acetic acid white maximum appears on epithelium,the shape blood vessel,heterotype blood vessel,rnosaic and floccosoids take second place;The chronic cervicitis gives first place to no representative shape blood vessel China and acetic acid white epithelium.

浸润癌阴道镜图像主要是血管异常，原位癌阴道镜图像可见醋酸白色上皮，伴有点状血管、异型血管、镶嵌和白斑等；CIN醋酸白色上皮出现最多，点状血管、异型血管、镶嵌和白斑次之；慢性宫颈炎以不典型点状血管和醋酸白色上皮为主。

Results Among 4913 TRUST tests,57 occur the biological false positive reactions,the most occur the lepra,about 31.82% of the lepra patients,secondly RA 17.78%;systemic LE 17.02%,hepatitis 5.43%,scleroderma 3.33%,dermatomyositis 3.13%,activity tuberculosis 1.82%.

结果 4913例TRUST试验，57例发生生物学假阳性反应，麻风发生率最高，占麻风病例的31.82%，依次为类风湿关节炎17.78%，系统性红斑狼疮17.02%，变应性血管炎6.67%，乙型肝炎5.43%，硬皮病3.33%，皮肌炎3.13%，活动性肺结核1.82%，孕妇0.68%，正常人0.08%。

Results Among 4913 TRUST tests,57 occur the biological false positive reactions,the most occur the lepra,about 31.82% of the lepra patients,secondly RA 17.78%;systemic LE 17.02%,hepatitis 5.43%,scleroderma 3.33%,dermatomyositis 3.13%,activity tuberculosis 1.82%.

结果 4913例TRUST试验，57例发生生物学假阳性反应，麻风发生率最高，占麻风病例的31.82%，依次类风湿关节炎17.78%，系统性红斑狼疮17.02%，变应性血管炎6.67%，乙型肝炎5.43%，硬皮病3.33%，皮肌炎3.13%，活动性肺结核1.82%，孕妇0.68%，正常人0.08%。

Objective To investigate the effect of Artesunate on experimental immune myositis animal model.

目的 建立类似于人类多发性肌炎/皮肌炎的豚鼠模型，观察青蒿琥酯对此模型的影响。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。