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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

Methods: The effect of IL-1 and interleukin-1 receptor antagonist (IL -1ra) injected icv.on behavior and EEG of cortex and hippocampus were observed in rats with seizure induced by pentylenetetrazol.

采用记录脑电图同时观察行为的方法,观察IL-1β和IL-1受体拮抗剂(IL-1ra)侧脑室注射对戊四氮致痫大鼠行为和皮层、海马EEG的影响。

Methods Wistar middle cerebral artery occlusion reperfusion rat model was established by thread ligation. The infarction focus formation was observed by TTC staining. AIF expression in ischemia region of cortex of parietal lobe and nerve cell apoptosis degree in sham operation group, MCAO 90 min and reperfusion 0, 3, 6, 12, 24, 48 and 72 h were observed by TUNEL and immunohistochemistry technique.

应用线栓法建立Wistar大鼠大脑中动脉阻塞再灌注模型,TTC染色观察梗死灶的形成,应用原位末端标记和免疫组化技术分别观察大鼠假手术组、MCAO 90 min再灌注0、3、6、12、24、48、72 h时额顶叶皮层缺血脑区AIF表达及神经细胞凋亡程度的变化。

Dramatic response in the central part of the occipital lobe, which was related to white light stimuli, located at primary visual cortex. Response area in bilateral Broadaman 19 areas was related to vision-motion function.

枕叶中央区域的强烈反应位于初级视觉皮层区,与白光刺激有关;两侧19区的反应与视觉运动功能有关。

PROF.: When he began his research in the 1980s, neurologists knew that the monkey's

当他在80 年代开始研究的时候,神经学家已经知道猴子的视觉皮层由

Experiment five explored the differences of gray matter concentration between the two groups.

实验五通过脑结构像考察了两组被试的脑皮层灰质密度之间的差异。

After feeding a nother 3 days in different environments with normal diet, all animals were killed and cGMP level and NOS expression were analysed in retina and retinogenicualte.Results:The NOS expression and cGMP contents of photoreceptor cells, vi sual cortex and retinogeniculate were increased in dark adaptation group compar ed with light group.

结果:在暗适应条件下,视网膜光感受体细胞NOS表达,视皮层、外侧膝状体、顶盖前区或海马cGMP含量增加,而在明适应状态下,NDP组化染色浅淡,牛磺酸及微量营养素的干预则能明显增强暗适应条件下NOS的着色反应,增加光照及暗适应条件下上述脑功能区cGMP含量。

After feeding a nother 3 days in different environments with normal diet, all animals were killed and cGMP level and NOS expression were analysed in retina and retinogenicualte.Results:The NOS expression and cGMP contents of photoreceptor cells, vi sual cortex and retinogeniculate were increased in dark adaptation group compar ed with light group. Nutritional intervention could enhance the NOS staining in dark environment, increased the cGMP contents whether light or dark condition.

结果:在暗适应条件下,视网膜光感受体细胞NOS表达,视皮层、外侧膝状体、顶盖前区或海马cGMP含量增加,而在明适应状态下,NDP组化染色浅淡,牛磺酸及微量营养素的干预则能明显增强暗适应条件下NOS的着色反应,增加光照及暗适应条件下上述脑功能区cGMP含量。

In addition, mitochondria isolated from the injured cortex at 3 or 6 h post-injury demonstrated that treatment with the uncouplers significantly improed seeral parameters of mitochondrial bioenergetics.

此外,在损伤后3或6小时损伤皮层分离出的线粒体表明运用解耦联剂治疗可显著改善线粒体生物学能量的参数。

Objective To investigate relationship between GHBA's protective effect on hypoxia-reoxygenation neuronal damage and GABA and GABARα1 positive neurons.

目的 探讨γ-羟基丁酸对大鼠皮层神经元缺氧复氧损伤的保护作用与γ-氨基丁酸和GABA受体A型α1亚型GABA(下标 ARα1阳性神经元表达的关系。

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I can still vividly recall the impressive scenes you gave. You were among my friends and relatives who accompanied me from my house to the seaport and when the porters were slow to show up, you obligingly carried my suitcase for me.

你对我的种种感人情意,使我记忆犹新,那天你随着我的亲友从家里送我上轮船,搬运工迟迟不来,你毅然替我提着皮箱上船。

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Long periods of seeming invincibility. Though some industries or lines of business exhibit characteristics that endow leaders with virtually insurmountable advantages, and that tend to establish Survival of the Fattest as almost a natural law, most do not. Thus, for every Inevitable, there are dozens of Impostors, companies now riding high but vulnerable to competitive attacks. Considering what it takes to be an Inevitable, Charlie and I recognize that we will never be able to come up with a Nifty Fifty or even a Twinkling Twenty. To the Inevitables in our portfolio, therefore, we add a few "Highly Probables."

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