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We investigated constituent of triterpenoid saponins ofAlbizzia, two new compounds together with two known compounds were isolated from Albizzia julibrissin Durazz. by using column chromatography (macroreticular resin, silica gel, Sephadex gel, reverse phase silica gel),preparative HPLC methods et al.On the basis of spectroscopic analysis, including IR,ESI-MS,~1H-NMR,~(13)C-NMR,HMBC,HMQC,~1H-~1HCOSY and chemical methods, the structure of two new compounds were identified as 3 - O -[β-D-xylopyranosyl(1→2)-β-D-fucopyranosyl (1→6)-β- D -2- deoxy - 2 - acetoamidoglucopyranosyl] -21-O-[(6S)-2- trans- 2,6-dimethyl - 6 - O-β- D - quinovopyranosyl -2,7- octadienoyl] - acacic acid- 28 - O-β-D-glucopyranosyl(1→3)[α-L-arabinofuranosyl(1→4)]-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside acacic acid 3- O -β- D- glucopyranosy(1→3)-β- D- fucopyranosl(1→6) [β-D- xylopyranosyl (1→2)]-β-D-glucopyranoside ;two known compounds were acacic acid lactone 3- O -β-D- xylopyranosyl-(1→2)-β-D-fucopyranosl (1→6)- 2-deoxy -2 -acetoamido -β-D- glucopyranoside ; acacic acid lactone 3- O-β-D-xylopyranosyl(1→2)-α-L- arabinopyranosl (1→6)- 2- deoxy - 2- acetoamido -β-D-glucopyranoside . The study lays chemical foundation and chemical reference substance for enhancing quality standard of Albizzia julibrissin Durazz.

本研究论文在综述国内外对合欢属Albizzia三萜皂苷化学成分和药理作用研究进展的基础上,利用传统植化分离手段和现代分离技术,包括大孔树脂、硅胶、葡聚糖凝胶、反相硅胶等柱色谱,制备高效液相色谱法等技术从中药合欢皮中分离得到了4个化合物,其中,2个新化合物和2个己知化合物,并进一步通过现代分析技术IR,ESI-MS,~1H-NMR,~(13C-NMR,HMBC,HMQC,~1H-~1HCOSY等和化学方法鉴定了2个新化合物的结构分别是:3-O-[β-D-吡喃木糖基(1→2)-β-D-吡喃夫糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖基]-21-O-[(6S)-2-反式-2,6-二甲基-6-O-β-D-吡喃鸡纳糖基-2,7-辛二烯酸基]-金合欢酸-28-O-α-L-呋喃阿拉伯糖基(1→4)[β-D-吡喃葡萄糖基(1→3)]-α-L-吡喃鼠李糖基(1→2)-β-D-吡喃葡萄糖苷,金合欢酸3-O-β-D-吡喃葡萄糖基(1→3)-β-D-吡喃夫糖基(1→6)[β-D-吡喃木糖基(1→2)]-β-D-吡喃葡萄糖苷;2个已知化合物结构分别是:金和欢酸内酯3-O-β-D-吡喃木糖基(1→2)-β-D-吡喃夫糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖苷,金和欢酸内酯3-O-β-D-吡喃木糖基(1→2)-α-L-吡喃阿拉伯糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖苷。

Therefore,the xylem parts should be used as raw material to extract the total saponins.

因此,在提取远志中的总皂苷时,应选用根皮为原料药材。

Sixteen compounds were separated from 80% ethanol extract of Plant A, they were:-lariciresinol,-isolariciresinol,-isolariciresinol 9-O-β-D-glucopyranoside, tanegoside B, apiginin, apigenin 7-O-β-D-glucoside, apigenin 7-O-β-neospheroside, quercetin 3-O-β-D-glucopyranoside, 1, 7-dihydroxy-3, 4-dimethoxyxanthone, 3-O- [α-L-rhamnopyranosyl (1-4 ] -β-D-glucopyranoside-(25S)-5β-spirostan-3β-ol , 3β-O-D-glucopyranoside quinovic acid, mangiferin , 3'-p-hydroxybenzoyl-mangiferin, physcion, benzenyl methanol β-D-glucopyranoside and Vanillic acid.

结果: 1。从植物A的80%乙醇提取物中共分离得到16个化合物,分别为:-落叶松脂醇、-异落叶松脂醇、异落叶松脂醇9-O-β-D-吡喃葡萄糖苷、tanegoside B、芹菜素、芹菜素7-O-β-葡萄糖苷、芹菜素7-O-β-新橙皮糖苷、槲皮素3-O-β-D-吡喃葡萄糖苷、1,7-二羟基-3,4-二甲氧基-口山酮、菝葜皂苷元-3-O-[α-L-吡喃鼠李糖基(1-4)]-β-D-吡喃葡萄糖苷、喹诺酸3β-O-D-葡萄糖苷、知母宁、3′-对羟基苯甲酸-知母宁、大黄素甲醚、苯甲醇-β-D-吡喃葡萄糖苷、香草酸。

Results: The expression of CTGF protein and CTGF mRNA in the nomal and sham operation group is low in the intracytoplasm of Mesangial cells, renaltubular epithelial cells and renal interstitial cells. Compare with sham operation group, the expression of CTGF protein and CTGF mRNA as yellow particulate in the mode group was markedly increased, and the fibrosis of nephridial tissue is obvious. Panaxnotoginseng could significantly decrease the expression of CTGF protein and CTGF mRNA(P.05), and there was no significant difference between Panaxnotoginseng treatment group and Benazepril treatment group.

结果:正常组及假手术组肾小球系膜细胞、肾小管上皮细胞以及肾间质细胞胞浆内有少量CTGF蛋白及其mRNA的黄色颗粒状阳性反应物,模型组上述部位的CTGF蛋白及其mRNA呈强阳性表达,三七总皂苷组上述指标表达较模型组显著减少,有统计学差异(P.05),与阳性药物组比较差异不显著。

"My dermatitis and daughters eczema are better since started using the soap"- K Nash, Taupo

自从开始用你们家的皂后,我的皮炎,我女儿的湿疹,都好了很多。K Nash,陶波

Cleaning Equipment Series: floor cleaning machine; polishing machine; Stone refurbished machine; vacuum suction machine; portable polishing machine; three-speed fan; clean cars; room service vehicles; pressing water; Hand Dryer; cleaning supplies Series: Titanium, stainless steel cup smoke; mats; elevator pad; mop; dust pushed; Blade; push of water; Tu traps; glass blowing; telescopic rod; notice boards; safety rope; belts; hanging plate; self-locking device; large Volume carton; towel carton; automatic fragrance machine; soap dispenser; watering can; sprayer; mobile cleaning basket; scouring pad; plastic mats, wear-resistant floor mats, anti-skid mats, composite mats, spinning and mats, floor mats Polaroid United States, Qualcomm mats cleaning agent at the end of series: air fresheners;§à; hand sanitizer; disinfectants; surface wax; at the end of wax; maintenance wax; furniture wax; wood floor wax; free throw wax ; from wax water; low foam carpet water; carpet stains in addition to agent; of foam agent; electrostatic dust lead agent; Degreaser; derusting agent; In addition to gel; wall cleaning agent; acidic, alkaline cleaning agents; washed stone water; bathroom cleaners; cement ash agent;àagent; aromatic ball; Bi Livzon; hundred Livzon; rub silver paste; rubbed copper water; stainless steel brightener; aluminum brightener; crystal hard powder; K2, K3 powder; Stone derusting agent; stone care agent; clean and bright daily sundry goods series: indoor and outdoor environmental dustbin; the garbage bin; debris barrels; buckets; radius wastepaper basket; trash bag; folding ladder; Human word ladder; Block 1 meter Benchmarking; peracetic acid; 84 fluid; alcohol; Laisu water; hydrochloride; distempers Mastics thinner; cleaning Ling; detergent; floor brush; Dunbur;ó; broom; dustpan;§°brush; Paper Chuai son; push snow shovel; towel; toilet paper; gloves; scouring pad; sandalwood; clean ball; wire cotton; labor supplies; cleaning service

钛金、不锈钢烟盅;地垫;电梯垫;地拖;尘推;铲刀;推水器;涂水器;玻璃刮;伸缩杆;告示牌;安全绳;安全带;吊板;自锁器;大卷纸盒;擦手纸盒;自动飘香机;皂液器;喷壶;喷雾器;手提清洁篮;百洁垫;塑胶地垫、耐磨地垫,防滑地垫,复合地垫,喷丝地垫,宝丽美地垫,通底地垫空气清新剂;玻璃清洁剂;洗手液;消毒剂;面蜡;底蜡;保养蜡;家私蜡;木地板蜡;免抛蜡;起蜡水;高低泡地毯水;地毯除渍剂;化泡剂;静电牵尘剂;除油剂;除锈剂;除胶剂;外墙清洁剂;酸性、碱性清洁剂;洗石水;浴室清洁剂;水泥除灰剂;洁厕剂;芳香球;碧丽珠;百丽珠;擦银膏;擦铜水;不锈钢光亮剂;铝品光亮剂;晶硬粉;K2、K3粉;石材除锈剂;石材护理剂;洁而亮室内、外环保垃圾桶;果皮箱;杂物桶;水桶;方圆纸篓;垃圾袋;折叠梯;人字梯;1米线标杆座;过氧乙酸;84液;酒精;来苏水;盐酸;硝基漆稀料;洗洁灵;洗衣粉;地板刷;墩布;笤帚;扫帚;簸箕;恭桶刷;皮揣子;推雪铲;毛巾;卫生纸;手套;百洁布;檀香;清洁球;钢丝棉;劳保用品;保洁服

This is because milk contains more calcium and dairy protein, sugar and starch contains relatively reduced; easy to form after ingestion of calcium soap cause constipation; life without the law, the baby did not train on time and bowel habits, but also easily lead to constipation; some chronic diseases such as rickets, Dermatomyositis also easily leads to malnutrition, such as infants and children caused by constipation, young parents must pay more attention to early prevention.

这是因为牛奶中含有更多的钙和酪蛋白,糖和淀粉含有量相对减少;食入后容易形成钙皂引起便秘;生活没有规律,对婴儿没有训练成按时排便的习惯,也容易引起便秘;有些慢性疾病如佝偻病、皮肌炎等导致营养不良也易引起婴幼儿便秘,年轻的父母必须对此多加注意,及早预防。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。