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In hematopoietic stem cell transplantation, different originated and differentiated DCs can be modulated to prevent and cure GVHD, and to promote engraftment of hematopoietic stem cells.

但是在发挥移植物抗白血病作用的同时常常会导致严重的移植物抗宿主病,GVHD是Allo-HSCT最常见的并发症,严重的GVHD也是影响移植成功的关键。

I never imagine my family past away. Because it was so unreal. Although dad always have little health problems, he was still a man with a strong willpower. On the last days of him, he never gave up even with fever, puked and headache. I thought he could still alive for the next 8-10 years even he had leucocythemia. Even mum called us that dad is gone. I still didn't believe. Until I can touch his cold hand, I finally sure this time, dad didn't make it.

我从未想过家人的逝去,就以前来说那太不现实,尽管爸一直小病不断,但是他是一个意志力非常强大的人,在他最后的那段日子里,呕吐、头痛、高烧,满身的针孔,他从来没有放弃过,所以尽管他得了白血病,压根儿我还觉得爸能够活多至少8-10年,即使妈打电话给我们说爸走了,我仍然不相信,直到我摸到了爸逝去后冰冷的手脚,我才确定,这次,爸真的没有挺过去。

The plant Quarantine Lab had intercepted more than 200 quarantine pests such as : Tilletia indica , Tilletia controversa , Bursaphelenchus xylophilus , sorghum halepense , Acanthoscelides obtectus , Sternochetes mangiferae , Bactrocera dorsalis , Coptoermes curvignathus for nearly 5000 batches ; The Animal Quanantine Lab had intercepted about 20 cow which had some pathogens evidence of infectious disease such as : bovine infectiouse rhinotracheitis , leukaemia bovum , paratuberculosis and so on ; The food microorganism lab had detected over 300 unqualified products such as Salm-Sury , Listeria monocytogenes , Mycobacterium paratuberculosis etc .

多年来,分中心各实验室切实履行严格把关的职责,植物检疫共截获大豆疫霉病菌、小麦印度腥黑穗病菌、小麦矮腥黑穗病菌、松材线虫、假高梁、菜豆象、芒果果核象甲、桔小实蝇、大家白蚁等国家禁止进境的危险性有害生物220 多种近10000 批次;动物检疫发现感染牛传染性鼻气管炎、牛白血病、副结核等传染病的疫牛20 多头;食品微生物检测共检测沙门、单增、副结核的不合格商品300 多批;分子生物学实验室为国内企业出具非转基因证书和不含有牛羊源成分证书50 余份,使相关的产品能够顺利出口到欧盟、韩国和日本等国。

There is no mature scheme on haploidentical non-T-depleted transplantation in China. Prognosis of chemotherapy is poor for refractory and high-risk leukemia. Allogene hematopoietic stem cell transplantation should be applied without delay. If we can go beyond the histocompatibility leukocyte antigen boundary, HLA-haploidentical family members would became the resource of allo-HSCT donors.

目前,国内外尚无单倍型相合未去T细胞移植成熟的方案,对于难治和高危白血病患者,化疗预后是很差的,应不失时机进行异基因造血干细胞移植,如果能够跨越人类主要组织相容性抗原的限制,用人类主要组织相容性抗原半相合的亲属作为造血干细胞移植的供体,就可以彻底解决干细胞来源问题。

Preliminary antitumor activity in vitro of the new compounds indicated that the compounds have obvious inhibitory effect on human leukaemia cell (HL-60) and human galactophore cancer cell (MDA-MB-468) in the concentration of 10-4 mol/L. This result is a basis for further study on the synthesis and biological activity of this kind of compounds.

对所合成的10个新化合物进行了抗肿瘤体外生物活性试验,初步生物活性实验结果表明,该类化合物在浓度为10-4 mol/L时对人白血病细胞株(HL-60)和人乳腺癌细胞株(MDA-MB-468)有明显的抑制作用,在浓度为10-5 mol/L时没有明显的抑制作用,这一研究结果为进一步研究此类化合物的合成、生物活性的研究奠定了基础。

At the fifth passage, two cell strains were made into cell suspension at l×10^9L^(-1). 0.5 mL was subcutaneously incubated at the inguina of each rat for 8 weeks. Amplified cells were cultured in PGC culture medium and non-adherence culture flask till idiosome formed, adhered and differeotiated.

体内实验取连续传5代的2个细胞株,分别制备浓度为l×10^9L^(-1)的细胞悬液,于每只小鼠两侧腹股沟处皮下各接种0.5 mL,培养8周体外分化采用无私附特性的培养瓶和除去白血病抑制因子的原始生殖细胞培养液,以脱饲养层法悬浮培养扩增的细胞,直到拟胚体形成及贴壁分化。

It was indi-cated that compound Ⅳ and Ⅴ possess antitumor activity. The〓 of 〓 and 〓 was 7.85 and 7.45 μg/mL respectively to〓 compound Ⅳ,Ⅴ and Ⅶ show pesticidal activity. The inhibi-tory effect of compound Ⅶ(2) was 1OO% to Barnyardgrass,and 100% to Rice Sheath Blight.

表明化合物Ⅳ、Ⅴ具有一定的抗癌活性(如Ⅳ(1)及Ⅴ(2),对人白血病细胞株〓的〓分别为7.85和7.45ug/ml,化合物Ⅳ、Ⅴ及Ⅷ具有一定的农药活性(如Ⅷ(2)在50ppm时对水稻纹枯菌的抑制率为100%,对稗草的抑制率(100ppm为100%。

VDAC2 and aldolase A identified as membrane proteins of K562 cells with increased expression under iron deprivation Abstract: We have shown previously that iron deprivation significantly stimulates the uptake of non-transferrin ferric iron from ferric citrate by erythroleukemia K562 cells and that this stimulation depends on protein synthesis.

VDAC2和醛甲确定膜蛋白的K562 细胞表达增加下铁剥夺摘要:我们已经表明以前铁剥夺大大刺激了摄取的非转铁铁铁柠檬酸的白血病K562细胞细胞和刺激,这取决于蛋白质的合成。

Some patients with childhood B-ALL had high expression of cyclin D3, But MRD could not be detected by cyclin D3 because the bone marrows of childhood acute myeloid leukemia in remission had high expression of cyclin D3 after chemotherapy.

部分B-ALL患者有较强的cyclinD3表达,但由于化疗后增生的CD19细胞亦有cyclinD3的高表达,所以难以使用cyclinD3作为特异性的白血病相关抗原检测MRD。

However, on 4th March 2009, her life took a fatal turn. She was diagnosed with Acute Lymphoblastic Leukemia, a life-threatening disease that will post a staggering SGD 400,000 medical bill to her middle-income family (Xiaoou's mother is unemployed. Her father is a normal worker with average income of SGD 400 per month).

就在这梦想愈发清晰的边缘,一切都在一纸急性淋巴性白血病确诊通知书前面,瞬间崩塌了。40万新币的医药费对于她工薪阶层的家庭来说,是个天文数字(她妈妈下岗多年,爸爸是月收入约2000元人民币的普通职工)。

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但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。