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THis conjugate method is effective and common for conjugating HHT with the other McAbs of anti-Leukemia.

表明此种交联方法用于制备抗其它类型白血病抗体与高三尖杉酯碱导向药物也是行之有效的,因而具有较普遍的应用意义。

Importantly, YM529 prolonged the survival of NOD/SCID mice engrafted with human primary leukemic cells.

更重要的是,YM529延长植入人类原发性白血病细胞NOD/SCID小鼠的生存时间。

Leukemia is one of the common tumors,and it seriously harms to the health.

白血病是人类最常见的恶性肿瘤之一,严重威胁人群的身心健康。

AIM: To explore whether inhibition of NF-κB by antioxidant pvrrolidine dithiocarbamate sensitizes leukemia cells to cytotoxic drugs and its mechanism.

目的:探讨化疗诱导性核因子κB的活化机制及抗氧化抑制NF-κB活化对白血病细胞凋亡及化疗敏感性的影响。

G-CSF sensitizes leukemia cells to the effect of Ara-C and aclarubicin then enhances the response. The mechanism is that G-CSF can enhance cytotoxicity to drugs such as Ara-c and aclarubicin by promoting G0-phase cells into the reproductive cycle. Apoptosis inducing is the main way.

G-CSF可增加化疗药物对AML的疗效,其作用机制主要是通过G-CSF促使GO期白血病细胞进入细胞增殖周期,增加细胞周期特异性化疗药物的细胞毒性,诱导细胞凋亡是主要途径。

Other studies winnowed out abnormal DNA in lung adenocarcinoma tumors and acute myeloid leukemia

其他的研究筛选出了肺腺癌肿瘤和急性髓细胞性白血病中的异常DNA。

This relationship was found to be particularly strong for myeloid leukaemia, which was also observed in the study of anatomists and in several of the studies of embalmers.

这种关系被认为是极强的骨髓白血病,这也是观察和解剖学研究的一些研究Embalmers。

Here is another view of a peripheral blood smear in a patient with CML. Often, the numbers of basophils and eosinophils, as well as bands and more immature myeloid cells are increased.

慢性髓性白血病外周血涂片,常见较多嗜碱性粒细胞和嗜酸性粒细胞,也有较多的杆状核嗜中性粒细胞和不成熟的髓细胞。

This study was purposed to observe the changes of caspase-3 activity during apoptosis of HL-60 cells induced by an iron chelator, DFO, and to explore the mechanism underlying apoptosis in HL-60 cells.

为了研究铁螯合剂—去铁胺(deferoxamine,DFO)诱导人白血病细胞株HL-60凋亡时半胱天冬酶-3(caspase-3)活性的变化并探讨DFO诱导凋亡的可能机制。

The activity of leukemic MLL fusions is believed to be directly contributing to the conversion of normal bone marrow cells into leukemic cancer cells.

目前认为,这种融合引起MLL的激活直接促成了正常骨髓细胞向白血病癌细胞的转变。

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