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According to previous clinical experiences of the authors, plumbago zeylanica was effective against acute promyelocytic leukemia. However, its effectiveness has never been proven experimentally or unequivocally clinically.

根据作者已往的临床经验,中草药白花丹对急性早幼粒细胞白血病治疗有效,但至今尚无关于白花丹对APL疗效方面的系统研究。

Effects of Plumbagin on the Human Acute Promyelocytic Leukemia Cells In Vitro Abstract According to previous clinical experiences of the authors,plumbago zeylanica was effective against acute promyelocytic leukemia.

根据作者已往的临床经验,中草药白花丹对急性早幼粒细胞白血病治疗有效,但至今尚无关于白花丹对APL疗效方面的系统研究。

But the priapism caused by leukemia can only be relieved by chemical therapy.

白血病诱发的异常勃起应强调原发病的治疗。

A human promyelocytic leukemia cell mutant (HL-60-AR) with deficiency in HGPRT and resistance to 8-AG was established by treat〓nt of the HL-60 cells with MNNG and prescreened in 0.3% agar RPMI-1640 semisolid medium containing 8-AG. The mutant cells show the following characteristics:(1) resistant to cytotoxic action of 8-AG and growing vigorously in medium containing 20ug/ml 8-AG;(2) capable of forming 〓〓 colonies in soft agar medium in the presenee of 8-AG:(3) highly sensitive to HAT selective medium and fail to growing in HAT medium of form colonies in soft agar medium containing HAT;(4) completely deficinet in HGPRT activity; and (5) no radioactive silver grains over the mutant cells due to the absence of -hypoxanthine incorporation showed by radioautography.

一、用MNNG诱变和8-AG进行抗性筛选,成功地建立了一株抗高浓度8-AG和完全缺失HGPRT活性的人早幼粒白血病细胞突变株(HL-60-AR),该细胞能抵抗8-AG的毒性作用,对HAT选择培养基十分敏感,检测不到HGHRT活性,不能参入〓H一次黄嘌呤。

Objectives To investigate ras gene expression in childhood acute leukemia and its significance in the treatment and prognosis assessment.

目的 ras基因在儿童急性白血病中的表达及其与治疗和预后的相关性分析。

The detection of MLL gene rearrangement is of great importance in predicting prognosis and guiding therapy in AL.

MLL基因重排的检测对急性白血病预后判断和治疗方案的选择具有重要意义。

Objective To study the mechanism of drug resistance of APL to ATRA and the methods of reversion.

目的 揭示急性早幼粒细胞白血病产生维甲酸耐药的机制,探讨耐药性逆转的方法。

In addition, children with acute lymphoblastic leukemia and rhabdomyosarcoma hae been shown to hae "a significant increased frequency of birthmarks."

此外,患有急性淋巴细胞性白血病和横纹肌肉瘤的儿童出现胎记的几率显著增加。

HSCT becomes one of the standard therapies for sele...

全球接受移植的病人明显增加,已成为治愈白血病、淋巴瘤、多发性骨髓瘤等血液系统疾病的重要方法之一。

The 1st annual CML sponsored EMMA indoor meeting was held last weekend at the Newark Showground, where the organising club had built a challenging and exciting track that ensured a lot of action and close racing.

第一年度慢性粒细胞白血病赞助艾玛室内举行了一次会议上周末在纽瓦克展,其中组委会俱乐部建立了一个具有挑战性和令人兴奋的轨道,确保了很多行动和密切的比赛。

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