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To explore the mechanism of berbamine inducing apoptosis in human leukemia Jurkat cells.

研究小檗胺诱导人白血病Jurkat细胞凋亡的机制。

[Purpose] To explore the mechanism of berbamine inducing apoptosis in human leukemia Jurkat cells.

导读:[目的]研究小檗胺诱导人白血病Jurkat细胞凋亡的机制。

Objective To study the relation between Alcian blue-stained faggot Auer body and the genetic abnormality of acute promyelocytic leukemia.

目的 研究阿利新蓝染色检测柴捆状Auer小体与急性早幼粒细胞白血病遗传学标志的相关性。

AIM: To investigate the effects of T cell activators on the mRNA expression of recombinationactivating genes in Jurkat cells.

目的:研究T细胞激活剂PHA,抗CD3 mAb, PMA+A23187对人T细胞白血病细胞株Jurkat重组激活基因mRNA表达水平的影响。

ObjectiveTo investigate the effect of curcumin on the sensitivity of human leukemia cell line HL-60 to adriamycin.

目的研究姜黄素是否增强人白血病细胞株HL60对阿霉素的敏感性及其作用机制。

Influence of "Bu-sheng-yi-qi" granule to natural killer cell and activity of interleukin-2 of P388 leukemia mice after treating by chemistry therapy.

补肾益气冲剂对P388白血病小鼠化疗后自然杀伤细胞、白介素-2活性的影响。

Methods Hepatic cells were obtained from fetal rats by means of mechanical separation and hanging-drop culture, and after two days of primary culture, the medium was changed for further cell culture in the presence of 20% fetal bovine serum (containing glucose 25ml/L, mycillin 100 U/ml, pH 7.6), 10 mmol/L nicotinamide, 1 mg/L insulin, affix N2, basic fibroblast growth factor, stem cell factor, epidermal growth factor and leukemia inhibitory factor.

采用机械分离法结合悬滴培养法获得胎肝干细胞,原代培养2d后改变培养基,添加含20%胎牛血清的DMEM(含25ml/L葡萄糖,100U/ml青链霉素,pH值7.6),添加烟酰胺10mmol/L,胰岛素1mg/L,N2添加剂,碱性成纤维细胞生长因子、表皮生长因子、干细胞因子、白血病抑制因子各20μg/L诱导分化为nestin阳性细胞。

Methods Tumor-bearing mouse models were set up by transplanting hepatoma (H22), sarcoma S180 and leukemia (L1210). Tumor inhibitory action and life-prolonging effect of AIDI on the mice, as well as its synergism with CTX were observed.

抗肿瘤体内实验:建立小鼠移植性肉瘤S180和小鼠肝癌H22的实体瘤模型,艾迪粉针剂对小鼠尾静脉给药,连续处理7d,第8天剥离瘤块称质量,计算抑瘤率,与化疗药合并用药考察减毒增效作用;建立小鼠L1210白血病模型,阳性对照组为顺铂,考察生命延长率。

This results in the induction of a broad range of leukemias and lymphomas.

这引起广泛白血病和淋巴瘤的诱导发生。

Flow cytometry was used to detect the expression of pRb in 89 cases of acute leukemia (including 25 AML, 10 T-ALL and 54 B-ALL) and bone marrows from 7 normal children. Meanwhile the cell cycle in some cases was analyzed .

对89例初发小儿急性白血病患者(包括25例AML, 10例T-ALL, 54例B-ALL)及7例正常对照骨髓标本,采用流式细胞术分别检测治疗前后视网膜母细胞瘤蛋白的表达情况,并对部分病例进行细胞周期分析。

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