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FINDINGS: Somatically acquired JAK2 mutations were identified in 16 (18%) patients with Down's syndrome-associated acute lymphoblastic leukaemia.

结果:唐氏综合征相关的急性淋巴母细胞白血病患者中有16例(18%)鉴定出了获得性体细胞JAK2突变。

In conclusion , ERK and telomerase serve a function to some extent in drug resistance of leukemia and ovariancarcinoma cells. The inhibition of ERK signal transduction pathways led to reduction of phosphorylated ERK1 and ERK2protein expression level , and successionally down2regulated the telomerase activity.

通过阻抑ERK通路,降低磷酸化ERK1/ 2蛋白表达水平,进而下调端粒酶活性,可以达到增强白血病和卵巢癌耐药细胞对HRT 或DDP 敏感性的目的。

The effects on cell viability of the exogenous gene products were observed by trypan blue dye exclusion test.

以探讨hc56、hc71和hc90基因产物的生物学功能,及其与白血病/淋巴瘤发病关系。

Aven mRNA expression is abnormal in childhood ALL and is associated withthe clinical classification of childhood ALL.

结论Aven在儿童急性淋巴细胞性白血病中异常表达,且为不良的独立预后因素。

Methods RT-PCR was used to detect the expression of Aven mRNA in 55 cases ofchildhood ALL. The control group included 11 childhood patients with no malignanthematological diseases.

方法应用RT-PCR检测55例儿童急性淋巴细胞性白血病患者Aven基因mRNA的表达水平,11例非恶性血液病患儿为对照组。

Purpose: To investigate the effects of Acrylamide on the HPRT gene of human promyelocytic leukemia ceils.

目的:为了研究丙烯酰胺对人白血病HL—60细胞HPRT位点的影响作用。

An cell-based ELISA for cell surface antigen using interdigitated electrode array with enzymatic silver deposition was developed.

建立了一种检测白血病细胞表面抗原的细胞酶联免疫电化学分析新方法。

Outside the cells, it moonlights as autocrine mobility factor involved in cancer metastasis, neurolukin supporting the survival of specific neurons, and maturation factor mediating the differentiation of myeloid leukemic HL-60 cells to terminal monocytic cells.

在细胞外,PGI是一种肿瘤自泌移动因子和肿瘤转移有关,也是一种神经白介素和促分化成熟介子,分别具有支持脊髓及感觉神经元存活的能力和诱导白血病细胞HL-60成为单核白血球。

AIM: To investigate whether celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, potentiates the anti-leukemia activity of STI571 in K562 cells METHODS: K562 cells were treated with STI571, celecoxib or combination of both at different concentrations in suspension culture.

目的:探讨环氧合酶-2(COX-2)抑制剂塞来昔布促进酪氨酸激酶抑制剂STI571的抗白血病效应及其机制。

The expression of c-myc gene had staistical difference between recuperates and non-recuperates (P<0.05) in 20 cases of acute myelogenous leukemia.

白血病组中,化疗后完全缓解与不缓解病人c-myc基因的表达有显著性差异(P<0.05)。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。