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During the treatment and in the followup duration, 8 eyes (8/13) had new tumors and recurrences. Finally, 2 eyes (2/13) were enucleated whil e 11 eyes (11/13) were saved in which 8 (8/11) recovered or remained good visual acuity. None of 9 patients had serious side effects of chemotherapy like leucoc ythemia, functional damage of liver and kidney, and dysacousia.

治疗期间及治疗后随访期间共有8只眼出现了肿瘤和肿瘤种植的复发和新发,经补充冷冻和TTT治疗后,最终2只眼(2/13)摘除,11只眼得以保留,其中8只眼恢复或保持较好有用视力。9例患者均未发生白血病、肝肾功能及听力损害等严重化学治疗毒性反应。

Loss-of-function mutations in telomerase complex genes can cause bone marrow failure, dyskeratosis congenita, and acquired aplastic anemia, both diseases that predispose to acute myeloid leukemia.

端粒末端转移酶的复杂基因丧失功能性突变可导致骨髓衰竭、先天性角化不良及获得性再生障碍性贫血,这些疾病都可以诱发急性髓样白血病。

To study the regulation mechanism of SOCS-3 (Suppressor of cytokines signals-3) for erythropoietic development, small interference RNA expression vectors of SOCS-3 were constructed and transferred in to the K562 cell lines stably by lentiviral system.

为了研究细胞因子信号转导分子3(suppressor of cytokine signals-3,SOCS-3)对造血发育的影响,构建了SOCS-3慢病毒siRNA干涉载体,并转染人红白血病细胞株K562。

The overexpression of CXCR4 on AL cell may be the molecular mechanism of extramedullary infiltration in leukemia.

急性白血病细胞过量表达CXCR4,可能是其浸润髓外组织的分子机制之一。

Objective: To research the effect and mechanism of Quanxie Decoction combined with chemotherapy on acute leuckemia extramedullary infiltraiton.

目的 探讨全蝎水煎液联合化疗干预急性白血病髓外浸润的疗效及机理。

Abstract]Objective:To analyse the adverse drug reaction of high dose methotrexate in treatment of childhood acute lymphoblastic extramedullary leukemia.

目的:分析比较进口与国产甲氨蝶呤在预防治疗儿童急性淋巴细胞髓外白血病过程中不良反应的发生率。

The effects of gambogic acid on the growth of three leukemia cell lines were studied by MTT assay.

结果:(1)藤黄酸对HL-60、U937、K562三种白血病细胞系均具有明显的抑制增殖作用。

Methods In vitro CFU-GM culturing was used to study the effect of adult serum and CB serum on hemapoietic progenitor cells of normal bone mar row and children with AL in period of PCBS.

采用体外粒单细胞集落形成单位培养法,观察正常成人血清和脐血清,对正常造血细胞和急性白血病化疗后抑制期骨髓造血细胞增殖的影响。

Objective Chronic myeloid leukemia, with of chromosome, is one of primary clonal malignancies of hemapoietic stem cell. Philadelphia chromosome is the hallmark of malignancies clone in CML.

研究背景与目的:慢性髓系白血病是一种原发于多能造血干细胞的恶性克隆性疾病,第9号与第22号染色体相互易位形成Ph染色体是其肿瘤恶性克隆性标志。

So there was a wide application perspective for TPL in treatment of hematological tumors.

早在上世纪70年代,Kupchan等[1]就发现TPL具有显著的抗白血病作用。

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By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候,里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色,卵在发育96h后卵基本全部孵化。

There was a conflict between plebs and patricians in ancient Rome in 494BC.

在公元前494年,罗马发生了一次平民反对贵族的斗争。