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Results] Berbamine could significantly inhibit the proliferation of Jurkat cells in a dose-dependent manner and the IC50 value was 6.6±0.5μg/ml at 48 hours. Berbamine also selectively induced apoptosis of Jurkat cells which were arrested in the S phase. In addition, expression of caspase-3 protein of Jurkat cells increased after exposure to berbamine.

结果] 小檗胺能选择性抑制人白血病Jurkat细胞生长且呈浓度依赖关系,作用48h Jurkat细胞IC50值为6.6±0.5μg/ml;小檗胺能诱导Jurkat细胞凋亡,使细胞周期阻滞于S期;同时细胞caspase-3蛋白表达增高。

Results Berbamine could significantly inhibit the proliferation of Jurkat cells in a dose-dependent manner and the ICso value was 6.6±0.5μg/ml at 48 hours. Berbamine also selectively induced apoptosis of Jurkat cells which were arrested in the S phase. In addition, expression of caspase-3 protein of Jurkat cells increased after exposure to berbamine.

结果小檗胺能选择性抑制人白血病Jurkat细胞生长且呈浓度依赖关系,作用48hJurkat细胞IC50值为6.6±0.5μg/ml;小檗胺能诱导Jurkat细胞凋亡,使细胞周期阻滞于S期;同时细胞caspase-3蛋白表达增高。

Objective To study the relation between Alcian blue-stained faggot Auer body and the genetic abnormality of acute promyelocytic leukemia.

目的 研究阿利新蓝染色检测柴捆状Auer小体与急性早幼粒细胞白血病遗传学标志的相关性。

AIM: To investigate the effects of T cell activators on the mRNA expression of recombinationactivating genes in Jurkat cells.

目的:研究T细胞激活剂PHA,抗CD3 mAb, PMA+A23187对人T细胞白血病细胞株Jurkat重组激活基因mRNA表达水平的影响。

ObjectiveTo investigate the effect of curcumin on the sensitivity of human leukemia cell line HL-60 to adriamycin.

目的研究姜黄素是否增强人白血病细胞株HL60对阿霉素的敏感性及其作用机制。

ObjectiveTo investigate the effect of curcumin on the sensitivity of human leukemia cell line HL-60 to adriamycin.

目的研究姜黄素是否增强人白血病细胞株HL??

This relationship was found to be particularly strong for myeloid leukaemia, which was also observed in the study of anatomists and in several of the studies of embalmers.

这种关系被认为是极强的骨髓白血病,这也是观察和解剖学研究的一些研究Embalmers。

A new study links small doses of the popular artificial sweetener aspartame to leukemia, lymphoma and breast cancer in rats.

一项新的研究表明小剂量的受欢迎的人工甜味剂阿巴斯甜和老鼠的白血病,淋巴瘤和乳腺癌相关。

Here is another view of a peripheral blood smear in a patient with CML. Often, the numbers of basophils and eosinophils, as well as bands and more immature myeloid cells are increased.

慢性髓性白血病外周血涂片,常见较多嗜碱性粒细胞和嗜酸性粒细胞,也有较多的杆状核嗜中性粒细胞和不成熟的髓细胞。

This study was purposed to observe the changes of caspase-3 activity during apoptosis of HL-60 cells induced by an iron chelator, DFO, and to explore the mechanism underlying apoptosis in HL-60 cells.

为了研究铁螯合剂—去铁胺(deferoxamine,DFO)诱导人白血病细胞株HL-60凋亡时半胱天冬酶-3(caspase-3)活性的变化并探讨DFO诱导凋亡的可能机制。

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