白血病

To elucidate the possible mechanism of differentiation and/or apoptosis in NB4, K562 cells induced by tributyrin, a histone deacetylase inhibitor , the level of acetylated histone H3 was detected by Western blot, p21(superscript WAF1) expression was detected by semi-quantitative RT-PCR.

为了探讨组蛋白去乙酰化酶抑制剂三丁酸甘油酯(tributyrin， TB)诱导NB4、K562白血病细胞分化和凋亡的作用机制，利用Western blot方法及逆转录聚合酶链反应检测TB作用前后NB4、K562细胞组蛋白H3乙酰化水平以及p21(上标 WAF1)表达量的改变。

The effects on cell viability of the exogenous gene products were observed by trypan blue dye exclusion test.

以探讨hc56、hc71和hc90基因产物的生物学功能，及其与白血病/淋巴瘤发病关系。

Objective To explore the feasibility of human leucocyte antigen haploidentical related T-cell undepleted allogeneic bone marrow transplantation combined with Chinese medicine for the treatment of leukaemia.

目的探索半相合未去除T细胞骨髓移植联合中药治疗白血病的可行性。

The treatment of leukemic cell with a longterm, intermittent,singular, unefficient chemotherapeutic agents could induce multi-drug resistant cells. Interleukin-4 can reverse the multi-drug resistance by inhibiting the expression of p-gp and increasing the quantity of intracellular chemotherapeutic agents in tumor cells. The effects were probably related to the inhibition of the PKC activity.

长期、间断、单一、不足量的化疗可导致 MDR；IL-4 可通过抑制肿瘤细胞的 p-gp表达，增加化疗药物在肿瘤细胞内的聚集而逆转白血病细胞的MDR，此作用可能与抑制 PKC的活性有关。

Aven mRNA expression is abnormal in childhood ALL and is associated withthe clinical classification of childhood ALL.

结论Aven在儿童急性淋巴细胞性白血病中异常表达，且为不良的独立预后因素。

Methods RT-PCR was used to detect the expression of Aven mRNA in 55 cases ofchildhood ALL. The control group included 11 childhood patients with no malignanthematological diseases.

方法应用RT-PCR检测55例儿童急性淋巴细胞性白血病患者Aven基因mRNA的表达水平，11例非恶性血液病患儿为对照组。

Moreover leukaemia can be a reaction to a fungine mass, whose localisation is unknown.

此外白血病可以是反应fungine质量，其本地化不明。

Sometimes radiation therapy may be used to treat a large mass of leukemia cells in the spine or brain.

有时在椎管内或脑内存在大量白血病细胞是可以用放射治疗。

Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates［J］.

表2 26例成人白血病患者肿瘤和正常细胞线粒体DNA突变情况

Purpose: To investigate the effects of Acrylamide on the HPRT gene of human promyelocytic leukemia ceils.

目的：为了研究丙烯酰胺对人白血病HL—60细胞HPRT位点的影响作用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。