白血病

To elucidate the possible mechanism of differentiation and/or apoptosis in NB4, K562 cells induced by tributyrin, a histone deacetylase inhibitor , the level of acetylated histone H3 was detected by Western blot, p21(superscript WAF1) expression was detected by semi-quantitative RT-PCR.

为了探讨组蛋白去乙酰化酶抑制剂三丁酸甘油酯(tributyrin， TB)诱导NB4、K562白血病细胞分化和凋亡的作用机制，利用Western blot方法及逆转录聚合酶链反应检测TB作用前后NB4、K562细胞组蛋白H3乙酰化水平以及p21(上标 WAF1)表达量的改变。

The effects on cell viability of the exogenous gene products were observed by trypan blue dye exclusion test.

以探讨hc56、hc71和hc90基因产物的生物学功能，及其与白血病/淋巴瘤发病关系。

Objective To explore the feasibility of human leucocyte antigen haploidentical related T-cell undepleted allogeneic bone marrow transplantation combined with Chinese medicine for the treatment of leukaemia.

目的探索半相合未去除T细胞骨髓移植联合中药治疗白血病的可行性。

The treatment of leukemic cell with a longterm, intermittent,singular, unefficient chemotherapeutic agents could induce multi-drug resistant cells. Interleukin-4 can reverse the multi-drug resistance by inhibiting the expression of p-gp and increasing the quantity of intracellular chemotherapeutic agents in tumor cells. The effects were probably related to the inhibition of the PKC activity.

长期、间断、单一、不足量的化疗可导致 MDR；IL-4 可通过抑制肿瘤细胞的 p-gp表达，增加化疗药物在肿瘤细胞内的聚集而逆转白血病细胞的MDR，此作用可能与抑制 PKC的活性有关。

Aven mRNA expression is abnormal in childhood ALL and is associated withthe clinical classification of childhood ALL.

结论Aven在儿童急性淋巴细胞性白血病中异常表达，且为不良的独立预后因素。

Methods RT-PCR was used to detect the expression of Aven mRNA in 55 cases ofchildhood ALL. The control group included 11 childhood patients with no malignanthematological diseases.

方法应用RT-PCR检测55例儿童急性淋巴细胞性白血病患者Aven基因mRNA的表达水平，11例非恶性血液病患儿为对照组。

Moreover leukaemia can be a reaction to a fungine mass, whose localisation is unknown.

此外白血病可以是反应fungine质量，其本地化不明。

Sometimes radiation therapy may be used to treat a large mass of leukemia cells in the spine or brain.

有时在椎管内或脑内存在大量白血病细胞是可以用放射治疗。

Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates［J］.

表2 26例成人白血病患者肿瘤和正常细胞线粒体DNA突变情况

Purpose: To investigate the effects of Acrylamide on the HPRT gene of human promyelocytic leukemia ceils.

目的：为了研究丙烯酰胺对人白血病HL—60细胞HPRT位点的影响作用。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。