白血病

At present,the pathogenesy of leukemia is not very clear,which will achieve more recognition with the development of modern empirical method.

目前，白血病发病机制尚不完全清楚，随着现代实验方法的进步，人类对其发病机制有了逐渐的认识。

In chronic lymphocytic leukemia there is high frequency of loss of heterozygosity and mutation of atm gene, which related to pathopoiesis and progression of CLL.

慢性淋巴细胞白血病可出现高频率的atm基因杂合性缺失和核苷酸突变，并与其发病及侵袭性病程有关。

It was indi-cated that compound Ⅳ and Ⅴ possess antitumor activity. The〓 of 〓 and 〓 was 7.85 and 7.45 μg/mL respectively to〓 compound Ⅳ,Ⅴ and Ⅶ show pesticidal activity. The inhibi-tory effect of compound Ⅶ(2) was 1OO% to Barnyardgrass,and 100% to Rice Sheath Blight.

表明化合物Ⅳ、Ⅴ具有一定的抗癌活性（如Ⅳ(1)及Ⅴ(2)，对人白血病细胞株〓的〓分别为7.85和7.45ug／ml，化合物Ⅳ、Ⅴ及Ⅷ具有一定的农药活性（如Ⅷ(2)在50ppm时对水稻纹枯菌的抑制率为100%，对稗草的抑制率（100ppm为100%。

Thirty patients with acute promyelocytic leukemia were observed between September 1977 and October 1985. Bleeding diathesis with petechiae or ecchymosis (80%) was the most common presenting symptom. Seventeen of 24 patients with pretreated coagulation studies were diagnosed to have disseminated intravascular coagulation. Six out of 11 patients died from intracranial hemorrhage after a mean of 2.5 days of hospitalization without any treatment. DIC was responsible for death in most cases. Induction therapy with anthracycline and cytosine arabinoside combined with prophylactic heparin infusion was carried out in the remaining 19 patients. Two patients were incompletely treated. Eight out of 17 patients achieved complete remission after a mean of 63 days following chemotherapy. The remission rate was 47%.

自1977年9月至1985年10月，观察30位急性前骨髓球性白血病病帣，临床上诊断时初发症状，主要为出血现象，尤其以瘀斑出血最多，占80%。24位病人作治疗前凝血机能检查，17位出现播散性血管内凝固症候群。11位病人没有接受治疗，其中6位经诊断后平均2.5天内死於脑内出血，凝血机能检验显示5位有播散性血管内凝固症候群。19位病人接受anthracycline与ara-C并用预防性肝素静脉滴注作缓解诱导治疗，2位不完全治疗，其余17位中有8位经过平均63天之化学治疗得到完全缓解，缓解率47%。

It is relatively easy to differentiate hairy cell leukemia from marginal zone lymphoma phenotypically by flow cytometry.

通过流式细胞仪能够相对容易地将毛细胞性白血病和边缘区淋巴瘤进行鉴别。

Physalis peruviana L. is a popular folk medicine used for treating cancer, leukemia, hepatitis and other diseases.

秘鲁酸浆是一种民间广泛使用的生药，可用於治疗癌症、白血病、肝炎和其他疾病。

In peripheral blood obtained up to 77 months before a CLL diagnosis, prediagnostic B-cell clones were present in 44 of 45 patients with CLL.

45例白血病患者中，44例在CLL诊断前77个月内获得的外周血中发现了诊断前B细胞克隆。

RESULTS: On the basis of either flow-cytometric or molecular analysis, 44 of 45 patients with CLL (98%; 95% confidence interval , 88 to 100) had a prediagnostic B-cell clone; in 41 patients (91%; 95% CI, 79 to 98), the presence of the B-cell clone was confirmed by both methods. The presence of immunoglobulin heavy-chain variable genes was determined in 35 of 45 prediagnostic clones (78%).

结果：在流式细胞或分子分析的基础上， 45名白血病患者有44例（98 ％； 95 ％可信区间，88～100 ）具有诊断前B细胞克隆；在41例（ 91％； 95 ％可信区间， 79～98 ），B细胞克隆的存在得到了这两种方法的证实。45个诊断前克隆中有35个(78%)具有免疫球蛋白重链可变基因。

The condition was attributed presumptively to infection with Abelson's murine leukemia virus.

此状况推测乃由於 Abelson 小鼠白血病病毒(Abelson's murine leukemia virus)感染所致。

To prevent cross-contamination of the virus from different animals, the feed eaten by the breeding hens cannot contain animal products; they cannot test positive for Salmonella enteritidis, Salmonella pullorum or Salmonella typhi, nor for avian flu or avian leukosis viruses; and they must also be free of external hormones and antibiotics.

魏逸之称呼这些是「clean eggs」──为了避免不同动物体内的病毒交互感染，种鸡所吃的饲料不得含有动物成分；它们体内不得检出肠炎沙门氏杆菌、鸡白痢沙门氏杆菌、伤寒沙门氏杆菌，以及A型禽流感、禽白血病等病毒，也不得有贺尔蒙与抗生素的残留。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。