白血病

Background and objective Although marked progress has been made in the treatment of acute myeloid leukemia,about 20%～40% patients with AML failed to get complete remission after standard induction chemotherapy. Furthmore, approximate 70% patients in CR will die because of relapse or refractory to therapy during post remission chemotherapy.

研究背景及目的：尽管目前急性髓系白血病(acute myeloid leukemia，AML)的治疗取得了显著的进步，但仍有20％～40％的患者经标准诱导治疗未能达到完全缓解(complete remission，CR)，即使获得CR的患者，在巩固化疗后仍有70％左右复发或发展为难治性急性髓系白血病而治疗无效死亡。

Leukemia cutis seldom occurs in children, and is seen in only 6%-9% of children with leukemia.

皮肤白血病极少发生于儿童，仅占儿童白血病的6%~9%。

This may be the first case of bullous leukemia cutis and aggressive NK cell leukemia in a child, Dr. Price said.

该病例可能是首例儿童大疱性皮肤白血病合并侵袭性 NK 细胞白血病， Price 博士说。

Part two.Effect of MDM2 gene polymorphism and chemotherapy drugs in leukemia cell linesObjectives:DNR and etopside play key role in leukemia therapy.

第二部分白血病细胞系MDM2基因多态性与化疗药物的研究研究目的：DNR和VP-16在白血病治疗中发挥重要的作用。

Enzootic bovine leukemia is an infectious neoplasm caused by bovine leukemia virus. This disease is found in all countries of world which raise cows.

牛流行性白血病(Enzootic Bovine Leukosis，EBL)是由牛白血病病毒(Bovine LeukemiaVirus，BLV)所引起的一种具有传染性的肿瘤性疾病。

To date,it has been documented after transfusion of unirradiated blood components to at least 87 patients:in patients with severe combined immunodeficiency,thymic hypoplasia,and Wiskott Aldrich syndrome premature newborns and those with erythroblastosis fetalis; patients with hematologic malignancies including Hodgkin\'s and non-Hodgkin\'s lymphomas,acute myelocytic and lymphoblastic leukemias,chronic lymphocytic leukemia,and aplastic patients with solid tumors including neuroblastomas, glioblastoma,rhabdomyosarcoma,cervical carcinoma,small cell lung cancer,and germ cell tumor;patients after cardiac surgery and cholecystectomp-60;and in an apparently healthy 22-year-old woman.

目前为止，输注未辐照血液成分后，至少引起了87例TA-GVHD的发生，主要见于以下病人：严重的免疫缺陷病人、胸腺发育不全、Wiskott Aldrich综合症、早产儿、胎儿红细胞增多症、何杰金与非何杰金氏淋巴瘤等恶性血液病人、急性粒细胞性和淋巴细胞性白血病、慢性淋巴细胞性白血病、成神经细胞瘤等实体瘤病人、横纹肌赘瘤、宫劲癌、小细胞肺癌、微细胞瘤、心脏和胆囊手术病人。

The Fas ligand appears overexpression in some AML. The pathway of Fas/Fas Ligand may involve in the mechanism of immune escape in AML.

Fas配基在部分急性髓性白血病中高表达，Fas/Fas配基途径可能参与这部分急性髓性白血病的免疫逃避。

Most, however, fall somewhere in between the stalwart supporters and the

罹患过白血病、淋巴瘤或者骨髓瘤的病人都有这样的感受，白血病的治疗不仅影响到自己同至亲密友间的关系，也会影响到与其他远亲、朋友、熟知间的联系。

Objective To explore the relationship between incidence of hemorrhage in patients with leukemia and changes of the markers of coagulation, anticoagulation and fibrinolysis.

目的 观察白血病病人凝血、抗凝及纤溶指标的变化，以探讨凝血系统的变化与白血病并发出血的关系。

It was also discovered that the existence of FIP 1L 1-PDGFR a fusion gene in some chronic eosinophilic leukemia can help to predict the sensitivity of this type of leukemia to Imatinib treatment.

我们还发现融合基因FIP 1L 1-PDGFRα在某些慢性嗜酸性白血病细胞中的检测阳性可预测该类白血病对Imatinib治疗的敏感性。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。