白血病

Objective To explore the establishment of EL9611-F1 mouse erythroblastic leukemia model s and to supply the models for the study of graft versus leukemia effect in H-2 haploidentical transplantation.

接种 1 0 4～ 1 0 7个EL96 1 1细胞可建立EL96 1 1 F1小鼠红白血病模型；T细胞对EL96 1 1细胞有较强细胞毒效

Keywords thalassemia;β41/42mutation;gene therapy;acute leukemia;erythroblastic

地中海贫血；β41/42突变基因；基因疗法；急性白血病；幼红细胞

The therapeutic effect of recombinant vaccinia virus encoding human IL-2 gene(IL-2VV) on the tumor-bearing mice was investigated. The tumor-bearing mice were established by subcutaneus inoculation with 2×106 FBL-3 erythroblastic leukemia cells into C57BL/6 mice.

观察了编码人白细胞介素2(IL-2)基因的重组痘苗病毒(recombinant vaccinia virus encoding human IL-2 gene，IL-2VV)对小鼠接种FBL-3红白血病细胞诱发肿瘤的治疗作用。

Our previous researches have proved that matrine with certain concentrations may induce erythroid differentiation and apoptosis of K562 human leukemia cells and evidently influence the cell cycle and telomerase activity.

我们多年来的研究证明，苦参碱在体外可明显抑制人白血病细胞K562的增殖，诱导其向正常形态分化并显著影响细胞周期和端粒酶活性。

To study the regulation mechanism of SOCS-3 (Suppressor of cytokines signals-3) for erythropoietic development, small interference RNA expression vectors of SOCS-3 were constructed and transferred in to the K562 cell lines stably by lentiviral system.

为了研究细胞因子信号转导分子3(suppressor of cytokine signals-3，SOCS-3)对造血发育的影响，构建了SOCS-3慢病毒siRNA干涉载体，并转染人红白血病细胞株K562。

First, we observed the effects of extogenous IL-15 on Jurkat cells which express IL-15 receptors.

首先，我们观察了外源性IL-15对表达IL-15受体(IL-15R)的人类T细胞白血病细胞系Jurkat细胞的体外影响。

This study was to establish a leukemic extramedullary infiltration model for exploring the mechanism.

本文通过建立人单核细胞白血病裸鼠多器官浸润模型，为对其机制进行研究提供模型基础。

The overexpression of CXCR4 on AL cell may be the molecular mechanism of extramedullary infiltration in leukemia.

急性白血病细胞过量表达CXCR4，可能是其浸润髓外组织的分子机制之一。

Objective: To research the effect and mechanism of Quanxie Decoction combined with chemotherapy on acute leuckemia extramedullary infiltraiton.

目的 探讨全蝎水煎液联合化疗干预急性白血病髓外浸润的疗效及机理。

Abstract］Objective:To analyse the adverse drug reaction of high dose methotrexate in treatment of childhood acute lymphoblastic extramedullary leukemia.

目的：分析比较进口与国产甲氨蝶呤在预防治疗儿童急性淋巴细胞髓外白血病过程中不良反应的发生率。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。