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白血病

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Methods Conventional cytogenetic analysis of R band was used to detect the abnormalities of chromosome 7 in 410 acute leukemia patients.

方法采用R带常规显带技术进行染色体检查,对410例急性白血病患者的核型进行分析。

In conclusion, cytogenetical detection is very important in differential diagnosis of clonal eosinophilic disorders and chronic eosinophilic leukemia, which is suggested to be done routinely in clinic.

在嗜酸性粒细胞增多症的诊断中,染色体的检测是判定克隆性和诊断慢性嗜酸性粒细胞白血病的重要手段,应作为常规的检测。

Myelodysplastic syndromes ; Leukemia ; myeloid ; subacute ; Cytogenetical

骨髓增生异常综合征;白血病;髓性;亚急性;细胞遗传学

DESIGN AND METHODS: To clarify the clinicopathological characteristics of this malignancy, we analyzed 27 cases of cytogenetically proven dual-hit lymphoma/leukemia.

设计和方法:为了弄清楚这种恶性肿瘤的临床病理特征,我们分析了27例细胞遗传学证明有双重打击的淋巴瘤/白血病

However, alkylating agents, such as cyclophosphamide, and the topoisomerase II inhibitors, doxorubicin and epirubicin, are associated with two types of cytogenetically distinct leukemias after adjuvant chemotherapy.

然而,烷化剂如环磷酰胺、拓扑异构酶II抑制剂、阿霉素、表阿霉素都与辅助化疗后的两种细胞遗传学不同的白血病的发生相关。

Methods Immune phenotypes were assayed in 53 patients with acute Leukemia by flow cytometer.

采用流式细胞仪对53例初治急性白血病进行免疫表型分析。

The study was aimed to investigate the mechanism of cytotoxic effect of trichosanthin on leukemia or lymphoma cell lines.

本研究的目的是探讨天花粉蛋白对人白血病和淋巴瘤细胞系的杀伤作用机制。

Clearly, new modes of therapy are necessary. The crux is to increase the specificity of cytotoxic drugs.

因此在不降低药效的情况下尽量减少化疗药物的剂量、提高抗白血病药物的选择性就成了问题的关键。

Objective To verify the influence of cytotoxic chemotherapy to in situ apoptosis in acute leukemia.

目的观察细胞毒化疗对急性白血病原位细胞凋亡的影响。

METHODS: We searched for abnormalities of the proapoptotic Bcl-x deamidation pathway in primary cells from patients with chronic myeloid leukemia or polycythemia vera, myeloproliferative disorders associated with the BCR-ABL fusion kinase and the Janus tyrosine kinase 2 (JAK2) V617F mutation, respectively.

我们分别对来自慢性粒细胞白血病或真性红细胞增多症、骨髓增生性疾病相关的BCR-ABL融合蛋白激酶及Janus酪氨酸激酶2 (JAK2) V617F突变体患者原代细胞凋亡前Bcl-x脱酰胺途径的异常情况进行研究。

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