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Proceedings of 2nd International Symposium on Autografting for chronic myeloid leukemia.

bcr-abl反义核苷酸、白介素-2体外净化慢性粒细胞白血病骨髓的效果。

OBJECTIVE: To evaluate effect of autologous hematopoietic stem cell transplantation on the treatment of acute AML.

目的:评价自体造血干细胞移植对急性髓系白血病的改善效果。

The laboratory findings of a typical CCML patient comprised of peripheral blood leukocytosis, basophilia and eosinophilia,myeloid differentiation in different stages, and increased megakaryocytes. The immunohistochemical features of the CCML consisted of highly positive MPO and CD68, significant lowering of neutrophil alkaline phosphatase, positive for Philadel- phia chromosome or chimeric BCR/ABL gene, etc. But in most cases of juvenile CCML, the Philadelphia chromosome could not be detected.

临床表现以乏力、低热、贫血、肝脾及淋巴结肿大为主要特点;典型儿童慢性髓细胞白血病的实验室特点有白细胞计数高、嗜酸和嗜碱性粒细胞增多、骨髓不同阶段髓细胞分化和巨核细胞增多;免疫组化提示CD68,髓过氧化物酶,中性粒细胞碱性磷酸酶积分明显减低,Ph染色体或BCR/ABL融合基因阳性,而幼年型CCML的Ph染色体常为阴性。

Methods: 1. Leukemia cell lines HL-60、Jurkat、Molt-4 were grown in RPMI medium 1640 supplement with 10% fetal calf serum and 100U/ml benzylpenicillin and 100 U/ml streptomycin sulfate in a humidified atmosphere containing 5% of CO2 at 37oC.

用脂质体将测序正确的重组子转染至白血病细胞株HL-60、Jurkat、Molt-4中,用RT-PCR、Western Blot方法检测iASPP的表达以及用流式细胞仪检测细胞凋亡的变化状况。

Objective: To study the influence of Boswellia carteriiBirdw extractive of different concentrations on human Jurkat cell apoptosis at different time points.

目的 :检测不同浓度、不同时间作用下乳香提取物对人急性T淋巴细胞白血病细胞株Jurkat细胞的促凋亡作用。

Method8: The paPef, fOr the first time, studied the apoptosis or necrosis of K562cclls induced by bungarus multicinclus crude venom and several components frOmcrude venom by cation exchange chromatography\' through the quatitative analysis offlow cytometry as well as the qualitative analysis, such as inversed opticalmicroscopy, MTT method and fluorescent microscopy, and so on.

本卖验采用羧甲基纤维素C-52阳离子交换层析将银环蛇粗毒进行了若干毒素组分的分离纯化,并以流式细胞术定量分析为主,以倒置显微镜、MTT比色法、荧光显微镜等多种定性分析为辅,首次对银环蛇粗毒及其若干组分蛋白对人慢性粒细胞白血病K562肿瘤细胞的细胞杀伤作用和凋亡诱导情况进行了研究。

Objective To evaluate the efficacy of CAG treatment on patients with untreated acute myeloid leukemia and study its mechanism.

目的 观察含粒细胞集落刺激因子的预激方案在治疗初治急性髓细胞白血病中的疗效,并进一步研究其作用机制。

The move on the part of the agency and drug maker comes after a study appeared in Nature Medicine earlier this year reporting cardiotoxic side effects of the drug in 10 patients with chronic myelogenous leukemia.

FDA和该公司对此标签的改变,是因为自然医学期刊今年稍早的一篇报导,提到此药在10位慢性骨髓性白血病患之心脏毒性副作用的研究。

Sn with the content of 0.004% in the lithosphere is almost in presence of cassiterite and little in presence of Sn-contained sulfide. Since 1980s, the anticancer active study on organic complex compounds has attracted considerable attentions, it becomes another hot issue after the study on Pt. When time up to the year 1989, the anticancer active measurement of more than 2000 kinds of Sn-contained complex compounds have been carried out by Cancer Academy, U.S, with the results showing half of these Sn-contained complex compounds posses antileucocythemia(P388) activity. Thereafter, Sn-contained complex compounds synthesized by hydrothermal reaction also become a hot issue people focus on.

Sn在地壳中的含量为0.004%,几乎都以锡石的形式存在,此外还有极少量的Sn的硫化物。20世纪80年代以来,人们对Sn有机配合物抗癌活性的研究产生了浓厚兴趣,成为继顺铂之后又一活跃的研究热点,到1989年,美国国家癌症研究所对2000多种Sn的配合物进行了抗癌活性测定,结果表明,50%的配合物具有抗P388白血病活性,故水热溶剂热合成锡的配合物也成为人们的研究热点。

ObjectiveTo evaluate the inhibitory effect of different extracts from Cestrum nocturnum Linn..

目的探讨夜香树不同提取物对小鼠白血病细胞株L1210细胞的增殖抑制作用及机制。

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