白血病

Results The deˉtection ratio of heteroploidy in leukemia children was more than that in non-leukemia.

结果 白血病组异倍体检出率明显高于非白血病组。12例非白血病中4例为异倍体，其中2例癌变。

Results The deˉtection ratio of heteroploidy in leukemia children was more than that in non-leukemia.Four of12patients with non-leukemia were heteroploidy,2of4were precancerous lesion.

结果 白血病组异倍体检出率明显高于非白血病组。12例非白血病中4例异倍体，其中2例癌变。

Four of12patients with non-leukemia were heteroploidy,2of4were precancerous lesion.The S%of marrow cell of leukemia was significant lesser than that of control.Three acute lymphocytic leukemia were got CR,and its S%was more than that before therapy.

白血病组骨髓细胞S%明显低于对照组。3例接受治疗的急性淋巴细胞性白血病患儿达到完全缓解后，其S%明显高于治疗前，非白血病组的骨髓细胞周期与正常对照组差异无显著性。

Objective In order to explore the expression of the SH2 domain containing inositol 5′-phosphatase gene pro-oncogene and its impact on the prognosis in the patients with acute leukemia.

目的观察含有SH2结构域的肌醇5位磷酸酶基因在急性白血病患者的表达，评价SHIP基因的改变在急性白血病和慢性粒细胞白血病发病中的作用以及对预后的影响。

Methods Flow cytometry and CD45/Side scatter gating were used to have immunophenotyping of children's acute leucocythemia tested and to analyze antigenic expressions in 67 cases of children's acute leukemia.

方法选择67例儿童急性白血病，采用CD45/SSC双参数散点图设门法流式细胞术进行急性白血病免疫表型检测，分析儿童急性白血病细胞的抗原表达规律。

Expression of WT1 gene was revealed in all kinds of leukemia patients and associated with quantity of leukemic cells.

WT1基因在各类型白血病中均能表达，表达水平与体内白血病细胞的数量有关，亦与白血病的病程进展等相关。

In this study, we found out that linalool, a small-molecule compound, could inhibit the growth of various human lymphocyte leukemia cell lines significantly. Meanwhile, it showed little toxicity to normal hematopoietic cells. To determine effects of linalool on the growth of a serious of human leukemia cell lines and normal hematopoietic cells and to explore its possible mechanisms, we employed various technologies, including MTT assay, Flow cytometry, Human Cancer PathwayFinder II Gene Array, Western Blot, RT-PCR and so on.

我们在筛选抗肿瘤小分子化合物时，发现天然小分子化合物芳樟醇能明显抑制多种人淋巴细胞白血病细胞增殖，而对正常人骨髓造血细胞及外周血细胞的增殖没有明显的影响，为此我们用MTT技术、流式细胞术、肿瘤相关信号通路分析技术以及Western blot、RT-PCR等手段和方法探讨了芳樟醇对不同类型白血病细胞系及相应正常造血细胞中的影响情况，及其诱导白血病细胞凋亡的可能分子机制。

This study aimed to investigate the pathophysiology and therapy of multi-drug resistant model of minimal residual leukemia in mice.

为了方便研究多药耐药微小残留白血病的病理生理和治疗，采用携带绿荧光蛋白基因标记的小鼠多药耐药白血病细胞系P388/VCRG和DBA小鼠建立一个检测多药耐药微小残留白血病的动物模型。

Down-regulation of bcl-2 expression appears to play an important role in apoptosis of the differentiated leukemia cells induced by realgar.

雄黄通过影响白血病细胞bcl-2蛋白的表达，从而导致白血病细胞发生凋亡，这是其治疗白血病的重要分子机制。

In 9 patients with acute lymphocytic leukemia, all leukocyte histogram showed small cell unimodal distribution and expanded from small to middle cell areas.

方法对52例骨髓检查确诊为白血病（急性白血病46例，慢性白血病6例）患者行静脉采血，用KX-21N全血细胞仪进行全血细胞计数，观察红细胞、白细胞和血小板各参数检测结果和白细胞直方图分布变化。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。