白血病

Results There was significant differencePConclusion The dynamic change of reticulin myelofibrosis content in bone marrow can be an important reference for the efficacy and early sign of recurrence in acute leukemia.

结果 16例急性白血病患者治疗前后骨髓网硬蛋白纤维阳性例数有明显差异P结论骨髓网硬蛋白纤维含量的动态变化，可作为急性白血病患者判定疗效与预测早期复发的一个重要参考指标。

The peak of stimulatory action was at 36 hours and 72 hours post-rhIL-7 treatment respectively.

将白血病细胞与100ng／ml浓度rhIL-7在37℃，体积分数为5％CO〓，饱和湿度条件下分别孵育18小时、36小时、72小时和120小时，结果显示白血病细胞在rhIL-7诱导后18小时B7-1和B7-2的表达开始增加，到36小时和72小时达高峰。

If the U937 cell line had been first treated with retinoids for 24 hours, then with IFN-γ after washing, the differentiating activity could be enhanced the reverse of the use of the two agents in chronology displayed much lower synergistical effect.

以上研究结果不仅对研究单核系白血病细胞分化机制提供一个模式，进一步开拓YS904012联合IFN-γ用于诱导分化治疗单核系白血病提供理论依据。

Tryptase appears to be a myeloid-specific marker in acute leukemias. It isalso an independent prognostic marker for acute leukemias.

类胰蛋白酶可以作为髓系白血病的特异性标记物，是急性白血病独立的预后标志物。

Glucocorticoids are effective in inducing apoptosis via the uncharacterized mechanisms in many hematological malignancies. GC-induced apoptosis is initiated by, and strictly dependent upon, the interaction of GC with its receptor, the GR.

糖皮质激素(glucocorticoid，GC)通过与其特异性受体-糖皮质激素受体(glucocorticoid receptor，GR)结合，不仅可诱导未成熟胸腺细胞凋亡，而且对急性白血病细胞、淋巴瘤细胞、骨髓瘤细胞等均有促凋亡作用，诱发凋亡正是应用糖皮质激素治疗白血病的分子生物学基础。

The LDH positivity of untreated and relapsed ALL patients was higher than that of the remission.

LDH和HBDH可预测白血病的发生和转归及成为评价白血病预后的指标。

Within three years following-up, 5 patients with NHL were survival, but one case of NHL died at the 2 months after auto-PBSCT, one patient suicided. From 4 cases received allo-PBSCT, one patiant with NHL was died at 79 days later, one patient with chronic lymphoblastic leukemia was surviving, another 2 cases of acute lymphoblastic leukemia were dead at 17 months and 54 days respectively after allo-PBSCT.

随访3年，5例NHL患者无病生存，1例NHL患者于移植后2个月死亡，1例自杀；4例接受异基因造血干细胞移植的患者中，1例非霍奇金淋巴瘤移植后79天死亡，1例慢性淋巴细胞白血病患者无病生存，2例急性淋巴细胞白血病患者分别于移植后第54天、第17个月死亡。

The marrow between the pink bone trabeculae seen here is nearly 100% cellular, and it consists of leukemic cells of acute lymphocytic leukemia that have virtually replaced or suppressed normal hematopoiesis .

如图可见粉红色的骨小梁之间的骨髓几乎100%是细胞，是由急性淋巴母细胞性白血病的白血病细胞构成，这些细胞实际上替代或抑制了正常的造血作用。

Incontrast, berbamine had slight effect on normal bone marrow cells and its IC〓 value was 103.650± 10.257μg/ml which was 17.5-27.5 times higher than those of leukemic cells.

上述结果提示，小檗胺具有较广谱的抗白血病细胞的作用，白血病细胞对小檗胺的敏感性明显地高于正常骨髓单个核细胞。

Based on the above findings, it could be concluded that:(1) berbamine could obviously inhibit the cell proliferation and induce apoptosis in four different kinds of leukemic cell lines (including K〓, Jurkat, NB〓, HL〓 cells) in a time-and-concentration-dependent manner in vitro.

综上所述，我们认为：(1)钙调素拮抗剂小檗胺在体外除对HL〓细胞外，还对其它3种不同类型的白血病细胞株(K〓、Jurkat、NB〓)细胞具有明显的增殖抑制作用及明确的诱导凋亡作用，并呈时间-浓度依赖关系，诱导细胞凋亡可能是其抑制白血病细胞增殖的主要方式之一。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。