白血病

To investigate the morphological changes of megakaryocytes with nuclear extrusion and nucleocytoplasmic separation, the morphological characteristics of megakaryocytes in peripheral blood films, bone marrow smears, and bone marrow biopsies from 4 newly diagnosed patients with primary myelofibrosis, myelodysplastic syndrome, myeloblastic leukemia with maturation (M2) and erythroleukemia (M6) were studied by using light microscope.

为了观察巨核细胞逸核和胞核胞质连体分离的形态学变化，用光镜观察4例初诊血液病患者的血片、骨髓涂片和骨髓切片中巨核细胞形态特征。4例初诊血液病患者为1例原发性骨髓纤维化，1例骨髓增生异常综合征，1例急性粒细胞白血病部分成熟型(M2)和1例红白血病(M6)。

Methods: The expression of Livin mRNA was measured in 91 AL and 17 chronic myelocytic leukemia patients by semi-quantity reverse transcription polymers chain reaction.

采用半定量逆转录-聚合酶链反应检测91例急性白血病和17例慢性粒细胞性白血病患者Livin mRNA的表达水平， 21名健康人的标本作正常对照。

To appraise effect of the home-made recombinant human granulocyte colony stimulating factor in the mobilization peripheral blood stem cells. From 2001 to 2005, 20 patients undergoing autologous peripheral blood stem cell transplantation were enrolled, 11 males, 9 females, 11 patients with acute myelocytic leukemia, 5 patients with acute lymphocyte leukemia, 3 patients with malignant lymphoma, and 1 patient with multiple myeloma.

为评估国产重组人粒细胞集落刺激因子在动员外周造血干细胞的效果，选择2001/2005收治的20例自体外周血造血干细胞移植患者，男11例，女9例，其中急性髓细胞白血病11例，急性淋巴细胞白血病5例，恶性淋巴瘤3例，多发性骨髓瘤1例。

Methods: The expression of Livin mRNA was measured in 91 AL and 17 chronic myelocytic leukemia patients by semi-quantity reverse transcription polymers chain reaction. 21 healthy adults were also measured as normal control.

采用半定量逆转录-聚合酶链反应检测91例急性白血病和17例慢性粒细胞性白血病患者Livin mRNA的表达水平， 21名健康人的标本作正常对照。

In an embodiment of the first aspect, the acute myelogenous leukemia is relapsed acute myelogenous leukemia.

在第一方面的实施方案中，所述急性髓性白血病是复发性急性髓性白血病。

In an embodiment of the third aspect, the malignancy is acute myelogenous leukemia.

在第三方面的实施方案中，所述恶性肿瘤是急性髓性白血病，例如，复发性急性髓性白血病。

Objective:The purpose of this paper is to clone novel leukemia associated gene in acute myeloid leukemia.

目的：发现新的白血病相关基因及探讨白血病的发生机制。

Methods The expression of CD87 was detected with flow cytometry in 54 AML patients and 20 acute lymphoblastic leukemia patients. The expressionsa of CD87 on U 937, HL-60 and K562 cells were also studied with FCM and reverse transcription-polymerase chain reaction during differentiation induced by phorbol myristate acetate in vitro.

应用流式细胞术检测了54例急性髓性白血病及20例急性淋巴细胞白血病患儿CD87的表达，还用FCM及逆转录-聚合酶链反应法检测了U937、HL-60、K562细胞在氟波酯作用下诱导分化过程中CD87表达的改变。

The Swedish Acute Leukemia Registry covers 98% of all patients with AML (nonacute promyelocytic leukemia) diagnosed in 1997 to 2005 (n = 2767), with a median follow-up of 5 years, and reports eligibility for intensive therapy, performance status, complete remission rates, and survival.

瑞典急性白血病注册研究覆盖了1997至2005年间诊断的98％ AML患者（非急性早幼粒细胞白血病）（2767例），中位随访5年，并报告了强化治疗的适宜条件，体力状态，完全缓解率和生存率。

Nevertheless there have general positive expression of Wnt5a in cases of nonmalignant hematologic diseases.

在31例血液病标本及髓系白血病细胞株中，除ALL外，有明显的Wnt5a表达缺失或降低，而非恶性血液病例中Wnt5a表达普遍呈阳性，提示Wnt5a的表达下调可能与髓系白血病的发生有关。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。