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白血病

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Yelodysplastic syndromes,as a disease of dyspoiestichematopoietic stem cell,have a disturbance of DNA synthesis,cellsdifferentiation and some leudemic characterization.It's marrow cell displaylike megaloblastic change,so we postulated that folate receptor have adifference of both quantitative and quanlititive in megalolbastic anemia,MDSand lenkemia.

DS作为异常干细胞克隆性增生疾病,在DNA的合成及细胞分化异常,表现出白血病的某些特征和骨髓细胞具有不同程度的巨幼变,因而我们推测巨幼贫、白血病和MDS的叶酸受体不但有量的改变,而且有质的变化。

Of conclusion leukaemia patient outside configuration of week blood white blood cell and structural change can pass VCS parameter to determine mensurably, if partial parameter is neuter distributinging breadth of bead cell volume, lymphocyte is average bulk is leukaemia the sieve is checked, diagnosed new index.

结论白血病患者的外周血白细胞形态和结构变化可以通过VCS参数定量地测定,部分参数如中性粒细胞体积分布宽度、淋巴细胞平均体积是白血病筛查、诊断的新指标。

AIM: To investigate the effects of artemisinin on apoptosis and differentiation of classic human acute monoblastic leukemia cell line U937 and to study the possibility of treatment of leukemia with artemisinin.

目的:通过青蒿素对经典人白血病细胞系U937的作用研究,探索青蒿素治疗白血病的可能。

In vitro, studies demonstrated that new retinoids in combination with IFN-γ could induce monoblastic leukemia cells to differentiate and inhibit their proliferention.

本文研究了NB4细胞株和新鲜急性早幼粒白血病细胞在新维甲类R9158、R8923、R9123和YS904012作用后的生物学特性变化;并且在初筛的基础上,选用R9158和YS904012与IFN-γ联合使用,研究对U937细胞株和6例原代单核系白血病细胞的增殖分化作用。

Results Twenty-seven cases (12.8%) were MK antigen positive with the higher positive rates in hybrid acute leukemia(45.5%) and acute monoblastic leukemia(24.1%).

结果 27例(12.8%)表达MK;AML亚型中以杂合急性白血病和急性单核细胞白血病(M5)表达最高,分别为45.5%和24.1%。

Acute monocytic leukemia is a distinct subtype of acute myeloid leukemia with characteristic biology and clinical features.

急性单核细胞白血病(AML-M5)是一类具有独特生物学和临床特征的急性髓细胞白血病

In one type of AML, called acute monocytic leukemia, the leukemia cells are more likely to invade the lining of the spinal canal or brain.

与急性髓细胞白血病的其他亚型相比,急性单核细胞白血病患者的肿瘤细胞更容易侵入椎管或脑内。

Methods Four patients with chronic myeloblastic leukemia and 4 with acute myeloid leukemia received allo-BMT with graft from 1 - 3 HLA-mismatched related donors.

方法4例慢性粒细胞白血病和4例急性髓性白血病患者接受人类白细胞抗原1-3个位点不相合骨髓移植,用阿糖胞苷、环磷酰胺和全身照射或马利兰进行预处理。

Methods The expression and change of TF and TFPI were detected in the peripheral venous blood samples from 20 normal controls, and 78 patients with haematological malignancies—34 patients with acute leukemia, 12 with chronic myeloblastic leukemia, 12 with non-Hodgkin lymphoma, 7 with multiple myeloma, 6 with myeloproliferative disorders, and 7 with myelodysplastic syndrome, by enzyme linked immunosorbent assay. After that, the correlation of TF and TFPI were analyzed.

选择正常对照组20例,恶性血液病组78例,其中急性白血病34例,慢性粒细胞白血病12例,非霍奇金氏淋巴瘤12例,多发性骨髓瘤7例,骨髓增殖性疾病6例;骨髓增生异常综合征7例。

Methods Magnetic resonance imagings of pelvis and femur were performed on 28 adult patients first diagnosed as acute granulocytic leukemia and 16 diagnosed as chronic myeloblastic leukemia based on morphology,immunophenotype and cytogenetic analysis. Twenty age-matched healthy volunteers were selected as controls. Results MRI of bone marrow in all patients were obviously different from those in controls.

方法搜集经细胞形态学、免疫学及遗传学分型综合分析确诊的成人初诊急性粒细胞白血病28例及慢性粒细胞白血病16例,所有患者均行骨盆及股骨中上段MRI检查,选取20名年龄匹配的健康志愿者作为对照组。

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