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白蛋白

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Clau (5, 10, 20〓) was bound to rat plasma a greater extent than clau, while in rabbit plasma the reverse was the case. By Scatchard plots using bovine serum albumin, clau had a higher equilibrium constant and the greater numbers of binding sites than its antipode.

在与大鼠血浆蛋白的结合中,clau的结合率平均为28.37±0.31(n=3,三个剂量5,10,20μM),clau的结合率平均为38.05±2.61(n=3),clau结合率低于clau;而在与兔血浆蛋白的结合中,clau的结合率平均为47.21±4.91(n=3,三个剂量),clau的结合率平均为41.43±5.21(n=3),clau的结合率略高于clau;在与牛血清白蛋白的结合中,clau的结合率也高于clau,立体选择方向与兔血浆蛋白结合相同,而与大鼠血浆蛋白结合相反,提示存在种属差异;在与系列浓度的牛血清白蛋白结合中,通过Scatchard作图法求得蛋白结合点数和平衡常数;在clau,N和K分别为90.02±35.76和5.326±1.196(n=4);在clau,N和K分别为59.92±20.39和4.203±1.250(n=4),两者的比值分别为1.50和1.27;进一步说明clau对映体的蛋白结合存在立体选择性差异。

Results摘要: The incidence rates of renal dysfunction, shock, cardiovascular failure and gastrointestinal hemorrhage, the score of acute physiology and chronic health evaluation Ⅱ and the frequencies of pulse and breath in the severe hypoalbuminemia group were all higher than those in the mild hypoalbuminemia group (P<0.05 or P<0.01). The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P>0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P<0.01) in the later stage of SAP.

结果摘要:重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组(P<0.01,肝功能衰竭发生率两组比较无统计学差异;Ranson评分及Balthazar CT评分两组间比较,差异无统计学意义(P>0.05);重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ(acute physiology and chronic health evaluationⅡ, APACHEⅡ)评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组(P<0.05或P<0.01;重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P>0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P<0.01) in the later stage of SAP. Conclusion: Hypoalbuminemia in the early stage can accelerate the deterioration in pathophysiology of SAP.

结果:重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组(P<0.01,肝功能衰竭发生率两组比较无统计学差异;Ranson评分及Balthazar CT评分两组间比较,差异无统计学意义(P>0.05);重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ(acute physiology and chronic health evaluationⅡ, APACHEⅡ)评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组(P<0.05或P<0.01;重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

Results: The incidence rates of renal dysfunction, shock, cardiovascular failure and gastrointestinal hemorrhage, the score of acute physiology and chronic health evaluation Ⅱ and the frequencies of pulse and breath in the severe hypoalbuminemia group were all higher than those in the mild hypoalbuminemia group (P<0.05 or P<0.01). The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P>0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P<0.01) in the later stage of SAP.

结果:重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组(P<0.01,肝功能衰竭发生率两组比较无统计学差异;Ranson评分及Balthazar CT评分两组间比较,差异无统计学意义(P>0.05);重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ(acute physiology and chronic health evaluationⅡ, APACHEⅡ)评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组(P<0.05或P<0.01;重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

The complications in the early stage, related parameters, and the incidence rate of infection and mortality in the later stage were evaluated respectively. Results: The incidence rates of renal dysfunction, shock, cardiovascular failure and gastrointestinal hemorrhage, the score of acute physiology and chronic health evaluation Ⅱ and the frequencies of pulse and breath in the severe hypoalbuminemia group were all higher than those in the mild hypoalbuminemia group (P<0.05 or P<0.01). The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P>0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P<0.01) in the later stage of SAP.

结果:重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组(P<0.01,肝功能衰竭发生率两组比较无统计学差异;Ranson评分及Balthazar CT评分两组间比较,差异无统计学意义(P>0.05);重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ(acute physiology and chronic health evaluationⅡ, APACHEⅡ)评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组(P<0.05或P<0.01;重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

The interaction between three small flavoind drug molecules, which are apigenin, galangin and genistein, and BSA is investigated with fluorescence spectroscopy using the drug's quenching on the endogenous fluorescence of serum albumin.

采用荧光光谱法,利用药物对牛血清白蛋白自身内源荧光的猝灭,研究了芹菜素、高良姜素和染料木素这三种黄酮药物小分子与牛血清白蛋白分子间的相互作用,研究发现药物分子与牛血清白蛋白分子之间发生了有效的静态猝灭。。。

In its protein has the albumin,谷蛋白, mellowly dissolves theprotein, the amino acid and so on, always tonic which prolongs thelife by our country people achievement.

其蛋白质中有白蛋白、谷蛋白、醇溶蛋白、氨基酸等,历来被我国人民作为延年益寿的补品。

According to the fluorescence measurement results from mixed solution, the association constant estimated for thioridazine hydrochloride-BSA binding and the number of the binding site with Scatchard analysis were 1.2×104 L/mol and 0.98, respectively.

将盐酸硫利达嗪与牛血清白蛋白以不同比例混合并在37 ℃下培养,以流动注射透析采样技术从混合液中分离出游离盐酸硫利达嗪,在线氧化为强荧光化合物后测定其浓度;应用Scrathard方程分析所测数据,求得盐酸硫利达嗪和牛血清白蛋白的结合常数为1.2×104 L/mol,结合位点数为0.98;根据热力学参数推断,盐酸硫利达嗪与牛血清白蛋白之间以疏水作用力为主;进一步基于荧光猝灭现象和Fster非辐射能量转移理论,得到盐酸硫利达嗪小分子与牛血清白蛋白之间的能量转移效率( E =0.497)和结合距离( r 0=3.27 nm)。

Equimolar BSA and hemin were combined in vitro to form hemalbumin based on the vivid property of bovine serum albumin, of which the peroxidase activity was examined .

鉴于血清白蛋白分子的活泼性,在体外将牛血清白蛋白(bovine serum albumin,BSA)与氯化血红素以相同摩尔量结合制成血红白蛋白,测定了其过氧化物酶活性。

Humanm Seroalbumin ,Albumin,Human Serum Albumin

别名: 血清白蛋白,人血白蛋白白蛋白

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

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