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白细胞的形成

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MLL fusion genes likely co-opt normal MLL functions in blood cells, leading to the overproduction of white cells and leukemia.

融合后的基因含有正常MLL功能,这会导致白细胞过度增生,最终形成白血病。

Beijing 100034,China(The School of Oncology,Beijing Institute for Cancer Research,Beijing Medical University,Beijing 100034,China)(The School of Oncology,Beijing Institute for Cancer Research,Beijing Medical University,Beijing 100034,China)Abstract : Objective In order to study the effects of ATP on U937 cells. Methods Cell culture,flow cytometry,HE staining,Nigrosine staining and electron microscopy were used.

应用ATP(0.23g/L)作用于人白血病细胞U937,(1)用白细胞计数器每日计数细胞和计算抑制率;(2)用流式细胞分析仪文献检测 ATP对U937细胞周期改变和凋亡的影响;(3)苏木精-伊红染色和电子显微镜文献检测凋亡小体的形成过程;(4)用苯胺黑染色文献检测凋亡小体的生命本性。

Methods The formation of mouse-tail scale epidermis were used as the epidermis parakeratosis model,different groups of mouse were treated with rhIL-11or methotrexate.

采用小鼠尾部鳞片表皮颗粒层形成模型,不同组别的小鼠给以白细胞介素-11或甲氨蝶呤,观察其对鼠尾鳞片表皮颗粒层和血清IL-2含量的影响。

Fibrin exudation, pulmonary interstitial incrassation, thrombosis of pulmonary artery, hemorrhage and gore were found. Conclusion: MR enhanced pulmonary perfusion can diagnose pulmonary embolism.

病理显示:梗死区可见大量的纤维素渗出,肺间质增厚,动脉腔内可见红细胞和血栓形成,其周围白细胞浸润伴肺淤血,部分可见点状出血及肺淤血。

Methods Models of leucocytopenia induced by irradiation were prepared by 60Coγ-ray and by cyclophosphamide injection. The shengbaiyin was administrated orally. The white blood cell counts, reticulocyte count, the number of nucleated bone marrow cells,T cell transformation indices, activity of tunmor necrosis factor and interleukin-6(IL-6) in blood of leukopenia mice on the 5th, 10th, 15st day after chymisty therapeutics were checked.

用60Coγ照射和注射给予环磷酰胺的方法形成骨髓抑制和免疫低下小鼠模型,中药生白饮合剂给予口服,以外周血白细胞、骨髓有核细胞、淋转指数以及细胞肿瘤因子、白细胞介素-6(IL-6)活性为观察指标。

the hip knee joint replaces the technique the deep phlebothrombosis, are cause the fibrin, the red blood cell under each kind of factor function as well as not the isometric blood platelet and the white blood cell in the vein the clustering process, after is the hip knee joint replaces the technique, most common complication.

髋膝关节置换术后的深静脉血栓形成,是在各种因素作用下导致纤维蛋白、红细胞以及不等量的血小板和白细胞在静脉内形成凝块的过程,是髋膝关节置换术后最常见的并发症。

Results After onset of reperfusion, the adhesion of platelet to endothelia was observed at veins of pial vessel. they distributed as tiny spots, 30~60 minutes after reperfusion, we observed the vacuole formation in endothelial cells of artery and thrombosis could be seen at the injurious area.

结果 再灌注后即刻,软脑膜细静脉内有白细胞和血小板粘附,呈星点状分布;再灌注(30~60)min,可观察到小动脉和细动脉内皮形成的空泡和血栓形成。

PTX at tenuates the ALI induced by LPS or sepsis in rat. The therapeutic effects of PTX include:improve oxygenation, at tenuate pulmonary edema formation, enhance animal survival in sepsis-induced ALI. The mechanisms may related with the effects of PTX inhibiting the chemotaxis, migration, activation of inflammatory leukocytes, diminishing the production of active oxygen, and inhibiting inflammatory cytokine release partly.

4PTX对大鼠内毒素性ALI及脓毒症性ALI均有一定的防治作用,主要表现在改善动脉血氧合,减轻肺水肿形成,提高脓毒症性ALI大鼠的存活率等方面,其机理可能与抑制白细胞趋化与激活,减少肺内白细胞渗出及活性氧产生,一定程度上抑制炎性细胞因子生成等有关。

It also reduced the formation of platelet-leukocyte conjugates,both in unstimulated and adenosine diphosphate-stimulated bloodsamples at 3%–4% end-expiratory sevoflurane concentrationsused to maintain anesthesia.

七氟醚呼末浓度为3%-4%时无论用还是不用二磷酸腺苷刺激的血标本中血小板-白细胞结合物的形成均减少。

Besides, the decrease of local or systemic levels of skin-derived antileukoproteinase also contributes to the formation of pustules.

另外,局部或全身皮肤抗白细胞蛋白酶水平降低也促进脓疱的形成。

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