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In order to develop a safe and effective immunoadjuvant to enhance the immunity and resistance of animals against infection, a novel CpG Oligodeoxynucleotides containing 11 CpG motifs was synthesized and inserted into the VR1012 plasmid, designated as VR1C. Then the recombinant VR1C was entrapped with Chitosan nanoparticles prepared by the method of ionic cross linkage, and employed to inject muscularly 3-weeks old Kunming mice; the blank VR1012 packed with CNP and saline were used to inoculate mice as the control groups. 28 days after inoculation, all mice were orally fed with 0.4ml 2x108CFU/ per mouse virulent hemorrhagic enteritis E. coli to challenge the resistance against infection.

为研制安全高效免疫调节剂增强动物免疫抗病能力,本实验设计合成含11个C pG基序的寡聚核苷酸,重组构建含CpG的VR1012质粒(VR1C);制备壳聚糖纳米颗粒包裹重组质粒(CNP-VR1C),肌注接种3周龄昆明小白鼠,设壳聚糖包裹空质粒和生理盐水对照组;接种后28天口服大肠杆菌攻毒观察小鼠天然免疫的变化和对强毒感染的抵抗力,Sandwich ELISA测定血清免疫球蛋白和白细胞介素含量。

Results Albuminuria was detected in 6.2% of subjects, reduced renal function in 3.0%, hematuria in 0.8%, and non-infective pyuria in 0.09%.

结果 在2310例资料完整的居民中,白蛋白尿的患病率为6.2%,肾功能下降的患病率为3.0%,血尿或非感染性白细胞尿的患病率为0.87%。

On October 31, 1992, Lewis knocked out Canada's hard-punching Donovan "Razor" Ruddock in two rounds for the No. 1 contender's position in the WBC world rankings.

在1992年10月31日,刘易斯淘汰了两轮的争夺第一的白细胞在世界排名的位置,加拿大的硬冲多诺万"剃刀"拉多克。

In its fifth year the WBC traveled to Trieste, Italy, the home of Italian coffee and quality espresso.

在其第五个年头的白细胞前往意大利的里雅斯特,意大利的咖啡和咖啡的质量回家。

OBJECTIVE:To determine umbilicus blood levels of interleukin-6(IL- 6),tumor necrosis factor-alpha and nitric oxide in neonatal HIE and elicit their roles in pathogenesis,so as to provide theoretical basis for improving HIE prognosis.

目的:旨在研究 HIE患儿脐血白细胞介素- 6( IL-6)、肿瘤坏死因子-α与一氧化氮的变化,并探讨其在 HIE发病机制中的作用,为进一步改善 HIE的预后提供理论依据。设计:以诊断为依据的病例对照研究。

We conducted the current study to define within the spectrum of the neutrophilic dermatoses a group of patients with an urticarial rash clinically and a neutrophilic dermatosis histopathologically.

我们运用目前的研究在嗜中性皮肤病的范围内来定义临床上的一类荨麻疹和组织病理学的一类嗜中性白细胞性皮肤病。

Human leukocyte antigen-G is a neoclassical human leukocyte class Ⅰ b antigen which was observed to be restrictively expressed by the fetal-maternal inter-fate on the extravillous cytotrophoblast.

人类白细胞抗原-G(human leukocyte antigen-G, HLA-G)属于非经典的HLA-Ⅰ类抗原分子,早期的研究发现HLA-G的表达仅局限于母胎界面的绒毛外细胞滋养层。

Objective To provide experimental data for choosing IAT in clinical application, we investigated and compared biophysical properties and oxygen affinity of red blood cells following IAT and homologous RBCs in erythrocytic concentrates reserved for 10 to 14 days.

目的 研究使用IAT技术回收处理后红细胞的生物物理性质和携氧功能的变化,并与库存10—14天的去白细胞悬浮红细胞相比较,为临床选择应用IAT技术的安全性提供实验依据。

AIM: To find the susceptible or resistant genes of H pylori infectionin Bai-ethnic children of Kunming,and to explore the immunogenetic mechanism of H pylori infection.

目的:探讨昆明白族儿童幽门螺杆菌(Helicobacter pylori,H pylori)感染与人类白细胞抗原-DQA1(HLA-DQA1)等位基因的相关性,寻找是否存在与H pylori感染相关的易感基因或抵抗基因,从免疫学的角度探讨H pylori感染的免疫遗传机制。

To analyze the leucocytes image by using wavelet, we bring forward the idea of detecting leucocytes karyon. Through analyzing deeply, we realize the fast-time leucocytes image detection.

基于小波包分解的白细胞图像处理,提出了细胞胞核提取的基本思想,进行了深入的理论研究和实际分析,实现对胞核边缘快速而有效的提取。

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这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

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