白细胞的

ELANE -related neutropenia includes congenital neutropenia and cyclic neutropenia, both of which are primary hematologic disorders characterized by recurrent fever, skin and oropharyngeal inflammation (i.e., mouth ulcers, gingivitis, sinusitis, and pharyngitis), and cervical adenopathy.

ELANE 相关性嗜中性白细胞减少症包括先天性嗜中性白细胞减少症和周期性嗜中性白细胞减少症，这两种都是主要的血液疾病，以反复发烧、皮肤和口咽发炎（指口腔溃疡、牙龈炎、鼻窦炎和咽炎）以及颈部淋巴结肿大为特征。

Objective To study the relationship between cytokine and development of Graves' disease through measurement of their level changes during antithyroid drug treatment.

目的：测定格雷夫斯病患者血清肿瘤坏死因子-α、白细胞介素-1、白细胞介素-2、白细胞介素-6水平及在抗甲状腺药物治疗过程中的变化，探讨其与格雷夫斯病发生发展之间的联系。

In 6 patients with chronic myeloid leukemia, all of them presented very high white blood cell counts （〉45 × 10^9/L） and represented completely wider and larger unimodal distribution of leukocyte histogram （100- 450 fl）, among them 83.3 % cases were extremely higher （〉 100 × 10^9/L）.

慢性粒细胞白血病患者白细胞总数均〉45 10^9／L，其中83.3％的患者白细胞总数异常增高（〉100 10^9／L），白细胞直方图均呈形状单一而分布广泛（100-450fl）的大细胞峰图形。

Results Erythrocyte count, hemoglobin concentration and hematocrit of all the patients with malignant digestive tumor decreased, mean corpuscular volume and mean corpuscular hemoglobin increased, arid there was inconspicuous change in total leukocyte count. The indications of megaloblastic anemia and proliferative anemia in bone marrow hemogram were found in the patients. It was common that the percentage of neutrophils was higher and that of lymphocytes was lower than that of the normal controls.

结果 消化道恶性肿瘤患者的红细胞计数、血红蛋白、红细胞压积均减少，平均红细胞体积、平均红细胞血红蛋白量增高，均表现为巨幼细胞性贫血，骨髓象呈增生性贫血改变，而白细胞总数的变化较小，白细胞分类，中性粒细胞百分比超过正常范围与淋巴细胞百分比低于正常范围者多见，血小板数异常远较血红蛋白与白细胞为少，但36例肝癌患者中28例出现血小板减少。

Nodosus Pilin gene, the ovine IL-2 gene with synthesized primers with EcoR1 and BamH1 recognition sequence at 5'and 3'end respectively was amplified and cloned from the peripheral blood of ovine.

从健康绵羊血中分离白细胞，用TRIZOL试剂盒提取绵羊白细胞RNA，以RNA为模板，用设计OviIL-2的引物进行RT-PCR和PCR，扩增出设计有BamHl和EcoRl限制性酶切位点的绵羊白细胞介素2。

METHODS: Female BALB/c mice were treated with CCK-8 and keyhole limpet haemocyanin, splenocytes were acquired and incubated in vitro with KLH restimulation, the productions of Th1 cytokines, interferon-γ, interleukin-2 and Th2 cytokines, IL-4, IL-5 in cell culture supernatants were detected by enzyme-linked immunosorbnent assay. The mRNA expressions of IFN-γ, IL-2, IL-4 and IL-5 in splenocytes were detected by reverse transcription-polymerase chain reaction. The levels of Th1 antibody IgG2a and Th2 antibodies IgG1 in serum were also detected by ELISA.

给予BALB/c小鼠钥孔戚血蓝蛋白免疫同时体内给予不同剂量的CCK-8，酶联免疫吸附试验检测其脾细胞培养上清中Th1型细胞因子γ-干扰素、白细胞介素-2（IL-2）和Th2型细胞因子白细胞介素-4（IL-4）、白细胞介素-5（IL-5）水平，逆转录聚合酶链式反应法检测脾细胞中IFN-γ、IL-2、IL-4、IL-5 mRNA表达；ELISA法检测血清中Th1型抗KLH抗体IgG2a和Th2型抗KLH抗体IgG1水平。

Objetive:To investigate the histopathological features and detect the mutation of JAK2V617F in PV、ET and IMF;to analyze the effects of the stages of myelofibrosis and the mutation on the number of leucocyte in PV and ET patients;Methods: the morphological features of 69 patients who dignosed in the first time were studied by HGF and Gomori stains ; the mutation of JAK2V617F was detected in 38 blood or marrow samples of PV、ET and IMF patients by real-time PCR;the effects of the stages of myelofibrosis and the mutation on leucocytes were analyzed;Results: Different stages of reticulin were observed in 15 PV and 15 ET patiens'marrow sections,and the cytosis、the pleomorphism and the bone trabecula side location of megakaryocytes were observed in all PV、ET and IMF patients;the means of leucocyte in patients with and without JAK2V617F were 20.4×109/Land 11.4×109/L respectively;the P value was 0.367 as comparing the leucocytes among different stages of reticulin increasing.

目的：探讨PV、ET、IMF患者的骨髓病理特点并且检测JAK2V617F突变的发生率，分析骨髓中纤维增生程度以及JAK2V617F对PV、ET患者白细胞数的影响；方法：69例初诊患者的骨髓切片经HGF染色以及Gomori染色后进行形态学研究；并利用real-time PCR法测38例患者的骨髓或者外周血的JAK2V617F突变；分析骨髓切片中纤维组织增生程度以及JAK2突变对患者白细胞数的影响；结果：15例PV和15例ET患者的骨髓切片中可以观察到不同程度的纤维组织增生，所有PV、ET、IMF患者骨髓病理中可见到巨核细胞增多、巨核细胞多形性改变以及巨核细胞定位于骨小梁旁；12例PV、4例ET、4例IMF中检测到JAK2V617F；有突变和无突变患者发病时白细胞数均值分别为20.4×109/L和11.4×109/L，比较不同纤维增生程度的PV、ET患者的白细胞数均值，P值为0.367。

Further,with indirect immunohistochemistry technique,CD25(IL-2 receptor or IL-2R) cross-reaction has been identified on lymphocyte membrane of Ctenophaxyngodon idellus and Trionyx sinensis using mouse monoclonal antibody directed against Human Leucocyte Differentiation Antigen CD25(IL-2R).

进一步用抗人白细胞分化抗原CD25(IL-2受体，简称IL-2R)单克隆抗体进行免疫组化交叉反应提示草鱼、中华鳖淋巴细胞膜上含有与人类IL-2R类似功能和结构的物质。关键词：白细胞介素-2；白细胞介素-2受体；发育和比较免疫学；草鱼；中华鳖

Unfortunately, practical methods of safely and effectively transfusing adequate numbers of granulocytes or other white cells are not yet available to prevent infection that occurs as a result of low white cell count.

遗憾的是，安全有效地输入适量的粒性白细胞或其它白细胞尚不能防止感染，这样就会出现白细胞数量的减少。

As with red cells and platelets, these transfusions should be irradiated prior to transfusion, but should not be treated with leukoreduction filters, as this would defeat the purpose of transfusing white cells.

与红细胞和血小板输注一样，粒细胞输注前也必须进行辐射处理，但不能经过减白细胞过滤，因为这样会破坏白细胞输注的目的。白细胞通过标准血液过滤器，除去其中的颗粒物和凝结的血液成分，但保留白细胞。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。