白细胞

Bisexual worms were perfused out from the liver of infected mice between 10 minutes and 48 hours after medication. Tegumental surface alternations were observed and became rather apparent 1～2 hours after medication. Major surface alterations included pronounced swelling, wrinkling, tough junction and fu...

结果表明，干给小鼠药后10分钟，两性血吸虫皮层即有变化，1～2小时后已十分明显，主要变化为水肿，皮层褶嵴紧密连接、融合，形成大量球状物或小泡，感觉器肿大、破溃，以及皮层糜烂、剥落和白细胞附着于皮层损害处等。

To observe the change of behavior index and mensurate the contents of plasma CORT, CRH and ACTH by using radiation immunity methods, and observed the change of immunity function by testing IL-2 and lymphocyte multiplication produced by spleen cell. At the same time, the author examined the change of thalamencephalon CRH mRNA and pituitary ACTH mRNA.

观察行为学指标的变化，利用放免法测定血浆皮质酮、下丘脑促肾上腺皮质激素释放激素和血浆促肾上腺皮质激素的含量，并通过脾细胞产生白细胞介素2（IL-2）水平和淋巴细胞增殖试验观察大鼠免疫功能的变化，同时检测大鼠下丘脑CRH mRNA和垂体ACTHmRNA含量变化。

The path-physiological mechanism of ICH is complicated, which includes the high intracranial pressure caused by hematom mechanical pressure, the lesion by the decrease of regional cerebral blood flow surrouding the hematom, even regions adjacent to the hematom, Meanwhile, the materials released from hematom including ferrohemoglobin, thrombase, plasma protein and platelet, leucocyte, glusate not only directly injury neurons but also blood brain barrier.

脑出血的病理生理学机制复杂，其中包括血肿的机械压迫所造成的持续的脑缺血性损害；血肿分解后产生的血红蛋白、凝血酶、血浆蛋白、血小板和白细胞、谷氨酸、自由基等毒性物质不仅可直接损伤神经元，而且可损害血脑屏障加重脑水肿。

Topotecan is an effective agent for SCLC when used as monotherapy or in combined treatment, but myelosuppression such as leucopenia and thrombopenia was relatively severe. Although it has been recommended as a second-line agent for recurrence of sensitive SCLC, more clinical trials are needed to define its role in first-line treatment.

拓扑替康治疗小细胞肺癌有确切临床疗效，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，但具有相对高的致白细胞和血小板下降的骨髓毒性，已被认为是治疗化疗敏感的小细胞肺癌患者复发的二线推荐药物，但是作为一线用药仍然需要更多的实践来证实。

Conclutions Topotecan is an effective remedy for treatment of small cell lung cancer, both single topotecan and combined regimen has the same effect as the traditional first-line regimen, though myelo-suppression such as leucopenia and thrombopenia is more sever, the adverse effect is tolerated. Though it has been recommended as second-line agent for chemo-therapy sensitive small cell lung cancer, there needs more clinical studies to verify its role in first-line.

结论拓扑替康是在小细胞肺癌的治疗中有确切临床疗效的药物，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，虽具有相对高的致白细胞和血小板下降的骨髓毒性，但毒副作用可耐受，已经被认为是治疗对化疗敏感的小细胞肺癌患者的二线推荐药物，但是作为一线用药仍然需要更多的临床证据来证实。

Meta-analyses showed that the response rate of TP (topotecan + cisplatin) regimen had no significant difference compared with EP regimen (etoposide + cisplatin) with OR 0.83 and 95%CI 0.63 to 1.09, but myelo-suppression such as leucopenia and thrombopenia was more severe with TP regimen; the response rate of monotherapy with topotecan was similar with that of CE (carboplatin + etoposide) regimen with OR 0.59 and 95%CI 0.22 to 1.60; the response rate of TEP (topotecan + etoposide + cisplatin) regimen was comparable with that of EP regimen with OR 1.37 and 95%CI 0.82 to –2.28, but myelosuppression and anemia were more severe with TEP regimen; the response rate with OR 0.97 and 95％CI 0.60 to –1.57, median time to progression with WMD –2.32 and 95％CI –5.72 to 1.09 and median survival time with WMD –1.65 and 95％CI –7.13 to 3.83 of IV topotecan were similar to those of oral topotecan, while neutropenia was more severe with IV topotecan.

Meta分析结果表明，TP 方案与EP方案的反应率相似 [OR 0.83， 95%CI (0.63，1.09)]，但具有相对高的致血小板下降的骨髓毒性；单药拓朴替康与CE方案的反应率相似 [OR 0.59， 95%CI (0.22，1.60)]；TEP方案（拓扑替康＋足叶乙甙＋顺铂）与EP方案的反应率相似 [OR 1.37， 95%CI (0.82，2.28)]，TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案；口服拓扑替康与静脉滴注拓扑替康的化疗后反应率 [OR 0.97， 95％CI (0.60，1.57)]、中位疾病进展期 [WMD –2.32， 95％CI (–5.72， 1.09)]、中位生存期 [WMD –1.65， 95％CI (–7.13，3.83)] 相似，口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

Changes in IL-2/IL-2R system in 25 patients with thyrotoxic Graves disease and 20 eu-thyroids were investigated and compared with those of 15 normal controls. The thyrotoxic patients showed a high concentration of serum sIL-2R and a large amount of circulating IL-2R-α- cells but a decreased production of IL-2 by PBMC. However, these abnormalities had a tendency to become normal with improvement of the disease.

Graves病的发生是环境、遗传和免疫等多种因素综合作用的结果＊淋巴细胞的免疫调节异常是其中的一个重要原因，而白细胞介素-2（IL-2）及其受体在维持正常T细胞功能和兔疫调节方面发挥关键作用。

Interleukin-2(IL-2) activity by thymocyte (C57BL/6-8 mice) proliferation assay and fibroblast(L929 fibroblasts) cytotoxicity assay has been found in supernatant of mitogen-stimulated splenocyte cultures of grass carp Ctenophaxyngodon idellus, Chinese soft-shelled turtle Trionyx sinensis.

摘 要：用刀豆蛋白A刺激诱导草鱼和中华鳖脾细胞，收集细胞培养上清液，用小鼠胸腺细胞增殖试验和对小鼠L929细胞系杀伤试验检测上清液中白细胞介素-2(简称IL-2)活性。

In the experiment cell viability of HUVEC and PMBC were assessed by MTT assay, survival rate of PMN was assessed by trypan blue staining.

其中白细胞与内皮细胞的粘附在血栓形成过程中具有重要意义，是启动缺血后炎性损伤的关键。

Objective: To investigate the correlation between tryptase, IL-29 and clinical pathological properties of esophageal carcinoma.

目的：探讨食管癌组织中类胰蛋白酶和白细胞介素－29(interleukin-29， IL-29)的表达及其与食管癌的相关性。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。