白屈菜红

PURPOSE: To study the effect of Chelerythrine on glucosyltransferase and extra-cellular synthesis of water-insoluble glucan of Streptococcus mutans.

目的：研究白屈菜红碱对变形链球菌葡糖基转移酶和细胞外水不溶性多糖合成的影响。

Chelerythrine suppressed the translocationof PKC- and - and blocked the improvement of cardiac functionand ATP.

白屈菜红碱抑制了 PKC-和-的易位，阻滞了心功能和 ATP 的改善。

PKC and mitochondrial KATP channels were inhibited with chelerythrine and 5-hydroxydecanoate pretreatment, respectively.

试验中使用白屈菜红碱、5-羟基癸酸分别抑制心肌蛋白激酶 c 、线粒体 ATP 钾离子通道。

Chelerythrine could inhibit the glucosyltransferase and extra-cellular synthesis of water-insoluble glucan of Streptococcus mutans.

白屈菜红碱对变形链球菌葡糖基转移酶和细胞外水不溶性多糖的合成具有显著抑制作用。

The Langendorff model was used, and isolated perfusedrat hearts were separated into untreated, isoflurane, chelerythrine plus isoflurane, and chelerythrine groups.

使用 Langendorff 模型，离体灌注大鼠心脏被分为未治疗组，异氟醚组，白屈菜红碱加异氟醚组和白屈菜红碱组。

MethodsNormal human mesangial cells were divided into 4 groups: a control group(N, 5 mmol/L glucose), a high glucose group (H, 30 mmol/L glucose), a PKC inhibition group (P, 30 mmol/L glucose plus 10-5mol/L chelerythrine chloride), and an mannitol group (M, 5 mmol/L glucose plus 25 mmol/L mannitol).

将NHMC分4组： N组（对照组，5 mmol/L葡萄糖）；H组（高糖组，30 mmol/L葡萄糖）；P组（抑制剂组，30 mmol/L葡萄糖+10-5mol/L白屈菜红碱）；M组(甘露醇组，5 mmol/L葡萄糖+25 mmol/L甘露醇)。

Chelerythrine and 5-hydroxydecanoate abolished cardioprotection in both SEVO and EtOH cardioprotected hearts.

白屈菜红碱、5-羟基癸酸在 EtOH 组和 SEVO 组中均能减弱原本的心肌保护作用。

Reactive oxygen species scavenger N-2-mercaptopropionyl glycine, protein kinase C antagonist chelerythrine, and mitochondrial KATP channel closer 5-hydroxydecanoate each blocked protection from 2 minutes of acidosis as they did for postconditioning.

活性氧簇清道夫N-2硫丙酰甘氨酸、蛋白激酶C拮抗剂白屈菜红碱、线粒体KATP通道关闭剂5-hydroxydecanoate都可以阻断两分钟的酸中毒和后条件的保护作用。

METHODS: The Chelerythrine was used as the experimental group with concentrations ranging from 24.4μg/ml to 390.6μg/ml prepared with BHI broth medium with contained 2% glucose, and BHI culture medium was used as the control group.

采用二倍稀释法，用含2%蔗糖的脑心浸萃液肉汤琼脂液体培养基，将白屈菜红碱稀释为从390.6μg/ml到24。

Till today, we have extracted and purified alkaloids from from Macleaya Cordata, Chelidonium Majus L., Tripterygium Wilfordii Hook f., Sedum Sarmentosum Bunge, and obtained pure sanguinarine, ethoxysanguinarine, oxysanguinarine, chelidonine, chelerythrine, ethoxychelerythrine, chelilutine, chelirubine, protopine,α-allocryptopine,β-allocryptopine, coptisine, berberine, corysamine, bocconine; triptolide, tripdiolide, triptonide, wilforddine; N-methylisopelletierine, dihydro-N-methylisopelletierine, sarmentosin etc.

我们对博落回、白屈菜、雷公藤、垂盘草等天然植物进行了大量的提取和分离研究；并分离出了血根碱、乙氧基血根碱、氧化血根碱、白屈菜碱、白屈菜红碱、乙氧基白屈菜红碱、白屈菜黄碱、白屈菜玉红碱、原阿片碱、α-别隐品碱、β-别隐品碱、黄连碱、小檗碱、沙明碱、博落回碱，雷公藤内酯醇、雷公藤内酯二醇、雷公藤内酯酮、雷公藤碱，N-甲基异石榴皮碱、二氢- N-甲基异石榴皮碱、垂盘草甙等单体。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐