癌的

On the other hand, flow cytometry was employed to detect the action of paclitaxel to cell cycle and apoptosis. Reverse transcription polymerase chain reaction is employed to detect the influence of paclitaxel on Survivin mRNA expression. The purpose of the study is to provide theoretical basis to carcinogenesis, progress, metastasis, angiogenesis and clinical chemotherapy of paclitaxel on TSCC.

采用流式细胞仪检测紫杉醇对舌癌细胞细胞周期的影响及应用逆转录聚合酶链反应(reverse transcription polymerase chain reac-tion，RT-PCR)检测紫杉醇对舌癌中Survivin mRNA的影响，为研究舌鳞癌的发生、发展机制，舌癌的转移及新生血管形成，及临床应用紫杉醇抗舌癌提供理论依据。

The mechanisms of apoptosis of skin squamous cell carcinoma induced by IFN-γand ATRA Introduction and objective Skin squamous cell carcinoma is a malignant neoplasm derived from epidermal keratinocyte and squamous cells of skin appendant organ .It is one of the most common skin carcinoma, and the incidence rate of SCC is 20% in malignant non-melanoma. It is a common disease that seriously harms health of people in our country, so we should pay more attention to it.

维甲酸、γ-干扰素诱导皮肤鳞状细胞癌SCL-1细胞凋亡的机制研究前言与目的皮肤鳞状细胞癌(squamous cell carcinoma，SCC，简称鳞癌)是起源于表皮角质形成细胞或附属器鳞状上皮细胞的一种恶性肿瘤，是常见的皮肤恶性肿瘤之一，其发病率约占全部非黑素细胞癌的20％。

The mechanisms of apoptosis of skin squamous cell carcinoma induced by IFN-γand ATRA Introduction and objective Skin squamous cell carcinoma is a malignant neoplasm derived from epidermal keratinocyte and squamous cells of skin appendant organ .

维甲酸、γ-干扰素诱导皮肤鳞状细胞癌 SCL-1细胞凋亡的机制研究前言与目的皮肤鳞状细胞癌(squamous cell carcinoma，SCC，简称鳞癌)是起源于表皮角质形成细胞或附属器鳞状上皮细胞的一种恶性肿瘤，是常见的皮肤恶性肿瘤之一，其发病率约占全部非黑素细胞癌的20％。

objective to analyze the ct appearance of thyroid carcinoma and the differential diagnosis of various thyroid disease.methods 83 cases of thyroid carcinoma and 119 cases of various benign disease with surgical and pathologically proved were analyzed retrospectively.results the ct findings of 83 cases of thyroid carcinoma include:ill defined nodules boundary (n=62),irregular necrosis(n=59),cystic(n=23),"peninsula" enhancing tubercles around the tumour(n=25),"mastoid" tubercles around the tumour(n=11),calcification(n=55) including large scale(n=27) and local(n=28),trachea invasion(n=15),neck or supraclavicular lymph node metastasis(n=27),the accurate of ct to differentia benignancy from malignancy on thyroid disease was 93.6%(189/202).conclusions "peninsula" enhancing tubercles was the characteristic sing of thyroid carcinoma,"mastoid" enhancing tubercles or large scale calcification was the affirmative sign,the ct signs was vary useful to differentiating thyroid disease.

摘 要］目的：分析甲状腺癌的ct表现及鉴别诊断要点。方法：回顾性分析经手术病理证实的83例甲状腺癌和119例甲状腺良性病变的ct表现，归纳总结不同病变的ct特征。结果：83例甲状腺癌中：边界不清62例，不规则坏死59例，囊性变23例，出现"半岛状"强化结节25例，"乳头状"强化结节11例，钙化55例(其中弥漫性钙化27例、局灶钙化28例)，侵犯气管15例，颈部或锁骨上淋巴结肿大27例，ct对甲状腺病变的良恶性鉴别诊断符合率93.6%(189/202)。结论："半岛状"强化结节是甲状腺癌的特征性表现，"乳头状"强化结节及弥漫性钙化可做为甲状腺癌的肯定性征象，掌握各种甲状腺病变的ct表现特点，对病变的定性诊断及鉴别诊断具有重要意义。

The transitional cell carcinoma of the bladder is liable to plant and recrudescence.

本研究选取COX-2、原癌基因HER-2、抑癌基因p53进行探讨，目的在于了解COX-2，HER-2，p53在膀胱移行细胞癌发生发展中其蛋白产物表达情况以及它们可能存在的相关性，以期对膀胱移行细胞癌的诊断、预后、监测、治疗提供一定理论指导作用。

Down-regulated expression of PTEN and up-regulated expression of VEGF〓 were considered as two important events in tumorigenesis of ovarian cancer and could act as molecular markers to indicate the pathobiological behaviors of ovarian cancer. Decreased PTEN expression and increased VEGF〓 expression were closely associated with tumorigenesis and pathobiological behaviors of ovarian endometrioid and serous cancer respectively. Reduced expression of PTEN gene might be involved in carcinogenesis and progression of ovarian cancer by up-regulating the VEGF〓 expression to enhance angiogenesis.

在卵巢癌组织中PTEN基因mRNA表达下调和VEGF〓基因mRNA表达上调是卵巢癌发生的重要分子事件，可作为反映卵巢癌病理生物学行为的指标，且分别与卵巢内膜样癌和浆液性囊腺癌的发生和病理生物学行为关系密切；PTEN基因mRNA表达降低可能通过上调VEGF〓基因mRNA表达促进新生血管形成，进而参与卵巢癌的发生和侵袭。

The incidence of bone metastases varied with different lateral of lun g cancer (P.01).The incidence of adenocarcinoma (72.41%) was higher than squam ous carcinoma(43.48%)(P.05).Multiple metastatic lesions accounted for 93.1%(8 1 cases) and solitary 6.9%(6 cases),with an average of 6.39 loci per patient.

肺腺癌的阳性率72.4 1%，肺鳞癌的阳性率为43.48%，腺癌较鳞癌容易发生骨转移(P.05)。87例骨转移患者中81 例为多发病灶(占93.1%)，6例为单发病灶(占6.9%)，每例患者的平均病灶数为6.39个。

It was reported that the infection of HPV subtypes 16 and 18 might be related with the development of anal cancers and carcinomas of genitalia, such as cervix, vulvae and penis.

作为一种呈乳头瘤样增殖的性传播性疾病，尖锐湿疣与人类乳头瘤病毒的感染有关，特别是与HPV6、11、16、18型感染有关，其中HPV6、11型致癌性小，而HPV16、18型有高度致癌性，与肛门癌和宫颈癌、外阴癌、阴茎癌等生殖器癌的发生密切相关。

XIAP expression could not be affected by the apoptotie inductions mediated by death receptor and mitochondria pathway in both cell lines.

通过对肾癌组织和细胞的研究，提示抗凋亡的XIAP在肾癌组织中呈肿瘤进展依赖性增高、在抗凋亡的肾癌细胞高表达，在肾癌细胞抗凋亡机制中发挥重要的作用，影响肾癌对凋亡信号的敏感性，使肾癌细胞获得生存发展的优势，从而促进肾癌的进展，并产生对诱导凋亡药物的抵抗；应用基因克隆和Tet-Off基因可控性表达系统技术构建的肾癌细胞XIAP稳定表达细胞系，对深入研究XIAP在肾癌抗凋亡中的机制，具有实用意义。

Objective: To investigate the expression of MAGEA1 and MAGEA3 protein in the development of head and neck squamous cell carcinoma, as well as in the head and neck squamous cell carcinoma and adjacent tissues. It will help to know the correlation of the two proteins in head and neck squamous cell and provide satisfactory and safe surgical margin of squamous cell carcinoma.

目的：探讨MAGEA1及MAGEA3蛋白在头颈部鳞癌的发生过程中的表达以及在头颈部鳞癌及癌旁组织中的表达情况，了解其与头颈部鳞癌发生的相关性，并为鳞癌手术安全切缘的范围提供理论依据。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。