癌化

Objective: To investigate the expression of JAK, ERK and Cyclin D proteins in squamous-cell carcinoma of tongue.

目的：探讨磷酸化JAK和磷酸化ERK及CyclinD1蛋白在舌鳞状细胞癌发生、发展中的作用及其表达的相互关系。

Results: The PCNA mean labelling index was 48.84％± 13.63％, and the apoptotic labelling index was12.26‰± 5.20‰. The Kaplan-Meier survival curves showed that the postoperative survival time of the patient was shorter when the tumor infiltrated to the adventitia of esophagus,with lymph node metastasis, without keratinization, PI ≥ 40％ or AI＜10‰. Using forward multivariate Cox regression analysis, only the parameters of pN category and PI could be verified as independent prognostic factors.

结果：36例手术切除的食管鳞癌组织平均PCNA表达指数(PCNAlabellingindex，PI)为48.84％±13.63％，细胞凋亡指数(apoptosisindex，AI)为12.26‰±5.20‰；PI升高与患者年龄小、分化程度低、有淋巴结转移和肿瘤进行性浸润呈正相关，而AI升高与分化程度高、角化明显呈正相关；绘制Kaplan－Meier生存曲线，发现病变侵及食管外膜、有淋巴结转移、无角化、PI≥40％或AI＜10‰的患者术后生存率明显降低；COX比例风险模型分析，发现只有淋巴结转移和PI是影响预后的独立因素。

Objective: To investigate and stratify the prognostic factors of cervical squamous cell carcinoma according to the corresponding prognostic risks and to establish a prognosis-predictive system.

目的：探讨影响宫颈鳞癌预后的因素，将其按预后风险水平层别化，并建立预后预测系统以指导个体化治疗方案。

A portion of ductal cells and individual serous acinic cells of the minor salivary gland also expressed Fas not only in membranous but also in cytoplasmic pattern.

结果发现，在正常鼻咽粘膜表面及隐窝的假复层纤毛柱状上皮细胞胞膜、部分小涎腺的导管上皮和个别浆液性腺泡上皮细胞的胞膜和胞浆Fas阳性表达；鳞状化生上皮的表层细胞胞膜有Fas表达，但基底细胞未见Fas表达；浸润的淋巴细胞也不表达Fas.45.9%（17/37）的鼻咽非角化性癌Fas阳性，但只有不足10%的癌细胞胞膜微弱表达Fas。

Recent studies showed that deamidation of Bcl-xL, an anti-apoptotic protein, regulates cellular response to DNA damage. This Bcl-xL deamidation induced by cisplatin appears to be mediated by p53 and Rb.

目前有研究显示在DNA损伤下，抗死蛋白Bcl-xL的去胺基化可调控细胞反应，而在抑癌基因p53和Rb 突变的癌细胞中也发现抗癌药物cisplatin的处理会导致Bcl-xL 的去胺基化。

To reveal chemokines mediating the celiac metastasis of epithelial ovarian carcinoma by way of investigating the chemokine receptor expressions in serous epithelial ovarian carcinoma cell lines and tissues, and the corresponding ligand expressions in membrana abdominis.

本研究通过分析浆液性上皮性卵巢癌细胞系和组织趋化因子受体的表达，及腹膜间皮细胞相应配体的表达，以揭示趋化因子介导上皮性卵巢癌腹腔内转移机制。

Currently we call metaplastic ca if the cases have classic of metaplasic components, such as spindle cells, squamous cells, chondro-osseous.

一般，如果病例中有典型的化生成分，如：梭形细胞，鳞状细胞、软骨，我们则称之为化生性癌。

Howeer, complex solid and cystic masses were proen to be metaplastic carcinomas, malignant phyllodes tumors, and mucinous carcinomas, which may represent malignant masses with cystic components.

然而复杂实性囊性肿块被证实为化生性癌、恶性叶状肿瘤、粘液癌，代表为带有囊性成分的恶性肿块。

To find the significance of oncogenes in the development of prostate cancer.

肿瘤的发生是多步骤的，涉及到多种癌基因和抑癌基因的改变［'］，我们采用免疫组化法对50例前列腺癌组织中bcl－2、P和c－erb－B。

The expression of some oncogenes in the cells was examined by means of chromosomal pattern analysis and immunohistochemistry.

应用染色体核型分析和免疫组化方法，分析原代细胞核型以及癌基因与抑癌基因的表达。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。