癌前期的

Objective: To investigate the relationship between human papillomavirus and cervical carcinoma and cervical intraepithelial neoplasia.

目的：探讨人乳头瘤病毒与宫颈癌及癌前期病变的相关性。

The progress intervals between stages of the disease were estimated using left-censored and interval censored Markov chain models with a 6-year follow-up simulation. Results showed an annual preclinical incidence rate of 5.7 per 1000 for the high-risk group. The mean sojourn time was 1.90 years (95% CI=1.18-4.86). The proportion of interval case increased with the screening interval.

本研究自1995年至1996年10月止利用台湾地区12家大型医院，锁定出2629名高危险群妇女接受乳癌筛检，第一年筛检到的31名病病例之实证资料，推估得妇女乳癌之临床症前期发生率为每年每千人5.7人（0.0057/年），依据这些资料。

Study leader, Dr Bjorn Strander, senior consultant in obstetrics and gynaecology at the University of Gothenburg, Sweden, said:"It must be considered a failure of the medical service when women participate in screening, their pre-cancerous lesions are found and they subject themselves to treatment of those lesions, presumably participate in follow-up programmes, and still develop invasive cancer."

瑞典研究员表示，有宫颈癌早期征兆，而接受治疗的妇女在十年之后会患有高危疾病。他们说，癌前期病灶患者应该在至少25年里有规律地经行子宫颈涂片检查。对于那些患有原位癌而接受治疗的英国妇女，最新的指导方案是建议他们每年进行检查，而且检查要持续十年。对于13.3万妇女的研究报告刊登在英国医学期刊上。英国，年龄在25至49的妇女，每三年不时的进行子宫颈癌常规检查，而后直到64岁，每五年检查一次。它可以检测出位于子宫颈表层可能转化成癌的细胞变化情况。如果监测到异常细胞，它们将会被监控，破坏，而且移除。

Oral cancer has become a serious health issue in Taiwan, and it is believed that oral submucous fibrosis and leukoplakia are precancerous lesions.

口腔癌已成为国人严重的健康课题，口腔黏膜下纤维化及口腔白斑症被认为是口腔癌的癌前期病变，因此研究这些口腔黏膜疾病的致病因对於口腔癌的预防和治疗有其重要性。

Degradation is the most important factor during transformation from tumor in situ or pre-invasive tumor to invasive tumor.

浸润是转移的起始步骤，从原位癌或浸润前期发展到浸润性癌的转化中，最主要的因素是其下基底膜的破坏。

We conducted a nested case-control study within four large, prospectie cohorts to inestigate whether prediagnostic plasma leels of IGF-I, IGF-II, and IGFBP-3 were associated with pancreatic cancer risk. Plasma leels in 212 cases and 635 matched controls were compared by conditional logistic regression, with adjustment for other known pancreatic cancer risk factors.

我们在四个大型的前瞻性群组中进行了巢式病例对照研究以调查是否诊断前期的血浆IGF-I， IGF-II，和 IGFBP-3水平与胰腺癌风险相关。212病例和635配对对照的血浆水平使用条件逻辑回归进行比较，使用另外已知的胰腺风险因子进行调节。

We studied the expression of PTEN gene and its mRNA on a series of 146 cases of primary laryngeal carcinoma patients, 40 cases of precancerous lesion and 26 cases of vocal fold polyp by tissuechip by ,immunohisto- chemistry and in situ hybridization method.

结果：PTEN蛋白在声带息肉中无表达，癌前期病变以及喉癌组织的阳性表达率分别为40.00%、43.15%。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失