癌

Objective: To study the expression characteristics of cytokeratin 19 (CK 19) in usual cutaneous carcinomas.

目的：了解角蛋白19在皮肤鳞癌和皮肤基底细胞癌组织中的表达特徵。

Basal cell carcinoma and squamous cell carcinoma are common cutaneous tumors which are related to multiple factors.

基底细胞癌和鳞状细胞癌是常见的皮肤肿瘤，其发病与多种因素有关。

Objective: To assess the diagnosis and treatment of the cystic.

目的：探讨囊性肾癌的诊断与治疗，以提高对囊性肾癌的认识和诊断率。

Laparoscope combined with cystoscope for the treatment of upper tract transitional cell carcinoma is safe and effective.

对肾盂癌和中、上段输尿管癌采取腹腔镜联合膀胱镜行肾、输尿管全长切除可闭合输尿管末端，避免术中肿瘤种植，是一种安全有效的手术方式。

The general rule I learned from my cytopathology fellowship is that if a thyroid neoplasm looks not perfect for papillary carcinoma, follicular neoplasm, or Hurthle cell neoplasm, think about medullary carcinoma.

我从细胞同行那学习的经验是这样的，如果一个甲状腺肿瘤不完全象乳头癌，不完全象滤泡性肿瘤，也不完全象嗜酸细胞性肿瘤，这个时候，可能就是髓样癌。

Results (1) The total RNA, reverse transcription product and fluorescence labeled cRNA were all of high quality;(2) There were 420 up-regulated genes and 552 down-regulated genes among 2-fold DEGs, including DKK1 (dickkopf homolog 1) which was 5-fold up-regulated;(3) The results of real time RT-PCR, using β-actin as an internal control, showed that the 2-ΔCt values of DKK1 in HCC, PCT and NLT were 0.089 504, 0.007 65 and 0.000 631 respectively.

结果 （1）配对组织总RNA质量高，反转录cRNA及荧光标记质量好；（2）2倍差异表达基因中，上调基因共420个，下调基因共552个，其中包括5倍上调基因DKK1；（3）以β-肌动蛋白为内对照的实时逆转录聚合酶链反应结果提示，DKK1在癌、癌旁和正常肝组织中的2-ΔCt值分别为0.089504、0.00765和

Methods A total RNA from ten cases of ovarian cancer and contral normal ovarian tissues were extracted by a single step method. The cDNA retro-transcribed from equal quantity mRNA derived from ten cases of ovarian carcinoma and normal ovarian tissues, which were labeled cDNA strand with Cy5 and Cy3 fluorescence as probes.

按一步法分别抽提10例人卵巢癌组织和对照正常卵巢组织的总RNA并纯化mRNA；分别从10例取等量的人卵巢癌组织和对照组织的mRNA分别混合后逆转录合成以Cy5和Cy3标记的cDNA一链做探针，混合后在含有8464点人类体细胞基因模板的表达谱cDNA芯片上进行杂交。

Methods］ A total RNA from 10 cases withovarian papillary serous cystadenocarcinoma and normal ovarian tissues were extracted by a single step method of gene chip. The cDNA retro?鄄transcribed from equal quantity mRNA derived from 10 cases with ovarian papillary serous cystadenocarcinoma and normal ovarian tissues. The cDNA strand was labeled with fluorescent Cy5 and Cy3(normal ovarian epithelial cells) as probes.

方法］ 采用基因芯片技术，按一步法分别抽提10例卵巢浆液性乳头状囊腺癌患者的癌组织和正常卵巢组织的总RNA并纯化mRNA；逆转录合成以Cy5荧光标记卵巢癌细胞和Cy3荧光标记正常卵巢上皮细胞的cDNA作为探针，在含有8 464点人类体细胞基因模板的表达谱cDNA芯片上进行杂交。

The five most common benign lesions were dermoid cyst and epidermoid cyst, cavernous hemangioma, lymphangioma, pleomorphic adenoma, orbital inflammation. The five most common malignant lesions were lymphoma, lacrimal adenoid cystic carcinoma, rhabdomyosarcoma, melanoma, sebaceous gland carcinoma.

位于良性病变前5位的分别是皮样囊肿及表皮样囊肿、海绵状血管瘤、淋巴管瘤、泪腺混合瘤、慢性炎症和炎性假瘤；位于恶性肿瘤前5位的分别是淋巴瘤、泪腺囊腺癌、横纹肌肉瘤、黑色素瘤、皮脂腺腺癌。

Recent study showed that the devitalization of DPC4 gene was present in nearly 50% of pancreatic carcinoma, which interrupted the TGF-βsignal pathway, so inactivation of DPC4 gene maybe one of the most important cause of pancreatic carcinoma. The present study was carried out to clarify the effect of DPC4 gene on human pareatic carcinoma cell line JF305, which can help us understand the growth and proliferation mechanism of pancreatic carcinoma and provide us the practical guidance on gene therapy of pancreatic carcinoma.

最新研究资料表明近一半的胰腺癌存在DPC4(deleted in pancreatic carcinoma)失活，进而使TGF-β信号传导途径中断，失去其对肿瘤细胞的抑制作用，导致细胞过度生长和增殖，因此DPC4的改变可能是胰腺癌发生、发展的重要原因之一[2]。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。