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The key to using aberrant energy metabolism as a way to enhance site affinity that specifically targets the cancerous tumor cells' microenvironment that produces measurable tumor selective alkalinization involves administering an alkaline composition that has little toxicity to normal healthy viable cells which preferentially targets and elevates the pH level of the tumor micro-environment, thus causing the non-viability and apoptosis of tumor cells.

可使用异常能量新城代谢来提高癌位置的亲和力,使癌进行具有可测性、可选性的碱化,从而专门改变癌细胞的微环境。其关键在于使用一种对正常健康活性细胞无毒性的碱性制剂,能优先提高癌微环境的pH水平,从而使癌细胞不具有生存能力,促使其凋亡。

Resulte: In 12 infective lesions, including purulent infection (4 cases) and tuberculosis (8 cases), the correct dignosis was made in 4cases by CR and in 11 cases by CT. In 16 soft tissue tumors, including lipoma (7 cases), fibrosarcoma (4 cases), hemangioma (1 case), neurofibroma (1 case), malignant fibrous histocytoma (1case), aggressive fibromatosis (1 case) and liposarcoma (1 case), the correct diagnosis was made in 3cases by CR and in 14 cases by CT. In 11 bone lesions, including fibrous dysplasia (7 cases), chondroma (2 cases), myeloma and cosinophilic granuloma (1 case), the correct diagnosis was made in 8cases by CR and in 10 cases by CT.

结果:感染组12例中(包括化脓性感染4例,胸壁结核8例),CR准确诊断4例,CT诊断11例;软组织肿组16例中(包括脂肪7例,纤维肉4例,血管、神经纤维、恶性纤维组织细胞、侵袭性纤维病和脂肪肉各l例),CR准确诊断3例,CT诊断14例;骨肿和肿样病变组11例中(包括骨纤维异常增殖症7例,软骨2例,多发性骨髓和骨嗜酸性肉芽肿各1例),CR准确诊断8例,CT诊断10例。

Our findings demonstrate that in conjunction with clinical and radiographic findings, immunohistochemical evaluation with a panel of D2-40, EMA, brachyury, and GFAP is most useful in distinguishing chordoid meningioma from chordoid glioma, skeletal myxoid chondrosarcoma, extraskeletal myxoid chondrosarcoma, chordoma, low-grade chondrosarcoma, and enchondroma. A lack of strong, diffuse S100 reactivity may also be useful in excluding chordoid meningioma.

我们的结果表明,结合临床和影像学资料,D2-40、EMA、brachyury和GFAP这样一个免疫标记组合就能很好地鉴别脊索样脑膜和脊索样胶质、骨的黏液样软骨肉、骨外的黏液样软骨肉、脊索、低级别软骨肉、内生性软骨。S100染色不强烈、不弥漫也有助于排除脊索样脑膜的诊断。

The malignant tumors included osteogenic osteosarcoma,metastasis tumor(six patients,two with pathologic fractures),chondrosarcoma,malignant fibrous histiocytoma (three patients,one with pathologic fracture),fibrosarcoma,and solitary myeloma.all patients received limb savage procedure with custom knee prosthesis including sevnteen cases of hinge joint and twentyone cases of posterior stability joints.

回顾分析我院接受定制型人工关节置换进行保肢治疗的股骨远端肿患者38 例,其中良性肿9 例,分别是骨巨细胞7例(复发性骨巨细胞5 例,骨折2例),骨巨细胞合并动脉样骨囊肿1 例,骨母细胞1 例;恶性肿29 例,分别是成骨性骨肉16 例,转移性肿6例(骨折2例),软骨肉2 例,恶性纤维组织细胞3例(骨折1例),纤维肉1 例,局灶性骨髓1 例。

Purposes: To observe intakes of 〓p-sodium-orthophosphate and 〓P-chromium- orthophosphate at various concentrations by brain gliomas cell; To make thorough inquiry of the inhibition to the SHG44 cell by 〓P-sodium-orthophosphate and 〓P-chromium-orthophosphate at various concentrations; To find out the regularities about the accumulation and elimination in the major organs of rats after inter-brain injection with 〓P-sodium-orthophosphate and 〓P-chromic-orthophosphate; To investigate the therapeutic effects of intert-injection with 〓p-chromium-orthophosphate on the neoplasia transplanted in the brain and hypoderma; To estimate the absorbed dose of the neoplasia body in rats after internal radiation; To study the pathological changes in the rat cells and tissues caused by the radiation exposure from 〓p.

目的:观察人脑胶质SHG44细胞对不同浓度的〓P-磷酸钠和〓P-磷酸铬的摄取;探讨不同浓度〓p-磷酸钠和〓p-磷酸铬对SHG44细胞生长的抑制;揭示〓p-磷酸钠和〓p-磷酸铬在大鼠颅内注射在时全身主要脏器的蓄积与排除规律;观察〓p-磷酸铬大鼠颅内体、皮下体内注射的治疗效果;估算大鼠体组织的吸收剂量;观察〓p照射引起的细胞及组织的病理学改变,为临床脑胶质内照射治疗提供实验依据和吸收剂量计算方法。

Results Of the 58 cases, 26 were inflammatory pseudotumors, 8 focal hyperplastic lesions, 7 hepatocellular adenomas, 7 lipomatous tumors, 5 cystadenomas, 3 tuberculosis, 1 harmatoma and 1 neurofibroma.

结果 58例中炎性假26例,局灶性增生性病变8例,肝细胞腺7例,脂肪类肿7例,囊腺5例,肝结核3例及错构和神经纤维各1例。

Results 5 cases of ependymocytoma, 3 cases of astrocytoma, 1 medulloblastoma hemangioblastoma in 10 cases of intra-medullary tumor; 36 cases of neurogenic tumor, 11 cases of spinal meningioma in 47 cases of subdural extramedullary tumor; 2 cases of neurogenic tumor strided over scleromeninx;2 cases of extradural metastatic tumor, 1 cestodiasis, 2 cases of epidural hematoma, which were mistaken for hemangioma before surgical operation and 1 vascular malformation in 4 cases of intraspinal nontumorous occupying lesion.

结果:10例髓内肿中,室管膜5例;星形细胞3例;血管母细胞1例;成神经管细胞1例。47例脊髓外硬膜下肿中,神经源性肿36例;脊膜11例。2例跨硬膜内外生长的神经源性肿2例。硬膜外的转移2例。4例椎管内非肿性占位性病变中,椎管内绦虫病1例;硬膜外血肿2例,术前误为血管;血管畸形1例。

Lateral tumors in adults often appear extraaxial and may simulate meningiomas of the cerebellopontine angle or tentorium, acoustic neuromas, ependymomas, glomus jugulare tumors or metastases, solid hemangioblastoma and choroid plexus papilloma.

位于外侧的肿经常表现类似于轴位病变,与桥小脑角区或幕下脑膜、听神经、室管膜、颈静脉球或转移、实性血管母、以及脉络膜乳头状相类似。

They were all right-handed.12 cases using conventional surgery were the control group(eight cases of glioma,3 cases of meningioma,1 case of brain metastases),eight cases of men,four cases of women;the average of 42 years old. The other patients were the experimental group(six cases of glioma,2 cases of meningioma, 2 cases of brain metastases,cavernous angioma 1 case),seven cases of men,four cases of women,the average of 45 years old.

其中12例设为常规手术对照组(胶质8例,脑膜3例,脑转移1例),男性8例、女性4例,平均年龄42岁,11例设为实验组(胶质6例,脑膜2例,脑转移2例,海绵状血管1例),男性7例、女性4例,平均年龄45岁。

Methods ICR Mice of tumor model was made by inoculated with tumor cells (S180, EAC, and Heps). The antitumor activity of brucine and its liposome was evaluated by tumor inhibitory ratio for S180 and Heps and life prolonging rate for EAC and Heps of mice with transplanted tumor.

用ICR小鼠接种S180、EAC腹水、肝Heps株造成相应的移植性荷小鼠模型,考察马钱子碱及其脂质体对实体模型(S180和Heps)小鼠的抑率和对腹水模型小鼠生命延长率的作用以研究两者的抗肿活性。

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