瘤

Objective:To establish a reliable model of human meningioma in vivo.

目的：探讨建立裸鼠移植脑膜瘤模型的方法，为脑膜瘤的基础研究提供实验依据。

Objective: To investigate the relationship between glioma and PGE2 and to find the possibility of indomethacin curing glioma.

目的：探讨脑胶质瘤与PGE2之间的内在联系，找出消炎痛类药物作为胶质瘤辅助治疗的可能性。

Histology revealed numerous xanthomatous cells in association with a few lymphocytes surrounding the follicular infundibulum, consistent with a diagnosis of xanthomatous Fox-Fordyce disease.

病理切片下可见毛囊漏斗部周围有大量黄色瘤细胞与少量淋巴球的浸润，在回顾相关的文献后我们诊断其为黄色瘤样型的福斯佛代斯氏病。

But the application of inoculant in field was blocked as the problem of nodulation competitiveness between inoculant strains and indigenous strains was not been solved completely.

尽管人们对这一问题已进行了大量的研究，但与根瘤菌结瘤基因的研究相比，我们对根瘤菌的竞争结瘤机制的认识仍非常有限。

Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P＜0.001.

结果：构建了带有HSV-tk基因的反转录病毒载体GINaTK，应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317，成为产病毒细胞PA317TK，用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞，命名为C6TK细胞，对GCV和ACV的敏感性分别高于亲本450倍和10倍；成功地建立了大鼠脑胶质瘤模型，并证实转染细胞C6TK的成瘤效应未改变，存活期约为15天；而经ACV治疗后，含有C6TK细胞的肿瘤生长明显被抑制，大鼠生存期延长为57.8±8.07天，尤其是采用PA317TK细胞混和治疗组和原位治疗组，肿瘤基本消失，大鼠生存期显著延长，混和治疗组存活120天以上，原位治疗组存活至71.4±36.1天。t检验，P值均小于0.001。

Results: GINaTK retroviral vector containing HSV-tk was constructed and transduced into PA317 retrovirus packaging cell by lipofectin (named PA317TK). Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P ＜0.001.

结果：构建了带有HSV-tk基因的反转录病毒载体GINaTK，应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317，成为产病毒细胞PA317TK，用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞，命名为C6TK细胞，对GCV和ACV的敏感性分别高于亲本450倍和10倍；成功地建立了大鼠脑胶质瘤模型，并证实转染细胞C6TK的成瘤效应未改变，存活期约为15天；而经ACV治疗后，含有C6TK细胞的肿瘤生长明显被抑制，大鼠生存期延长为57.8±8.07天，尤其是采用PA317TK细胞混和治疗组和原位治疗组，肿瘤基本消失，大鼠生存期显著延长，混和治疗组存活120天以上，原位治疗组存活至71.4±36.1天。t检验，P值均小于0.001。

Abstract］ objective to observe the effect on palpebral xanthelasma excision with the micrrergy intradermic suture.

摘要］ 目的观察改良睑黄色瘤切除术的应用效果。方法选择病灶＜10 mm以下的瘤体为手术观察对象，共22例（38眼）。

Objective: To investigate the effects and mechanism of adenovirus-bcl-xs gene on the inhibition of ascites tumor cells and survival rate of nude mice transplanted intraperitoneally with human ovarian carcinoma.

目的：研究重组腺病毒bcl-xs基因对卵巢癌细胞及其裸鼠移植腹水瘤的生长抑制作用和荷瘤裸鼠生存率的影响，同时探讨bcl-xs基因对于卵巢癌的作用机制。

There were 31 cases of intraspinal tumors. Conclusions Astrocytoma, embryonal tumors and craniopharyngioma are the most common types of CNS tumors in childhood.

椎管内31例。结论星形细胞瘤、胚胎性肿瘤和颅咽管瘤是最常见的儿童CNS肿瘤组织学类型。

In contract, the tumor tissue of control group kept morphology, tumor nodules composed of undifferentiated carcinoma, and some karyokinesis could be seen, some spotty necrosis were found occasionally in where the structure among tumor cells were loose associated very slight inflammatory response; At the 21 days after injected AdCMVIL-12, the tumor boundary of AdCMVIL-12-Ⅰ group were clear and felt hard by touch, section showed grey.

同期的对照组绝大多数肿瘤细胞形态完好，排列紧密，由大量未分化的肿瘤细胞组成并可见多个核分裂像，偶尔可见散在的点状坏死灶，瘤细胞之间结构松散，炎症反应很轻；AdCMVIL-12注射后第21天时，AdCMVIL-12-Ⅰ组的肿瘤组织经手摸感觉瘤体境界清楚、发硬，切面呈灰白色。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新