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In two series experiments by-pass nitrogen, amino acid passage to the abomasum, rureen metabolic parameters and nitrogen utilization were studied respectively.

利用四头装有胃和皱胃瘘管的阉公羊以及四头未装瘘管的阉公羊进行两系列实验,测定通过胃蛋白、皱胃氨基酸通过量以及胃消化代谢和氮的利用。

Through all this test analyse Pathogenicity and Immunological status of ALV-J Inner Mongolia strain, the result showed the infected chickens began to have pathological change of Myelcytomatosis at 3-week: the main pathological changes of acidophile myelocyte were found in bone marrow and between cardiac muscle fibers,and there were many granules in the hyalotome.This kind of oncocyte proliferated in every tissue at different amount, but the cells that proliferated in bone marrow, cardiac muscle fiber, oarium were much more than other tissue, and they often developed neoplasma. At same condition,there were no abnormalty advent in control group, In immunological aspect: the increase of lymphokine and ANAE positive cells showed cell-mediated immunity was strengthend during antineoplastic infection; the emergence of ALV-J antibody of ELISA suggest there was humoral immunity exist at the same time.

结果显示:脾脏PCR检测结果表明1、2两实验组均有阳性病例出现,而对照组全部为阴性,说明实验鸡体内已有ALV-J内蒙株感染;接种病毒后3周龄开始出现骨髓细胞病的病理变化:肝脏、脾脏有程度不同的肿大,镜下观察,骨髓内最早出现了与骨髓细胞相似、形态基本一致的大型圆形或椭圆形、胞核较大多为椭圆形、胞浆内含有大量嗜酸性圆形颗粒的髓细胞样细胞增生,随后通过血流细胞可转移到肝脏、心肌、卵巢或睾丸等组织并形成肿性病灶,而对照组没有出现明显病变;免疫状态方面:以脾脏淋巴因子和ANAE阳性细胞增多说明细胞免疫在抗肿感染过程中增强,ELISA检验实验鸡抗体出现阳性的结果表明同时也存在着体液免疫。

Abstract] objective to study the pathological features and histopathological type and differential diagnosis of hepatic focal nodular hyperplasia.methods the clinicopathological characteristics of 40 cases of fnh were studied.all were evaluted by use of paraffin embedded sections and he staining before light microcope observation.results there were 28 females and 12 males fnh patients whose age were from 16 to 62 years(median 41.3),all alpha-fetoprotein was negative and had no hepatitis history.25 cases were classic type showed characteristic central stellate fibrotic scar,composed of fibrous connestive tissue and tortuous blood vessels.8 cases were telangiectic type,the left were mixed type and adenomatoid type.conclusion fnh is a reactive proliferation of hepatic cells to local blood vessel anomalies,it is not realy a tumor.its differential diagnosis includes hepatic adenomatous hyperplasia nodule,hepatic anaplasia nodular hyperplasia,fibrolamellar hepatocellular carcinoma and hepatocellular adenoma.

目的 探讨肝局灶性结节性增生的病理形态特点、组织分型及鉴别诊断。方法分析40例肝局灶性结节性增生的临床资料,并采用石蜡包埋he染色光镜下观察其组织学特点。结果 40例肝局灶性结节性增生患者中,女28例,男12例,年龄18~62岁,平均年龄41.3岁,所有病例术前均无肝炎病史,甲胎蛋白阴性,组织学上25例为经典型,有特征性的中央纤维瘢痕,由纤维结缔组织及扭曲血管组成。8例为毛细血管扩张型,其余为混合型及腺样增生型。结论肝结节性增生是一种肝细胞对局部血管的异常反应性增生,并非真性肿,主要与肝腺样增生性结节、肝间变性结节状增生、肝纤维板层癌及肝细胞腺鉴别。

According to pathological examinations, 6 of 18 cases were with meningiomas, 6 with metastatic tumors, 4 with inflammatory granuloma, 1 with cavernous angioma, and 1 with glioma.

本组18例病理结果:脑膜6例,转移6例,炎性肉芽肿4例,海绵状血管1例,胶质1例。术后神经功能保护良好,无手术并发症及死亡。

The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma; therefore, a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy.

对於病理医师和临床医师来说,区分出这个纤维神经的变异型非常重要,因为异生细胞纤维神经在组识学上和细胞学上都非常类似肉,因此正确的诊断出这个纤维神经的变异型是必要的,因为临床上对於良性和恶性肿的治疗和肿行为表现是不同的。

The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma therefore , a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy .

对於病理医师和临床医师来说,区分出这个纤维神经的变异型非常重要,因为异生细胞纤维神经在组织学上和细胞学上都非常类似肉,因此正确的诊断出这个纤维神经的变异型是必要的,因为临床上对於良性和恶性肿的治疗和肿行为表现是不同的。

Oncolytic adenovirus H101 could replicate and cause oncolysis effects on glioblastoma U251 cells, it shows greater oncolysis effects and much more H101mRNA expression by enhanced virus tite or prolonged time.

1。溶病毒制剂H101对体外培养的人类胶质母细胞U251存在明显的抑制作用,能够在肿细胞内复制,并最终起到溶作用,并且胶质母细胞U251细胞内病毒的产量随时间的延长而增大。2。

Results:Of 22 cases, there were 8 benign stromal tumors, 2 malignant GISTs,3 lipomas,3 cysts,3 esophageal carcinomas,2 esophageal venous nubbles and 1 with no abnormity.

结果:22例患者中,良性间质8例,恶性间质2例;脂肪3例,囊肿3例,食管癌3例,食管静脉2例,未见异常发现1例。

The cancer therapy and composition for using the same of the present invention involves administering a therapeutically effective and non-lethal amount of a pharmaceutical composition to mammals in need of such a therapy and more specifically humans suffering from cancerous neoplasms and to prevent the formation and elimination of the hostile cancer viability zone and more specifically the tumor micro-environment which can help treat metastatic tumors and at sites other than a primary tumor site with site specificity for malignant cells that is not restricted by the type of cancer cell, including damaged or necrotized cells and tissues.

使用本发明制剂的抗癌疗法和制剂可以在需要此类治疗的哺乳动物,更确切一点,受癌折磨的人身上,使用疗效显著、剂量不致命的医药制剂。可以组织敌对癌生存区的形成,并加以消除,更确切一点,消除癌微环境,从而有助于治疗病毒转移性癌;消除当场有针对性地治疗不受癌细胞类型限制的恶性细胞,如受损或坏死的细胞和组织。

According to result of group I, II, HI, relationship of dry matter intake digestible energy intake , crude protein intake , ruminal degradable protein or ruminal undegradable protein with average daily gain of stall-feeding growing Boer goats were analyzed.

根据Ⅰ、Ⅱ、Ⅲ组试验数据得出波尔山羊干物质采食量、粗蛋白质采食量、胃降解蛋白、胃非降解蛋白及消化能采食量与羔羊日增重的回归关系如下: DMI=2.540△W+659.7(r=0.953,p.05) CPI=0.70△W+40.492(r=0.955,p.05) RDPI=0.213△W+65.06(r=0.856,p.05) UDPI=0.488△W-24.56(r=0.984,p.05) DEI=68.56△W+1074.9(r=0.924,p.05)根据回归方程,本研究提出了波尔山羊(3~5月龄)日增重0~250g的每日每只营养需要建议参数:即当预期日增重分别为0g、50g、100g、150g、200g、250g时,消化能日供给量分别为1.08MJ、4.50M3、7.93M5、11.36MJ、14.79MJ、18.21MJ,粗蛋白日供给量分别为40g、75g、110g、145g、180g、215g,胃降解蛋白日供给量分别为409、759、869、979、1089、1189,胃非降解蛋白日供给量分别为09、09、249、489、729、979。

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