瘢痕瘤

Abstract］ objective to study the pathological features and histopathological type and differential diagnosis of hepatic focal nodular hyperplasia.methods the clinicopathological characteristics of 40 cases of fnh were studied.all were evaluted by use of paraffin embedded sections and he staining before light microcope observation.results there were 28 females and 12 males fnh patients whose age were from 16 to 62 years（median 41.3）,all alpha-fetoprotein was negative and had no hepatitis history.25 cases were classic type showed characteristic central stellate fibrotic scar,composed of fibrous connestive tissue and tortuous blood vessels.8 cases were telangiectic type,the left were mixed type and adenomatoid type.conclusion fnh is a reactive proliferation of hepatic cells to local blood vessel anomalies,it is not realy a tumor.its differential diagnosis includes hepatic adenomatous hyperplasia nodule,hepatic anaplasia nodular hyperplasia,fibrolamellar hepatocellular carcinoma and hepatocellular adenoma.

目的 探讨肝局灶性结节性增生的病理形态特点、组织分型及鉴别诊断。方法分析40例肝局灶性结节性增生的临床资料，并采用石蜡包埋he染色光镜下观察其组织学特点。结果 40例肝局灶性结节性增生患者中，女28例，男12例，年龄18~62岁，平均年龄41.3岁，所有病例术前均无肝炎病史，甲胎蛋白阴性，组织学上25例为经典型，有特征性的中央纤维瘢痕，由纤维结缔组织及扭曲血管组成。8例为毛细血管扩张型，其余为混合型及腺瘤样增生型。结论肝结节性增生是一种肝细胞对局部血管的异常反应性增生，并非真性肿瘤，主要与肝腺瘤样增生性结节、肝间变性结节状增生、肝纤维板层癌及肝细胞腺瘤鉴别。

Methods 58 cases were operated upon microsurgery to resect the pseudoneuroma or cicatrix and to repair nerve.

对神经干连续性存在，而有神经膜内神经瘤或瘢痕形成之病例进行显微外科手术切除与重建治疗。

Objective To research the treatment of delayed developing compression syndromes caused by pseudoneuroma or cicatrix in nerve trunk intramembrane,and to evaluate the outcome.

目的 探讨神经干膜内由于假性神经瘤或瘢痕组织引起的迟发进行性神经卡压综合征的临床特点和治疗方法。

Methods 58 cases were operated upon microsurgery to resect the pseudoneuroma or cicatrix and to repair nerve.Results The time of nerve recovery ranged from several hours to six weeks.

中文摘要：目的探讨神经干膜内由于假性神经瘤或瘢痕组织引起的迟发进行性神经卡压综合征的临床特点和治疗方法。

Large numbers of experiments internal and external had confirmed both direct current and square pulse of distal end cathodal could improve peripheral nerve regeneration, because it could speed up transmigration, creeper, growth and development of cell Schwann, derivate growth of nerve fiber; it also increased blood capillary of epineurium, brood blood vessel, amendment ischemic of impaired nerve, it still could accelerate Wallerian

国内外大量的基础实验及临床研究都证实远端负极电流的直流电场及脉冲电场等均有促进周围神经再生的作用，认为其可加速Schwann细胞的游走、爬行及生长发育，诱导神经纤维的生长；电刺激还能促使神经外膜毛细血管数量增多，扩张血管，改善神经损伤段缺血状态，并加速Wallerian变性及崩解组织的清除，为Schwann细胞发育和髓鞘化过程提供充足的能量与物质，同时为神经轴突的再生提供良好的内环境；在神经断端出现瘢痕或神经瘤时，电刺激可增加神经纤维穿越瘢痕的能力。

The mRNA of CTGF, TGF-β1,ColⅠ and ColⅢ in neurofibroma tissue were over-expressed, whereas that in normal skin tissue was none or rare.

神经纤维瘤组织及瘢痕疙瘩组织中CTGF、TGF-β1、ColⅠ和ColⅢ的mRNA过表达，而正常皮肤组织无或仅有极弱表达。

Methods Specimens of neurofibroma tissue, keloid and normal skin were collected. The distribution and expression of CTGF was measured by immunohistochemistry. The mRNA expression of CTGF, TGF-β1,ColⅠ and ColⅢ was detected by reverse transcription- polymerase chain reaction. Expression of CTGF protein was measured by western blotting.

收集神经纤维瘤组织、瘢痕疙瘩组织及正常皮肤组织标本，免疫组化检测CTGF的表达，逆转录-聚合酶链式反应方法检测组织CTGF、TGF-β1、Ⅰ型胶原及Ⅲ型胶原 mRNA表达，Western blotting检测组织CTGF蛋白的表达。

The technique has obvious effects on mole, wart, spot, chloasma, coffee spot, face xanthoma, syringocystadenoma, wrinkle decrease in face and neck, dermatocyst, underarm odor, unhealthy tattoo eyebrow, and eye lines, removal of tattoo, removal of unnecessary hair, scar repair, and pigmentary hair nevus.

该技术在痣、疣、斑、黄褐斑、咖啡斑、脸黄瘤、汗管瘤、面颈部减皱、皮肤囊肿、腋臭、不良纹眉眼线、去纹身、去除多毛、修复瘢痕、色素性毛痣、太田痣等疗效显著。

B, Color Doppler scan of a Desmoid tumor in a previous scar revealing some vascularity in the lesion.

图16，A，以前疤痕处的硬纤维瘤。B，彩色多普勒扫描以前瘢痕处的硬纤维瘤病变处显示一些血管供应。

Methods Nuclear β-catenin expression was detected by immunohistochemistry in 77 lesions with desmoid-type fibromatosis and 171 other spindle cell lesions, including superficial fibrmoatosis (n=18), nodular fasciitis (n=36), keloid (n=16), scar (n=10), granulation tissue (n=9), synovial sarcoma (n=38), neufibroma (n=13), solitary fibrous tumor (n=12), gastrointestinal stromal tumor (n=10), low-grade myxofibrosarcoma (n=3), low-grade fibromyxoid sarcoma (n=3), and smooth muscle tumor (n=10). In addition, the immunohistochemical expressions of ER-α, ER-β and Ki-67 were examined in all of the lesions with desmoid-type fibromatosis. The nuclear immunohistochemical staining for nuclear βcatenin and ER-β was graded as high level (≥25% of cells), low level (5%-25%) or none.

采用免疫组织化学染色法检测77例韧带样型纤维瘤病和171例其它良、恶性梭形细胞病变（包括结节性筋膜炎36例、浅部纤维瘤病11例、瘢痕疙瘩16例、增生性瘢痕10例、肉芽组织9例、滑膜肉瘤38例、神经纤维瘤13例、孤立性纤维性肿瘤12例、胃肠间质肿瘤10例、低度恶性黏液纤维肉瘤3例、低度恶性纤维黏液样肉瘤3例及平滑肌肿瘤10例）组织中β-catenin核阳性的表达，同时检测韧带样型纤维瘤病中ER-α、ER-β和Ki-67的表达。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。