瘢痕疙瘩

In this study, the A allele of MCP_1 gene promoter _2518 may be associated with the formation and development of multiple keloids.

MCP_1基因_2518位A等位基因的存在可能与多发性瘢痕疙瘩的形成和发展有一定的相关性。

The results indicate that Smad2 plays an important role in TGF-beta-induced fibrosis in keloids.

结果显示smad2起着重要作用，在涉及TGF-致纤维化瘢痕疙瘩。

OBJECTIVE: To study the clinical genetics characteristics for Han familial keloids.

目的：分析汉族瘢痕疙瘩家系的临床遗传学特征。

MATERIALS: Keloids were derived from 5 cases.

材料：瘢痕疙瘩患者的手术标本5份，患者均知情同意。

Keloids may not develop for many months after injury, and can worsen during pregnancy.

瘢痕疙瘩在受伤后不可能发展数月，会在怀孕期间加重。

Objective: Investigate the expression of Discoidin domain receptors in keloids.

目的：研究圆盘状受体在瘢痕疙瘩形成和增殖中的作用。

Keloids may not develop for many months after injury, and can worsen during pregnancy.

瘢痕疙瘩不得制定伤后数月，并可以在怀孕期间恶化。

METHODS: Keloid tissues with prominences and redness were harvested. Subsequent to primary cultures, dermal fibroblasts at passages 3 to 4 were used in this study.

取瘢痕疙瘩边缘突起发红的部分，按组织块法培养原代成纤维细胞，取第三四代的细胞用于实验。

Western Blot showed that a Mr 62×103 ALK 1 protein could be expressed after transfecting pcDNA3.1/ALK 1 into HEK293 cells. CONCLUSION: Human full length ALK 1 cDNA is successfully cloned and can be expressed in transfected HEK293 cells, which provides a solid basis for exploring the effects of ALK 1 mediated TGFβ signal pathway in wound healing and the development of keloid. ALK 1; cloning, molecular; gene expression

为了深入研究ALK 1介导的TGFβ信号转导通路在创面愈合过程所发挥的作用，并探索阻断该通路是否可抑制瘢痕疙瘩的发生，发展，我们克隆了人ALK 1基因并制备了真核表达载体，为进一步的工作奠定了基础。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。