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瘢痕疙瘩

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Objective To explore the effect of connective tissue growth factor on the pathogenesis of hypertrophic scar and keloid tissue.

目的探讨结缔组织生长因子在增生性瘢痕和瘢痕疙瘩发病机制中的作用。

Objective To study the relationship between intra cellular actin and scar contracture.

目的 探讨增生性瘢痕、瘢痕疙瘩成纤维细胞中肌动蛋白与瘢痕挛缩的关系。

Objective To evaluate the clinical effect for treatment of keloid with triple therapy of Cica-Care and radiotherapy after operation.

目的:评价手术、放疗结合瘢痕敌外贴的"三联疗法"治疗瘢痕疙瘩的临床疗效。

Objective To evaluate the effect mechanism of Wubeizi Ointment on keloid.

目的 探讨五倍子瘢痕膏治疗瘢痕疙瘩的作用机制。

Key words: malxilloficd region; keloids; prevent scars from overgrow

颌面部;瘢痕疙瘩;预防瘢痕过度生长

The expression of VEGFmRNA was valued by in situ hybridation method and the expression of Fit-1 and MV count was investigated by using immunohistochemical method.

应用原位分子杂交方法研究VEGFmRNA的表达,应用免疫组化方法研究Flt-1表达及MV的计数。结果:增生性瘢痕和瘢痕疙瘩组织中MV数目多於正常皮肤和扁平瘢痕组织中的MV数目。

Background: Pathological scars may be divided into two kinds: hypertrophic scars and keloids.

背景:病理性瘢痕在临床上可分为增生性瘢痕和瘢痕疙瘩两种类型。

Objective:To investigate the expression of cyclinD1,P16 and cyclinA1 in the fibroblasts of keloids and hypertrophic scars,and explore the relationship between the genesis of two different kinds of scars.

目的:观察瘢痕疙瘩和增生性瘢痕中成纤维细胞的cyclinD1?p16和cyclinA1的表达,探讨其表达的差异与两种不同类型瘢痕的形成之间的关联性?

Methods The principle of activated-PKC to transfer phosphorus (32P) into substrate was used to calculate activity of PKC by detecting radioactivity of substrate with scintillation counter. Six cases of HS and K were studied.

利用PKC活化后催化底物多肽磷酸化,然后计数底物中掺入32P的放射活性的原理,测定增生性瘢痕、瘢痕疙瘩、成熟瘢痕和正常皮肤组织中PKC活性。

Methods The principle of activated- PTK to transfer phosphorus (32p) into substrate was used to calculate activity of PTK by detecting radioa ctivity of substrate with scintillation counter. Six cases of HS and K were measured.

方法利用活化的PTK催化底物多肽磷酸化,再计数底物中掺入32P的放射活性的原理,测定增生性瘢痕、瘢痕疙瘩、成熟瘢痕和正常皮肤组织中PTK活性。

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