瘢痕形成

Results There was no apparent gender difference among 14 patients. 9 patients were younger than 30 years old. Pathological examination showed that bronchial infiltration of eosinophils in 14 patient (100%), thickened basement membrane of the bronchial mucosa in 12 patients (85.7%), proliferation of smooth muscle cells in 11 patients (78.6%), proliferative mucous gland in 9 patients (64.3%), mucous plug in bronchiole in 8 patients (57.1%), and cicatvization of left ventricle in 10 patients (71.4%).

结果哮喘猝死患者无性别差异，年龄30岁以下者9例(64.3%)；病理改变的特点为支气管管壁嗜酸细胞浸润14例(100%)，粘膜基底膜增厚12例(85.7%)，支气管平滑肌细胞增生11例(78.6%)，粘液腺增生、肥大9例(64.3%)，细支气管内粘液栓形成8例(57.1%)；左心室壁瘢痕形成10例(71.4%)，病变主要位于左心室侧壁和心尖部。

The recombinant antisense GFAP retrovirus can effectively inhibit the growth of glial cicatrix formation in vivo. This result provides a new way for delaying or suppressing glial cicatrix formation by the technique of gene engineering.

重组反义GFAP逆转录病毒能在一定程度上减少胶质瘢痕形成，为利用基因工程技术延缓或抑制胶质瘢痕形成提供了新的实验依据。

Objective To examine the expression of p44/42 mitogen -activated protein kinase (p44/42MAPK) and Phospho-p44/42MAPK in cicatrix and to aim at exploring the role of activated p44/ 42 MAPK pathway in development of cicatrix.

目的 研究丝裂素原激活的蛋白激酶(p4 4 / 4 2MAPK)在异常瘢痕(瘢痕疙瘩和增生性瘢痕)中的表达和激活情况，探讨该信号通路在瘢痕形成中的作用。

RESULTS AND CONCLUSION: The effect of different cells in epithelial tissue is known to all.

结果与结论：①上皮组织中各类上皮细胞的生理作用是明确已知的，其中研究最多的是角质形成细胞和成纤维细胞，并且与瘢痕形成密切相关。

Objective: To investigate the efficacy and feasibility of mitomycin C drug delivery system as a new glaucoma anti-scarring agent by observing its effects on a rabbit model of glaucoma filtration surgery and side effects on eyelid,conjunctiva,cornea,and anterior champer of rabbit eye.

目的：研究丝裂霉素C缓释系统(mitomycin C drug delivery system，MMC DDS)对兔眼滤过性手术后抗瘢痕形成的疗效及对兔眼局部组织的毒副作用，探讨其作为青光眼滤过性手术后抗瘢痕形成的辅助用药的可行性和有效性。

Gruanulation tissue hyperplasia in myocardial infarction was found in group Ⅲ,but no obvious cicatrices.In group Ⅴ,some cicatrices were observed.

光学显微镜观察结果表明，AMI组心肌梗塞处肉芽组织增生，未见明显瘢痕形成，磁场治疗组心肌梗塞处可见部分瘢痕形成。

BACKGROUND: Fibration and scar formation are major factors for surgical failure following glaucoma filtration. Although there are so many drugs and methods to inhibit scar formation, they are not ideal.

背景：青光眼滤过后，滤过道的纤维化与瘢痕组织形成，是手术失败的主要原因，虽然抑制青光眼滤过术后瘢痕形成的药物和给药方法很多，但多不理想。

Our studies indicate that the increased contents of glucose and accumulation of active metabolic intermediates due to metaboic disorder contribute to the cutaneous environmental alterations associated with diabetes mellitus.Thus,the cutaneous environmental alteration is one of the initial events for impaired healing.The succession of progressive injury in deep partial thickness burn wounds is carried out depending on the physiological outcome of parabiotic tissues.The loss of dernal template due to the damage to the integrity and the continuity of dermal tissue may be one of the leading reasons of hyperplastic scar formation.

通过对糖尿病合并创面难愈、烧伤创面的进行性损害以及增生性瘢痕形成的机制研究，我们发现：糖尿病代谢紊乱所致皮肤组织中糖含量增高和代谢产物蓄积引起的皮肤微环境改变，是导致糖尿病创面难愈的始动因素之一；烧伤后的组织进行性损害的发生发展取决于&间生态&组织的病理转归；真皮组织缺损导致的模板作用缺失可能是引起增生性瘢痕形成的始动环节。

Methods Constructed the model of fetal scarless wound healing and investigated the expression of collagen in fetal and adult rat wounds by immunohistochemistry and in situ hybridization.

染色，Ⅰ、Ⅲ型胶原免疫组化，Ⅰ、Ⅲ型胶原原位杂交。结果胎鼠伤口愈合快，组织结构再生完全，没有瘢痕形成，胶原呈网状正常排列，Ⅰ、Ⅲ型胶原蛋白及表达均增多，同时伴细胞数增多，Ⅲ型胶原首先形成网状排列；成年伤口胶原纤维沉积慢，平行排列的胶原逐渐呈束状填塞伤口以致瘢痕形成，伤口内Ⅰ、Ⅲ型前胶原mRNA表达均增多，细胞数目增多不明显。

Objective: To probe into the role of periostin in the formation of scars and investigate its reaction to hydrocortisone.

目的：通过检测periostin在人过度增生性瘢痕成纤维细胞中的表达及其对氢化可的松作用的反应，探讨periostin在瘢痕形成中的作用。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。