痣

It is an unusual clinical presentation of speckled lentiginous nevus which must be differentiated from benign pigmented lesions due to a potential for malignant changes.

此例为斑点状小痣样母斑临床上较特殊的表现，且因其有恶性变化的可能，故须与其他良性色素病灶作鑑别。

Speckled lentiginous nevus is characterized by a tan or light brown background patch on which more darkly pigmented macules or papules are randomly distributed .

斑点状小痣样母斑，其特徵是许多颜色较深的斑点或丘疹散布在一块褐色或淡棕色的斑块上。

Importantly, depletion of ARMS facilitated UVB-induced apoptosis in melanoma cells through inactivation of MEK/ERK pathway, which is not constitutively activated in most cases of acral lentiginous melanoma, the melanoma subtype found mostly in Asians.

更重要的是，减少ARMS在黑色素细胞癌细胞的表现，会促进紫外线B光诱发之细胞凋亡，其作用机转是透过MEK/ERK传递路径之抑制，此路径在多数亚洲人常见的肢端小痣型黑色素细胞癌并无自身活化之现象。

Primary melanocytoma (benign; also known as cellular blue nevus or melanotic schwannoma) or diffuse malanosis are very rare conditions of the leptomeninges.

脑膜或脊膜部位的原发黑色素细胞瘤（良性，又称细胞性蓝痣或黑色素性施万氏瘤）或弥漫性黑变病在非常罕见。

Methods PCR- SSCP and DNA sequencing were used to analyze the PTCH gene mutations in 12 OKCs, including 10 sporadic and 2 nevoid basal cell carcinoma syndrome associated OKC.

方法采用PCR—SSCP筛查与DNA直接测序的方法对12例OKC进行PTCH基因突变的检测，其中2例为痣样基底细胞癌综合征相关OKC，10例为散发OKC。

Recently, the gene responsible for nevoid basal cell carcinoma syndrome, an autosomal dominant disorder characterized by multiple malformations and susceptibility to a variety of tumors and, particularly, to BCC, has recently been identified as PTCH.

痣样基底细胞癌症候群是一种体染色体显性遗传疾病，其主要表现有基底细胞癌、成齿的角质囊肿和其他多种骨骼发育异常，这个疾病被认为和PTCH基因突变有关。

Multiple odontogenic keratocysts of jaw is one of the most important clinical manifestation of BCNS.

多发性颌骨角化囊肿是基底细胞痣综合征的重要临床表现之一，及时正确的治疗能使患者获得良好的生存质量。

Results It was found that the most frequent sites of BCC were the nose and periocular area,the age of highest incidence of BCC was ranged from 40 to 49, and solid BCCs were most common compared with other types. 28.57% of the cases were misdiagnosed clinically as pigmented nevus, seborrheic keratosis, malignant melanoma, et al.

结果：BCC最好发的部位是鼻部和眼周，发病年龄高峰40～49岁，实体型BCC最常见，28.57%的病例临床上被误诊为色素痣、脂溢性角化、恶性黑素瘤等。

Of the 30 cases not receiving liver biopsy, 25 cases were diagnosed by peritoneoscopy; 5 cases could not be diagnosed by peritoneoscopy but the diag...

主要体征有肝大(98.2％)、消瘦(30％)、脾大(19.7％)、黄疸(16.7％)、腹水(4％)、蜘蛛痣(4％)等。82％病例自首发症至就诊时的病程为6个月以内，仅18％在6个月以上。

Spring and summer are predilected seasons of pediatric vitiligo. Halo nevi were found in 73 （11.77%） children,and most in those with scattered vitiligo.

发病季节和疾病进展均以春夏季为多。73例患儿伴有晕痣，占11.77%，以散发型者居多。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。